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Department of Otolaryngology – Head & Neck Surgery, Chinese PLA General Hospital
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Biochip National Engineering Research Center
Aomaier Genetic Technology Limited Company
Contact Us
For enquiries, please contact the Conference Secretariat:
Conference Secretariat of ISDGM2009
Genetic Testing Center for Deafness,
Inst. of Otolaryngology,
Tel: (86) 10-6815 7998 (Mandarin and English)
Fax: (86) 10-6815 7998
Email:
daisy9716@yahoo.com.cn
(Dr. Bing Han)
wjcmu@163.com
(Dr. Guo-Jian Wang)
| Simon I. Angeli, M.D. |
|
Professor of Clinical Otolaryngology, University of Miami School of Medicine. Dr. Simon graduated from Universidad Central de Venezuela in 1987, then he studied and worked in the department of Otolaryngology-Head and Neck Surgery at the University of Iowa Hospitals and Clinics and in the department of Neurotologic Skull Base Surgery at House Ear Clinic.
His research interests:1)Translational research in hereditary deafness, phenotype/genotype correlations; molecular screening for nonsyndromic deafness and presbycusis. 2)Role of oxidative stress in sudden sensorineural hearing loss, analysis of polymorphisms of enzymes involved in oxidative stress and clinical response to treatment with antioxidants (funded clinical trial). 3)Middle ear surgery for otitis media and otosclerosis, use of hyaluronic acid gel for middle ear wound healing (funded research) 4)Cochlear implantation outcomes, surgery, avoidance of trauma. 5)Vestibular disorders, clinical outcomes 6)Acoustic neuroma surgery and outcome.
CURRICULUM VITAE
NAME： SIMON I. ANGELI
Current position: Professor of Clinical Otolaryngology, University of Miami School of Medicine, Miami, Florida, U.S.A.
Education:
Fellowship: House Ear Clinic, Los Angeles, California
July 1994 – June 1995
Neurotologic Skull Base Surgery
Residency: University of Iowa Hospitals and Clinics, Iowa City, Iowa
July 1990 – June 1994
Otolaryngology-Head and Neck Surgery
Research Fellowship: University of Iowa Hospitals and Clinics, Iowa City, Iowa
July 1989 – June 1990
Otolaryngology-Head and Neck Surgery
Internship: University of Iowa Hospitals and Clinics, Iowa City, Iowa
July 1988 – June 1989
General Surgery
Medical School: Universidad Central de Venezuela, Caracas, Venezuela
September 1980 – December 1986
Date of graduation: March 7th, 1987
Research Interests:
Translational research in hereditary deafness, phenotype/genotype correlations; molecular screening for nonsyndromic deafness and presbycusis.
Role of oxidative stress in sudden sensorineural hearing loss, analysis of polymorphisms of enzymes involved in oxidative stress and clinical response to treatment with antioxidants (funded clinical trial).
Middle ear surgery for otitis media and otosclerosis, use of hyaluronic acid gel for middle ear wound healing (funded research)
Cochlear implantation outcomes, surgery, avoidance of trauma.
Vestibular disorders, clinical outcomes
Acoustic neuroma surgery and outcome.
Selected Publications:
1. Bared A, Angeli SI. Malleus handle: determinant of success in ossiculoplasty . Accepted for publication, American Journal of Otolaryngology Head and Neck Medicine and Surgery 2009.
2. Amit Kochhar, Simon I Angeli, Sandeep Dave, Xue Z. Liu. Imaging correlation of children with DFNB1 versus non-DFNB1 hearing loss. Otolaryngology Head and Neck Surgery 2009.
3. Angeli SI. Phenotype/genotype correlations in a DFNB1 cohort with ethnic heterogeneity. Laryngoscope, May 2008.
4. Xue Z. Liu, Simon I. Angeli, Kaukab Rajput, Denise Yan, Annelle V. Hodges, Adrien Eshraghi, Fred F. Telischi, Thomas J. Balkany. Cochlear implantation in individuals with Usher type 1 syndrome. International Journal of Pediatric Otorhinolaryngology (2008) 72, 841-847.
5. Christine Dinh, Kimberly Hoang, Scott Haake, Shibing Chen, Simon I. Angeli, Eva Nong, Adrien Eshraghi, Thomas J. Balakny, and Thomas R. Van De Water. Biopolymer-Release Dexamethasone Prevents Tumor Necrosis Facor a Induced Loss of Auditory Hair Cells In Vitro: Implications Toward the Development of a Drug-Eluting Cochlear Implant Electrode Array. Otology & Neurology 2008; 29:1012-1019.
6. Connell S, Angeli SI, Suarez H, et al. Performance after cochlear implantation in DFNB1 patients. Otolaryngol Head Neck Surg; 137:596-602 2007
7. Angeli SI, van de Water T, Connell S, Ozdek, et al. Injectable form of cross-linked hyaluronan is effective for middle ear wound healing. Annals Otol Rhino Laryngol; 116:667-673 2007
8. Utreta R, Angeli SI. Detection of the 35delG/GJB2 and del (GJB6-D13S1830) mutations in Venezuelan patients with autosomal recessive non-syndromic hearing loss. Genet Testing May 10, 2007
9. Yan D, Ouyang XM, Angeli SI, et al. Paternal uniparental disomy of chromosome 13 causing homozygous 35delG mutation of the GJB2 gene and hearing loss. AM J Med Genet Part A 143A:385-386, 2007
10. Suarez H, Angeli SI, Suarez A. Balance Sensory Organization in Children with Profound Hearing Loss and Cochlear Implants. Int J Pediatr Otorhinolaryngol 71: 629-637 2007
11. Angeli SI, Kulak J, Guzman J. Lateral tympanoplasty for total and near-total perforations: prognostic factors. Laryngoscope 116:1594-1599, 2006.
12. Ulubil AS, Furze A, Angeli SI. Cochlear implantation in a patient with profound hearing loss with the A1555G mitochondrial DNA mutation and no history of aminoglycoside exposure. J Laryngol Otol 120:230-2 2006
13. Simon I. Angeli MD. Hyaluronate gel stapedotomy. Otolaryngology-Head and Neck Surgery, Volumen 134, No. 3, pp 225-231, 2006
14. Simon I. Angeli, MD, Denise Yan, PhD, Fred Telischi, MD, Thomas J. Balkany, MD, Xiao M. Ouyang, MD, Li L. Du, MSC, Adrian Eshraghi, MD, Leslie Goodwin, MSN, Xue Z. Liu, MD, PhD. Etiologic diagnosis of sensorineural hearing loss in adults. Otolaryngology-Head and Neck Surgery, Volumen 132, No. 6, pp 888-893, 2005.
15. Simon I. Angeli, MD, Xue Z. Liu, MD PhD, Denise Yan PhD, Thomas Balkany, MD, Fred Telischi, MD. Coenzyme Q-10 treatment of patients with a 7445A>G mitochondrial DNA mutation stopped the progression of their hearing loss. Acta Oto-Laryngologica;125:1-3 2005
16. Liu XZ, Pandya A, Angeli SI, Telischi FF, Arnos KS, Nance WE, Balkany T. Audiological Features of GJB2 (Connexin 26) Deafness. Ear & Hearing; 26:361-369 2005
17. Ouyang XM, Yan D, Du LL, Hetjmancik JF, Jacobson SE, Nance WE, Li AR, Angeli SI, Kaiser M, Newton V, Brown SDM, Balkany T, Liu XZ. Characterization of Usher syndrome type I gene mutations in an Usher syndrome patient population. Hum Genet;116:292-299 2005
18. Ouyang XM, Hejtmancik JF, Jacobson SG, Li AR, Du LL, Angeli SI, Kaiser M, Balkany T, Liu XZ. Mutational spectrum in Usher syndrome type II. Clin Genet. 2004 Apr;65(4):288-93. Erratum in: Clin Genet;65(5):433 May 2004.
19. S Angeli, O Gomez and R Hawley. Systematic approach to BPPV in the elderly. Otolaryngology-Head and Neck Surgery 128:719-25 2003
20. S Angeli. The value of quantitative vestibular testing in infants and young children with sensorineural hearing loss. Archives of Otolaryngology-Head and Neck Surgery; 129: 478-482 2003
21. Angeli SI and Balkany TJ. Post-cochlear implant meningitis. Operative Techniques in Otolaryngology-Head and Neck Surgery;14(4):293-296 2003
22. Liu XZ, Xia XJ, Ouyang XM, Ke XM, Wang HL, Angeli S, Du LL, Telischi F, Liu YH, Balkany T, Nance WE, Xu LR. The prevalence of the conexin 26 (GJB2) mutations in the Chinese population. Human Genetics;11:394-7 2002
23. Angeli SI, A De La Cruz, and Hitselberger T. The transcochlear approach revisited. Otology and Neurotology; 22:690-695 2001
24. S Angeli, R Utrera, S Dib, E Chiossone, C Naranjo. GJB2 mutations in childhood deafness. Acta Otolaryngol (Stockh) 120: 133-136 2000
S Angeli, C. Naranjo, R.A. Freidman, A. Naranjo, O. Henriquez, N. Fischel-Ghodsian and E. Chiossone. An analysis of a large postlingually deaf family with hereditary non-syndromic profound Hearing loss. Acta Otolaryngol (Stockh); 119: 158-162 1999 |
