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Department of Otolaryngology – Head & Neck Surgery, Chinese PLA General Hospital
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Contact Us
For enquiries, please contact the Conference Secretariat:
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Inst. of Otolaryngology,
Tel: (86) 10-6815 7998 (Mandarin and English)
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| Cynthia Casson Morton |
|
Cynthia Casson Morton received her Bachelor’s of Science degree from the College of William and Mary in Virginia and her Ph.D. in Human Genetics from the Medical College of Virginia in Richmond. She is the William Lambert Richardson Professor of Obstetrics, Gynecology and Reproductive Biology and Professor of Pathology at Harvard Medical School, Associate Director of the Harvard-Partners Center for Genetics and Genomics, and Co-Director of the Biomedical Research Institute and Director of Cytogenetics at Brigham and Women’s Hospital. Dr. Morton is certified by the American Board of Medical Genetics in Ph.D. Medical Genetics, Clinical Cytogenetics and Clinical Molecular Genetics. Her research interests are in molecular cytogenetics, hereditary deafness, genetics of uterine leiomyomata and human developmental disorders.
As Director of Cytogenetics, Dr. Morton oversees one of the largest full-service academic cytogenetics laboratories in the country. This laboratory has been at the forefront in implementing molecular methods in diagnostic testing for chromosome studies that cross the lifespan. These tests include preimplantation and prenatal diagnostics, perinatal and childhood studies in the evaluation of congenital and developmental disorders, infertility and pregnancy loss studies, and cytogenetics of leukemias, lymphomas and solid tumors. Her laboratory has been a major site for training laboratory geneticists in clinical cytogenetics.
Dr. Morton is a past member of the Board of Directors of the American Board of Medical Genetics where she served as Secretary, Treasurer and Chair of the Accreditation Committee. She was the Chair of the Molecular Genetic Pathology Policy and Exam Committees of the American Board of Medical Genetics and the American Board of Pathology. She served as a member and Chair of the Board of Scientific Counselors of the National Institute of Deafness and Other Communication Disorders. Currently she is a member of the Counsel of Scientific Trustees of the Deafness Research Foundation and serves as Chair of the Board of Regents of the National Library of Medicine at the National Institutes of Health. Dr. Morton is currently a member of the Board of Directors of the American Society of Human Genetics and is Editor of The American Journal of Human Genetics.
CURRICULUM VITAE
NAME: Cynthia Casson Morton
ADDRESS: New Research Building, Room 160D
Harvard Medical School
77 Avenue Louis Pasteur
Boston, MA 02115
Tel: (617) 525-4535
Fax: (617) 525-4533
This e-mail address is being protected from spambots. You need JavaScript enabled to view it
PLACE OF BIRTH: Atlanta, Georgia
EDUCATION:
1973-77 B.S. in Biology, The College of William and Mary in Virginia
Williamsburg, VA
1977-82 Ph.D. in Human Genetics, Medical College of Virginia
Richmond, VA
Laboratory of Judith A. Brown, Ph.D.
POSTDOCTORAL TRAINING:
1982-83 Research Fellow in Pediatrics, Division of Clinical Genetics
Children's Hospital, Harvard Medical School, Boston, MA
Laboratory of David M. Kurnit, M.D., Ph.D.
1983-87 Research Fellow in Genetics, Department of Genetics
Harvard Medical School, Boston, MA
Laboratory of Philip Leder, M.D.
LICENSURE AND CERTIFICATION:
American Board of Medical Genetics
1984 Clinical Cytogenetics (Certificate #1779)
1984 Medical Genetics (Certificate #1779)
1993 Clinical Molecular Genetics (Certificate #93211)
ACADEMIC APPOINTMENTS:
1987-91 Assistant Professor of Pathology
Harvard Medical School, Boston, MA
1992-96 Associate Professor of Pathology
Harvard Medical School, Boston, MA
1996- William Lambert Richardson Professor of Obstetrics, Gynecology and
Reproductive Biology
Professor of Pathology
Harvard Medical School, Boston, MA
2003- Member of the Affiliated Faculty of the Harvard-MIT Division of Health Sciences and
Technology
HOSPITAL APPOINTMENTS:
1987- Director of Cytogenetics, Brigham and Women's Hospital, Boston, MA
1992-95 Consultant, New England Medical Center Hospitals, Boston, MA
2001 Associate Director, Harvard-Partners Center for Genetics and Genomics
2005-08 Co-Director, Brigham and Women’s Hospital Biomedical Research Institute
2008 10 Director, Brigham and Women’s Hospital Biomedical Research Institute
OTHER PROFESSIONAL POSITIONS AND MAJOR VISITING APPOINTMENTS:
1990-93 Scientific Advisory Board, Oncor, Inc.
1990-92 Consultant, Collaborative Research, Inc.
1992 Consultant, Baystate Medical Center
1993 Consultant, Dianon, Inc.
2006 Associate Member, Broad Institute of MIT and Harvard
AWARDS AND HONORS:
1974 Phi Sigma (Biological Honorary), The College of William and Mary
1976 Mortar Board (National Scholastic Honorary), The College of William and Mary
1978 A.D. Williams Summer Research Fellowship, Medical College of Virginia
1978‑79 Training Assistantship, Medical College of Virginia
1980 Alpha Sigma Chi Society for Leadership in Science, Medical College of Virginia
1979‑82 NIH Institutional Predoctoral Traineeship, Medical College of Virginia
1982 Roscoe D. Hughes Award in Human Genetics, Medical College of Virginia
1982‑83 Howard B. Sprague Fellow of the American Heart Association, Children's Hospital, Harvard Medical School
1983‑84 Damon Runyon-Walter Winchell Cancer Fund Fellowship, Department of Genetics, Harvard Medical School
1984‑87 NIH Individual Postdoctoral Fellowship, Department of Genetics, Harvard Medical School
1992 Outstanding Alumnus of the Year for Basic Health Sciences Division, Medical College of Virginia, Richmond
1997 Warner-Lambert/Parke-Davis Award, American Society of Investigative Pathology
1999 Fanger Lecture, Department of Pathology and Laboratory Medicine, Brown University School of Medicine, Providence, RI
1999 Robert C. Knapp, M.D. Lecturer in Gynecology, Brigham and Women's Hospital, Boston, MA
2001 VCU Life Sciences Advisory Board, Virginia Commonwealth University, Richmond
2001 Council of Scientific Trustees, Deafness Research Foundation
2002- Advisory Committee, University of Nebraska Neurosensory CoBRE
2003 Mary Horrigan Conners Award, Brigham and Women’s Hospital
2004 MacArthur Research Service Award, Brigham and Women’s Hospital Research Council
2008 Advisory Board, The Raphael Recanati Genetic Institute, Rabin Medical Center, Petach Tikva, Israel
MAJOR COMMITTEE ASSIGNMENTS:
National:
1987 Evaluation of NIGMS Human Genetic Mutant Cell Repository
1988‑92 NIH Advisory Committee, Human Genetic Mutant Cell Repository (Coriell Institute for Medical Research, Camden, NJ)
1989 NIH-NIDR Special Review Group for Craniofacial Anomalies Research Centers
1990 NIH-NCI Special Review Committee for Germ Cell Program Project at Memorial Sloan-Kettering Cancer Center
1991 NIH-NCI Workshop, "Investigational Strategies for Detection and Intervention in Early Lung Cancer"
1991 NIH-NCI Special Review Committee for Soft Tissue Sarcoma Program Project at Memorial Sloan-Kettering Cancer Center
1992 NIH-NCI Special Review Committee for Soft Tissue Sarcoma Program Project at Memorial Sloan-Kettering Cancer Center
1992 NIH-NIDCD Special Review Committee for Molecular Genetics of the Auditory System Program Project at Boys Town National Research Center
1992 Special Reviewer for NIH Mammalian Genetics Study Section
1993 Special Reviewer for NIH Hearing Research Study Section
1993 NIH-NIGMS Contract Review for Human Genetic Mutant Cell Repository
1993- Community Editor for Chromosome 15, HUGO Human Gene Mapping Committee; Senior Editor 1997
1993-97 Regular Member, Mammalian Genetics Study Section
1994-95 Special Reviewer, National Multi-Purpose Research and Training Centers, NIH-NIDCD
1995-96 Integrated Planning and Policy Committee, NIH-NIDCD
1996-01 Board of Scientific Counselors, NIH-NIDCD; Chair 1998-01
1996 Special Reviewer, NIH-NIMH
1997 Special Reviewer, DOE EpSCOR grants
1997, 99 Reviewer, Department of the Army Breast Cancer Research Awards
1997 Co-organizer, 4th International Workshop on Human Chromosome 15, Baltimore, MD
1997 Co-organizer, Workshop at the 47th annual meeting of the American Society of Human Genetics, "How Hearing Happens: Molecular Genetics of Hearing Impairment in Man and Mouse", Baltimore, MD
1998 Special Reviewer, Novel Technologies Grants, NIH-NCI/NIDCD
1998 NIH-NIDCD Blue Ribbon Review Panel
1998 Reviewer, Department of the Army Ovarian Cancer Research Awards
1998-04 Organizing Committee, 3rd-5th meeting, Molecular Biology of Hearing and Deafness, Bethesda, MD
1999 Special Reviewer, NIH-NIDCD
1999 Reviewer, The Jeffress Trust, NationsBank
1999 Reviewer, The Foundation Fighting Blindness
1999 Reviewer, Ohio Cancer Research Associates
1999 Special Reviewer, NIH-NIDCD
2000 Co-chair, NIH-NCI Workshop on Cancer Chromosome Aberration Database
2000 NIH-NCI Advisory Group on Cancer Chromosome Aberration Database
2000 Special Reviewer for NIH IFCN (6) Study Section
2000 Special Reviewer, Innovative Technologies for the Molecular Analysis of Cancer, NIH-NCI
2000 NIH-NHGRI Reviewer for Cancer Genetics and Inherited Diseases Research Branches
2001- Executive Committee, Reproductive Scientist Development Program
2001 Special Reviewer for NIH IFCN (5) Study Section
2001 American College of Medical Genetic Expert Panel, Guidelines for the Etiologic Diagnosis of Congenital Hearing Loss
2001 Reviewer for the Cancer Research Campaign, Section of Cancer Genetics, Institute of Cancer Research, London, England
2002 Roadmap Focus Group, NIH
2002 Co-organizer, Symposium at the 52nd annual meeting of the American Society of Human Genetics, “Hereditary Hearing Loss: Lessons Learned and Advances Ahead”, Baltimore, MD
2002 Genetics Study Section Boundaries Team, NIH
2003 Airlie II, Beyond the Beginning: The Future of Genomics II, NHGRI
2003 Co-organizer, 34th annual March of Dimes Clinical Genetics Conference on Deafness, San Diego, CA
2003 Reviewer, The Foundation Fighting Blindness
2004 Special Reviewer, NIH-NIDCD
2004 Reviewer, The Foundation Fighting Blindness
2004 Special Reviewer, NIH-NIDCD
2004 Special Reviewer, NIH-NIGMS Site Visit of T32 at Yale University
2004-05 Regular Member, IFCN6 Study Section, NIH
2004 External Advisory Committee, Genetics/Genomics Affinity Group, The Children's Hospital of Philadelphia
2004 Site Visit of NCI Cancer Genetics Branch
2004 Advisory Board on Graduate Studies, The College of William and Mary in Virginia; Vice President, 2008
2005 Program Committee, American Association for Cancer Research
2006-09 Board of Regents, National Library of Medicine, NIH
2006 Invited Participant, NIH Workshop on Criteria for Replication of Genotype-Phenotype Associations
2007-09 Chair, Board of Regents, National Library of Medicine, NIH
2007 Reviewer, AIRC - Italian Association for Cancer Research
2007 Invited Participant, NESCent Catalysis Meeting, Evolution in Contemporary Human Populations: Medical, Genetic and Behavioral Implications, Duke University, Durham, NC
2007 Reviewer, The Jeffress Trust, Bank of America
2008 Reviewer, The Jeffress Trust, Bank of America
2008 Reviewer, AIRC - Italian Association for Cancer Research
2008 Special Reviewer, NIH-NIGMS T32 applications
Harvard Medical School:
1997- Standing Committee on Conflicts of Interest and Commitment
1997-02 Reviewer for 50th Anniversary Program for Scholars in Medicine
1999-02 Subcommittee of Professors
1999- Standing Committee on Faculty Fellowships
2001-07 Executive Committee, Department of Pathology, Harvard Medical School
2003-04, 06 Admissions Committee, Biological and Biomendical Sciences Program, Division of Medical Sciences
Partners HealthCare System:
1997- Task Force on Genetics: Pilot Projects
1997-05- Committee on Senior Appointments
2000- Genetics Research Advisory Panel
2003- Partners Professional and Institutional Conduct Committee
2004- Steering Committee for Harvard-Partners Center for Genetics and Genomics
2005 Partners Research Council
2005- Selection Committee, William K. Bowes, Jr. Award in Medical Genetics
Brigham and Women's Hospital:
1997- Genetics Initiative Committee (Co-chair)
1997- Research Career Development Committee
2000-02 Committee on Interdisciplinary Programs
2003 Research Planning Committee
MEMBERSHIPS, OFFICES, AND COMMITTEE ASSIGNMENTS IN PROFESSIONAL SOCIETIES:
Memberships:
1978- American Society of Human Genetics
1979- American Association for the Advancement of Science
1981- Sigma Xi
1984- American Board of Medical Genetics
1988- American Society for Investigative Pathology
1992- Human Genome Organization (HUGO)
1992- American College of Medical Genetics
1995 Association for Research in Otolaryngology
Offices:
1996-01 Board of Directors, American Board of Medical Genetics
1997-99 Secretary, Board of Directors, American Board of Medical Genetics
2000 Accreditation Chair, American Board of Medical Genetics
2000 Vice Chair, Molecular Genetic Pathology Policy Committee, American Board of Medical Genetics/American Board of Pathology
2000-04 Chair, Molecular Genetic Pathology Exam Committee, American Board of Medical Genetics/American Board of Pathology
2000-01 Treasurer, Board of Directors, American Board of Medical Genetics
2001 Chair, Molecular Genetic Pathology Policy Committee, American Board of Medical Genetics/American Board of Pathology
2003-10 Board of Directors, American Society of Human Genetics
Committee Assignments:
1993-95 Program Committee, American Society of Human Genetics
1999-01 Awards Committee, American Society of Human Genetics
EDITORIAL BOARDS:
1995-99 American Journal of Medical Genetics
1996- 03 Genomics (Associate Editor)
1996- Journal of Experimental Zoology
1999- Genes, Chromosomes and Cancer
1999-01 American Journal of Human Genetics
2001 Human Genetics
2006-10 Editor, American Journal of Human Genetics
2007- International Journal of Clinical and Experimental Pathology
2008 The Application of Clinical Genetics
2008 Audiology and Neurotology
2008 International Journal of Women’s Health
2008 Cancer Management and Research
MAJOR RESEARCH INTERESTS:
Biology of uterine leiomyomata
Biology of hearing and deafness
Gene mapping
Clinical and molecular cytogenetics
RESEARCH FUNDING INFORMATION
Past:
1987-91 NIH/R01 PI Characterization of the myc Multigene Family
Current:
1990-13 NIH/R01 PI Cloning Genes Involved in Hearing
1992-06 NIH/R01 PI Molecular and Cytogenetic Studies of Uterine Leiomyomata
2001-14 NIH/P01 PI DGAP: Developmental Genome Anatomy Project
2003-08 NIH/R01 PI Finding Genes for Fibroids
1999-2012 NIH/T32 PI: Training Grant in Genetics
PRINCIPAL CLINICAL AND HOSPITAL SERVICE RESPONSIBILITIES:
1987- Director of Cytogenetics, Brigham and Women's Hospital
1996- Director of Cytogenetics, Partners HealthCare System
MAJOR ADMINISTRATIVE RESPONSIBILITIES:
1987- Director of Cytogenetics, Brigham and Women's Hospital
1999- Program Director, Women’s Reproductive Health Research Career Development Center, Brigham and Women’s Hospital
2002-04 Program Director, Harvard Medical School American Board of Medical Genetics Training Program
2003- Prinicipal Investigator, Genetics Training Grant at Harvard Medical School
2006-08 Co-Director, BWH Biomedical Research Institute
2008-10 Director, BWH Biomedical Research Institute
SELF REPORT OF TEACHING:
Local Contributions:
2009 Genetics 202, Principles of Genetic Analysis in Humans
2009 Lecturer, BWH Ob/Gyn Residents Series
2009 HMS Genetics Boot Camp
2007-08 HMS Human Genetics Course- Journal Club
2007 Block Course Instructor, Molecular Cytogenetics in Human Disease
2005 Breakout Session Leader, Harvard Medical School Leadership Development for Physicians and Scientists
2003-04 Lecturer, Harvard Medical School American Board of Medical Genetics Training Program
2000-01 Lecturer, Molecular Medicine Course for Harvard Medical School MD/PhD program
1998, 01 Lecturer, Clinical Pathology Lecture Series, Department of Pathology, Brigham and Women's Hospital
1994 Co-director of HST 703/PATH 205 "Molecular Biology of the Auditory System", Harvard Medical School
1991, 97, 98 Lecturer, Genetics, HST Program, Harvard Medical School
1990-06 Lecturer, Genetics, Development and Reproductive Biology, Harvard Medical School
1988-89, 91-93 Tutor, Genetics, Embryology and Reproduction, Harvard Medical School
1984-85, 87 Section Instructor, Genetics, Harvard Medical School
1984 Lecturer, Human Genetics, Harvard University Extension
Regional, National or International Contributions:
1983, 98 Lecturer, Short Course in Medical and Experimental Mammalian Genetics, The Jackson Laboratory, Bar Harbor, ME
1981 Lecturer, Human Genetics in Clinical Practice, J. Sargeant Reynolds Community College, Richmond, VA
1977 Laboratory Instructor, Inorganic Chemistry, Chesapeake Community College, Wye Mills, MD
INVITED ADDRESSES
1997
"Immunogenetics of the Human Blood Groups: The ABO and Rh Systems"
Easton Memorial Hospital, Easton, MD, Nov 1977
1978
"Introduction to Genetic Diseases"
Richmond Memorial Hospital, Richmond, VA, Oct 1978; Mar 1979; Oct 1979; Mar 1980; Oct 1980; Mar 1981
"The Human Blood Groups: The ABO and Rh Systems"
Saturday Morning Explorer Program, Medical College of Virginia, Richmond, Oct 1978
1979
"What is Tay-Sachs Disease?"
Jewish Community Center, Richmond, VA, Apr 1979; May 1979
"Spondylothoracic Dysplasia with Anal and Urogenital Anomalies: A New Syndrome?"
Genetics and Connective Tissue Rounds, Medical College of Virginia, Richmond, Dec 1979
1980
"What is Genetics?"
Jewish Day School, Richmond, Virginia, Feb 1980
"Major Chromosome Anomalies in Man"
Saturday Morning Explorer Program, Medical College of Virginia, Richmond, Nov 1980
"Genetic Engineering: Prospects and Perils"
Patrick Henry High School, Ashland, VA, Nov 1980
"Trisomy 6p: Case Presentation"
Genetics and Obstetrics Rounds, Medical College of Virginia, Richmond, Dec 1980
1982
"Studies of the Human Nucleolus Organizer Region"
Department of Human Genetics, University of Pennsylvania, Philadelphia, Mar 1982
"Gene Mapping by Chromosomal In Situ Hybridization"
Division of Clinical Genetics, Children's Hospital, Boston, MA, Sept 1982
"Usefulness of Chromosomal In Situ Hybridization in Mapping the Major Histocompability Complex"
Department of Biochemistry and Molecular Biology, Harvard University, Boston, MA, Oct 1982
"Usefulness of Molecular Genetic Technologies in Understanding Human Cytogenetic Disorders"
Department of Biology, University of Massachusetts, Boston, Nov 1982
1983
"Mapping Oncogenes"
Hematology and Oncology Grand Rounds, Children's Hospital, Boston, MA, Feb 1983
"Translocation of the c-myc Oncogene in Human Burkitt Lymphoma and Murine Plasmacytoma Cells"
Biology 99f Tutorial Program, Harvard University, Boston, MA, Feb 1983
1984
"Legal Issues Pertaining to Human Genetics"
Senior Seminar, Brandeis University, Waltham, MA, Mar 1984 and Mar 1985
"New Developments in Cancer Cytogenetics through Molecular Biology"
Department of Pathology, Brigham and Women's Hospital, Boston, MA, June 1984
"Use of Chromosomal In Situ Hybridization in Understanding Chromosomal Rearrangement"
Department of Pathology, Stanford University School of Medicine, Stanford, CA, Nov 1984
"Use of Chromosomal In Situ Hybridization in Understanding Chromosomal Rearrangement"
Department of Medicine, Baylor College of Medicine, Houston, TX, Dec 1984
1985
"Use of Chromosomal In Situ Hybridization in Understanding Chromosomal Rearrangement"
Department of Human Genetics, Medical College of Virginia, Richmond, VA, Feb 1985
"Understanding Chromosomal Rearrangement by Chromosomal In Situ Hybridization"
Department of Pathology, Tufts University School of Medicine, Boston, MA, Mar 1985
"Interpretation of Chromosomal Rearrangement by Chromosomal In Situ Hybridization"
Department of Pathology, The Beth Israel Hospital, Harvard Medical School, Jun 1985
1986
"Cytogenetic Changes in Hematologic Malignancies"
Department of Hematology, Massachusetts General Hospital, Boston, MA, Feb 1986
"Chromosomal Rearrangements in Association with Malignancies"
Course in Tumor Immunology, Immunology 713.7/209, Harvard Medical School, Boston, MA, Feb 1986 and Mar 1987
"Characterization of myc-Related Sequences"
Dana Farber Cancer Institute, Boston, MA, Jun 1986
"Chromosomal Mapping"
Workshop on In Situ Hybridization as a Clinical and Research Tool, Tufts University School of Medicine, Boston, MA, Oct 1986; Mar 1987; Mar 1988
1987
"Cancer Cytogenetics"
Specialty Conference in Pathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA, Oct 1987
"Chromosomal In Situ Hybridization: Usefulness in Gene Mapping and Interpretation of Chromosomal Rearrangements"
Pathology Grand Rounds, Department of Pathology, Brigham and Women's Hospital, Boston, MA, Nov 1987
1988
"Usefulness of Chromosomal In Situ Hybridization in Gene Mapping and in Interpretation of Chromosomal Rearrangements"
Mapping the Human Genome, Annual Meeting of the AAAS, Boston, MA, Feb 1988
"Usefulness of Chromosomal In Situ Hybridization in Gene Mapping and in Interpretation of Chromosomal Rearrangements"
Seminars in Cell and Molecular Biology, Beth Israel Hospital, Boston, MA, May 1988
"Molecular Approaches to Problems in Clinical Cytogenetics"
Meeting of the New England Society of Pathologists, Boston Museum of Science, Boston, MA, Nov 1988
1989
"MYCL2: A New Member of the MYC Multigene Family"
Department of Human Genetics, Medical College of Virginia, Richmond, VA, Mar 1989
"Chromosomal Lesions and Human Cancers"
Hematology Grand Rounds, The Medical Center of Delaware, Newark, DE, Apr 1989
1990
"Molecular Genetics in Prenatal Diagnosis"
Postgraduate Course in Maternal Fetal Medicine, The Ritz-Carlton Hotel, Boston, MA, Mar 1990
"Prenatal Diagnosis of Sex Chromosome Anomalies"
Genetics Division, The Children's Hospital, Boston, MA, Aug 1990
"Prenatal Diagnosis of Sex Chromosome Anomalies: Experience and Outcome at the Brigham and Women's Hospital (1985-1989)"
Perinatology Rounds, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Boston, MA, Sept 1990
"Cytogenetic Approaches to Understanding Cancer"
Symposium on Genetics, Biotechnology and Public Health, Galleria Conference Center, Boston, MA, Dec 1990
"Molecular Approaches to Cloning Genes in the Auditory System"
Eaton Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, MA, Dec 1990
1991
"Cytogenetic Analysis of POCs: The BWH Experience (1987-1990)"
Fertility and Endocrine Conference, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Boston, MA, Jun 1991
1992
"Application of Fluorescence In Situ Hybridization (FISH) in Solid Tumor Cytogenetics"
International Symposium on Molecular Cytogenetics, Resort at Squaw Creek, Lake Tahoe, CA, Feb 1992
"Cytogenetic Approaches to Understanding Human Cancers"
Course in Tumor Immunology, Harvard Medical School, Boston, MA, Feb 1992
"Application of Fluorescence In Situ Hybridization (FISH) in Solid Tumor Cytogenetics"
Collaborative Research, Inc., Waltham, MA, Feb 1992
"Application of FISH in Surgical Pathology: Role in Tumor Diagnosis"
Update in Surgical Pathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA, Feb 1992
"Cytogenetic Approaches to Understanding Human Cancers"
Course in Molecular Hematology, Cell Biology 214, Harvard Medical School, Boston, MA, Mar 1992
"Application of FISH in Clinical Cytogenetics"
Hematology Conference, Department of Hematology, Brigham and Women's Hospital, Boston, MA, Apr 1992
"Mapping the Human Genome"
1992 Outstanding Alumnus of the School of Basic Health Sciences, Medical College of Virginia, Richmond, VA, May 1992
"Cloning Genes Involved in Hearing"
Walter E. Nance Lectureship, Medical College of Virginia, Richmond, VA, May 1992
"Cloning Genes Involved in Hearing from a Human Fetal Cochlear cDNA Library"
The Molecular Biology of Hearing and Deafness, University of California San Diego, School of Medicine, San Diego, CA, May 1992
"Prenatal Diagnosis of Genetic Abnormalities: The Molecular Approach"
The Molecular Biology of Women's Health. Breast and Reproductive Tract. Department of Continuing Education, Harvard Medical School, Boston, MA, Sept 1992
1993
"Molecular Approaches to Understanding the Biology of Hearing"
Pathology Grand Rounds, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, Feb 1993
"Cytogenetic Approaches to Understanding Human Cancers"
Course in Molecular Hematology, Cell Biology 214, Harvard Medical School, Boston, MA, Apr 1993
"The FISH Technique: Applications to Diagnosis"
The Molecular Biology of Women's Health: Reproduction, Neoplasia and HIV. Department of Continuing Education, Harvard Medical School, Boston, MA, Oct 1993
"Use of Fluorescence In Situ Hybridization in Gene Mapping and Clinical Cytogenetics"
National Association of Biology Teachers. 1993 National Convention. Boston, MA, Nov 1993
"Molecular and Cytogenetic Studies of Uterine Leiomyomata"
Update in Diagnostic Pathology and Medicine Series, Department of Pathology, Baystate Medical Center, Springfield, MA, Dec 1993
1994
"Uses of Fluorescence In Situ Hybridization in Clinical Cytogenetics"
Renal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, Jan 1994
"Molecular and Cytogenetic Studies of Uterine Leiomyomata"
NICHD Workshop, Alternatives to Hysterectomy: Bench to Bedside, National Institutes of Health, Bethesda, MD, May 1994
"Identifying Candidate Genes"
Hereditary Deafness Workshop, 44th Annual meeting of the American Society of Human Genetics, Montréal, Quebec, Canada, October 1994
1995
"Isolation of Novel and Known Genes from a Human Fetal Cochlear cDNA Library Using Subtractive Hybridization and Differential Screening"
Annual meeting of the Association for Research in Otolaryngology, Tampa, FL, February 5, 1995
"Are Leiomyomas a Genetic Disease?"
42nd Annual Meeting of the Society for Gynecologic Investigation, Chicago, IL, March 17, 1995
"Genetics of Uterine Leiomyomata"
Millenium Pharmaceuticals, Inc., Boston, MA, April 21, 1995
"Many Tumors and Many Genes: Genetics of Uterine Leiomyomata"
William Lambert Richardson lecture, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, May 1, 1995
"Genetics of Hearing Loss"
Clinical Aspects of Speech and Hearing, Speech and Hearing Sciences Graduate Program, Massachusetts Eye and Ear Infirmary, Harvard Medical School, May 4, 1995
"Updates in Prenatal Diagnosis from the Antenatal Diagnostic Center"
Grand Rounds, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, June 14, 1995
"Cloning Genes Involved in Hearing: A Tissue Specific Library Approach" The second conference on The Molecular Biology of Hearing and Deafness, Bethesda, MD, October 8, 1995.
"Many Tumors and Many Genes: Genetics of Uterine Leiomyomata"
Department of Pathology, Harvard Medical School, October 11, 1995
"Many Tumors and Many Genes: Genetics of Uterine Leiomyomata"
Research Conference, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, November 1, 1995
"Architectural Factor HMGI-C Translocated in Uterine Leiomyomata and Other Benign Tumors"
Symposium on Chromosome 12 Genes in Cancer, Center for Human Genetics, Leuven, University of Leuven, Belgium, November 18, 1995
"Molecular Genetic Approaches to Cloning Genes Involved in Hearing"
Grand Rounds, Massachusetts Eye and Ear Infirmary, Harvard Medical School, December 7, 1995
1996
"Many Tumors and Many Genes: Genetics of Uterine Leiomyomata"
Session on Reproductive and Developmental Biology: Innovations in Fertility, AAAS Annual Meeting and Science Innovation Exposition, Baltimore, MD, February 12, 1996
"Sex Chromosome Disorders"
Advanced Human Genetics Seminar Series, American Board of Medical Genetics Training Program, Harvard Medical School, March 5, 1996
"Many Tumors and Many Genes: Genetics of Uterine Leiomyomata"
Seminar, Department of Human Genetics, University of Michigan, Ann Arbor, MI, April 21, 1996
"Genetics Disorders of the Ear"
Basic Sciences Course for Otolaryngology Residents, Massachusetts Eye and Ear Infirmary, Harvard Medical School, April 29, 1996
"Many Tumors and Many Genes: Genetics of Uterine Leiomyomata"
Seminar Program in Molecular Genetics, Department of Molecular Genetics, Albert Einstein College of Medicine of Yeshiva University, Bronx, NY, May 16, 1996
"Cytogenetics of Uterine Fibroids"
Grand Rounds in Clinical Pathology, Department of Pathology, Massachusetts General Hospital, Harvard Medical School, May 23, 1996
"Are Uterine Leiomyomata a Genetic Disease?"
8th Annual NICHD Aspen Conference on Maternal-Fetal-Neonatal-Reproductive Medicine, The Given Biomedical Institute, Aspen, CO, August 24, 1996
"Identifying Genes Involved in Hearing"
Research Conference, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, November 13, 1996
"Genetics of Uterine Leiomyomata"
Endocrine Conference, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, December 10, 1996
1997
"Many Tumors and Many Genes: Genetics of Uterine Leiomyomata"
Warner-Lambert/Parke-Davis Award Lecture, American Society of Investigative Pathology, Experimental Biology 97 Meeting, New Orleans, April 7, 1997
"Many Tumors and Many Genes: Genetics of Uterine Leiomyomata"
Faculte de Medecine, Nice, France, April 23, 1997
"Many Tumors and Many Genes: Genetics of Uterine Fibroids"
Department of Pathology Annual Research Retreat, Harvard Medical School, North Falmouth, MA, June 23, 1997
"Many Tumors and Many Genes: Genetics of Uterine Leiomyomata"
National Institute of Environmental Health Sciences, Research Triangle Park, NC, July 8, 1997
"Many Tumors and Many Genes: Genetics of Uterine Leiomyomata"
Genetics Rounds, New England Medical Center, Boston, MA, July 21, 1997
"Cloning Genes Involved in Hearing"
Hearing and Chemical Senses Seminar, Kresge Hearing Research Institute, University of Michigan, Ann Arbor, August 4, 1997
1998
"Many Tumors and Many Genes: Genetics of Uterine Leiomyomata"
Renal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, April 30, 1998
"HMGIC and HMGIY Rearrangements as Secondary Events in the Genesis of Uterine Leiomyomas: Evidence for the Genetic Basis of Fibroids"
First International Workshop on the Role of High Mobility Group Proteins in Human Disease, Bremen, Germany, June 16, 1998
"Chromosomes in Gametogenesis and Cell Division"
The 39th Short Course in Medical and Experimental Mammalian Genetics, The Jackson Laboratory, Bar Harbor, ME, July 21, 1998
"Chromosome Aberrations: Molecular Cytogenetics"
The 39th Short Course in Medical and Experimental Mammalian Genetics, The Jackson Laboratory, Bar Harbor, ME, July 21, 1998
"Clinical and Molecular Genetics of Deafness"
The 39th Short Course in Medical and Experimental Mammalian Genetics, The Jackson Laboratory, Bar Harbor, ME, July 31, 1998
"Tuning Into the Genetics of Hearing"
The 48th annual meeting of the American Society of Human Genetics, Denver, CO, Oct. 28, 1998
"Cloning Genes Involved in Hearing"
Department of Biomedical Engineering, Boston University, Boston, MA, Nov. 19, 1998
1999
"Cloning Genes Involved in Hearing"
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, Feb. 16, 1999
"Tuning into the Genetics of Hearing"
Grand Rounds, Department of Medicine, Children's Hospital, Boston, MA, Feb. 24, 1999
"Of Genes and Genomics"
BWH Research Retreat, BankBoston Conference Center, Waltham, MA, Mar. 16, 1999
"Many Tumors and Many Genes: Genetics of Uterine Leiomyomata"
Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA, Apr. 16, 1999
"Many Tumors and Many Genes: Genetics of Uterine Leiomyomata"
Cardiovascular Research Seminar Series, Department of Medicine, Brigham and Women's Hospital, Boston, MA, May 10, 1999
"Tuning Into the Genetics of Hearing"
BBS Minisymposium on Human Genetics, Harvard Medical School, Boston, MA, May 19, 1999
"Many Tumors and Many Genes: Genetics of Uterine Leiomyomata"
Molecular Medicine Seminar Series, Center for Molecular Medicine, The School of Medicine of the University of Connecticut Health Center, Farmington, CT, May 24, 1999
"Genetics of Hearing"
Advanced Human Genetics Seminar Series, American Board of Medical Genetics Training Program, Harvard Medical School, May 25, 1999
"Many Tumors and Many Genes: Genetics of Uterine Leiomyomata"
Fanger Lecture, Department of Pathology and Laboratory Medicine, Brown University School of Medicine, Providence, RI, June 4, 1999
"Where Are The Genes and What Are They Doing? - Mapping of Genes in the Human Cochlea"
Sixth Annual Research Symposium at the 14th International SHHH Convention, New Orleans, LA, June 30, 1999
"Genetic Approaches to Understanding the Biology of Uterine Fibroids"
Women's Health and the Environment: the Next Century, Advances in Uterine Leiomyoma Research, National Institute of Environmental Health Sciences, Research Triangle Park, NC, October 7, 1999
"Fibroids: Facts, Fiction and the Future"
Robert C. Knapp, M.D. Lecture in Gynecology, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Boston, MA, October 26, 1999
"The Future of Treatments for Uterine Leiomyomata: Will Genetic Studies Impact Therapy?"
Grand Rounds, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Boston, MA, October 27, 1999
"Cloning Genes Involved in Hearing"
Molecular Mechanisms of Hearing and Balance Seminar Series, Harvard Center for Hereditary Hearing Loss, Brigham and Women's Hospital, Boston, MA, December 6, 1999
2000
"Cloning Genes Involved in Hearing"
Department of Human Genetics, University of California at Los Angeles, Los Angeles, CA, January 10, 2000
“Gene Expression Analysis of Uterine Leiomyomata and Myometrium Using Oligonucleotide Microarrays: A Model System for the Evaluation of Genetic Effects on Gene Expression”
The International Workshop on Chromosomes in Solid Tumors, Tucson, AZ, Jan. 31, 2000
"Cloning Genes Involved in Hearing"
Interdisciplinary Genetics Ph.D. Program, University of Iowa, Iowa City, IA, February 17, 2000
"Cloning Genes Involved in Hearing"
Department of Otolaryngology, Boston University School of Medicine, Boston, MA, April 6, 2000
“Gene Expression Analysis of Uterine Leiomyomata and Myometrium Using Oligonucleotide Microarrays: A Model System for the Evaluation of Genetic Effects on Gene Expression”
Workshop on The Role of HMG Proteins in Chromatin Structure, Gene Expression and Neoplasia, National Institutes of Health, Bethesda, MD, May 2, 2000
"Many Tumors and Many Genes: Genetics of Uterine Leiomyomata"
Department of Human Genetics, Virginia Commonwealth University, Richmond, VA, June 6, 2000
“Cloning Genes Involved in Hearing”
University of Alabama School of Medicine, Birmingham, AL, June 12, 2000
“Genomic Approaches to Understanding the Biology of Uterine Leiomyomata”
Cancer Genomics Journal Club, Dana Farber Cancer Institute, Boston, MA, June 28, 2000
“Guidelines to Success in Academia”
Fourth Annual Reproductive Scientist Development Program Scholars’ Research Conference, Santa Fe, NM, September 16, 2000
“Cloning Genes Involved in Hearing”
Indiana University School of Medicine, Indianapolis, IN, November 29, 2000
"Many Tumors and Many Genes: Genetics of Uterine Leiomyomata"
Department of Medical and Molecular Genetics, Indianapolis, IN, November 29, 2000
2001
“A Return on Your Investment in the Human Genome Project: The Developmental Genome Anatomy Project”
Coriell Institute for Medical Research, Camden, NJ, February 21, 2001
“Genomics Resources Applied in the Clinical Cytogenetics Lab”
Banbury Conference “Integrating Genomics Technologies in Healthcare: Practice and Policy Challenges”, Cold Spring Harbor, NY, February 27, 2001
“Many Tumors and Many Genes: Genetics of Uterine Leiomyomata”
Genetics Rounds, Division of Genetics, New England Medical Center, Boston, MA, April 2, 2001
“DGAP: Gene Cloning from Balanced Chromosomal Rearrangements”
The 7th Annual NERGG Education Meeting, Baystate Medical Center, Springfield, MA, April 28, 2001
“Tuning Into the Genetics of Hearing”
Department of Medical Genetics, University of Alberta, Edmonton, Alberta, May 9, 2001
“Why Clone Genes for Hearing?”
“Listen to Your Genes: Genetics of Childhood Hearing Loss”, The Longwood Seminars at Harvard Medical School, Boston, MA, May 29, 2001
2002
“Many Tumors and Many Genes: Genetics of Uterine Leiomyomata”
Grand Rounds, Department of Obstetrics and Gynecology, Georgetown University Hospital, Washington, DC, March 27, 2002
“Genetics of Uterine Leiomyomata”
Grand Rounds, Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX, May 1, 2002
“Are Fusion Transcripts Involving HMGA2 a Common Molecular Mechanism in Uterine Leiomyomata with Rearrangements in 12q15?”
The Third International Workshop on HMGA Proteins in Cell Differentiation and Transformation, Napoli, Italy, May 23-24, 2002
“At the Speed of Sound: Gene Discovery in the Auditory System”
Columbia University College of Physicians & Surgeons, New York, NY, September 26, 2002
“Cloning Genes Involved in Hearing”
Autoimmunity of Cochlea 2002 Update: Biology of Hearing and Hearing Loss in Autoimmune Ear Disease, Genoa, Italy, November 1, 2002
“Many Tumors and Many Genes: Genetics of Uterine Leiomyomata”
University of Cagliari, Cagliari, Italy, November 4, 2002
2003
“Cloning Genes Involved in Hearing”
Human Medical Genetics Program, University of Colorado Health Sciences Center, Denver, February 20, 2003
“Many Tumors and Many Genes: Genetics of Uterine Leiomyomata”
Department of Human Genetics, University of California at Los Angeles, Los Angeles, CA, August 29, 2003
“Many Tumors and Many Genes: Genetics of Uterine Leiomyomata”
Pathology Presents Seminar, Department of Pathology, University of Washington School of Medicine, Seattle, WA, October 8, 2003
“Many Tumors and Many Genes: Genetics of Uterine Leiomyomata”
Department of Human Genetics, University of Michigan, Ann Arbor, MI, October 2, 2003
Grand Rounds, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women’s Hospital, Boston, MA, November 12, 2003
2004
"The Developmental Genome Anatomy Project (DGAP): A Cytogenetic Approach to Gene Discovery in the Genome Era"
Molecular and Cellular Biology Symposium, "Forward Genetics in the Post-Genome Era", University of Arizona, Tucson, AZ, April 9-10, 2004
“Cytogenetic Methods”
Laboratory Medicine Lecture Series, Beth Israel Deaconess Hospital, Boston, MA, May 3, 2004
“Chromosomal Disorders”
Laboratory Medicine Lecture Series, Beth Israel Deaconess Hospital, Boston, MA, May 10, 2004
“Cytogenetic Approaches to Gene Discovery in the Genome Era”
Armenise-Harvard Foundation 8th Annual Symposium, "Cancer Genomics", Siena, Italy, May 21-24, 2004
“Cytogenetic Approaches to Gene Discovery in the Genome Era”
10th Anniversary of the Chronic Care Center Medical Meeting, Beirut, Lebanon, June 17-19, 2004
“Genetic Liabilities for Uterine Leiomyomata”
Reproductive Endocrinology and Infertility Seminar Series, Department of Obstetrics and Gynecology, Brigham and Women’s Hospital, Boston, MA, November 16, 2004
2005
“Genetic Links”
Advances in Uterine Leiomyoma: 2nd NIH International Congress, National Institutes of Health, Bethesda, Maryland, February 24-25, 2005
“Genetics and Hearing Disorders: A Paradigm for Complex Genetic Disease and Newborn Screening”
Peking Union Medical College, Beijing, China, March 28, 2005
“Cytogenetic Approaches to Gene Discovery in the Genome Era: The Developmental Genome Anatomy Project”
Peking Union Medical College, Beijing, China, March 28, 2005
“Cytogenetic Approaches to Gene Discovery in the Genome Era: The Developmental Genome Anatomy Project”
Department of Human Genetics, Mount Sinai Medical School, New York, NY, May 6, 2005
“Cytogenetic Approaches to Gene Discovery in the Genome Era”
Department of Pathology, Harvard Medical School, Summer Graduate Programs Retreat, North Falmouth, MA, June 20-21, 2005
“Cytogenetic Approaches to Gene Discovery in the Genome Era”
DECIPHER Symposium, The Sanger Center, Hinxton Cambridge, UK, June 23-25, 2005
“Cloning Genes Involved in Hearing”
Department of Otolaryngology, The Cleveland Clinic, Cleveland, OH, October 19, 2005
“From Gene Discovery in the Auditory System to Genetic testing in Newborns: Progress at the Speed of Sound”
Northeast Ohio Otolaryngology Society, Case Western Reserve University affiliated Hospitals and The Cleveland Clinic, Cleveland, OH, October 19, 2005
“From Gene Discovery in the Auditory System to Genetic testing in Newborns: Progress at the Speed of Sound”
Genetic and Translational Research on Sensorineural Hearing Loss: A Special Symposium, Albert Einstein College of Medicine and Jacobi Medical Center, New York, NY, November 14, 2005
2006
“Genetic Analysis of the Most Common Tumor on the Planet: The Story of Uterine Fibroids”
Grand Rounds, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women’s Hospital, Boston, MA, February 1, 2006
“Genetic Analysis of the Most Common Tumor on the Planet: The Story of Uterine Fibroids”
Department of Cellular and Structural Biology Seminar Series, The University of Texas Health Science Center at San Antonio, TX, February 28, 2006
“The Brigham and Women’s Hospital Family History Project”
Honors Convocation, MGH Institute of Health Professions, Charlestown, MA, May 12, 2006
“What is the final answer? Experience with genome-wide aCGH testing at the Brigham and Women’s and Massachusetts General Hospitals”
The DECIPHER Symposium, The Sanger Center, Hinxton, England, June 18-20, 2006
“From Gene Discovery in the Auditory System to Genetic Testing in Newborns: A Silent Revolution”
Pediatric Grand Rounds, New York University, New York City, NY, July 25, 2006
“Genetic Analysis of the Most Common Tumor on the Planet: The Story of Uterine Fibroids”
Schering AG, Berlin, Germany, August 30, 2006
“Cytogenetic Approaches to Gene Discovery in the Genome Era: The Developmental Genome Anatomy Project”
NeoGenomics, Ft. Myers, FL, September 8, 2006
“From Gene Discovery in the Auditory System to Genetic Testing in Newborns: A Silent Revolution”
Symposium on Hearing Development and Hearing Loss, Salt Lake City, UT, September 15, 2006
2007
“From Gene Discovery in the Auditory System to Genetic Testing in Newborns: A Silent Revolution”
University of Nebraska, Omaha, NE, April 17, 2007
“Genetic Analysis of the Most Common Tumor on the Planet: The Story of Uterine Fibroids”
Grand Rounds, Department of Obstetrics and Gynecology, Boston Medical Center, Boston, MA, April 25, 2007
“The Developmental Genome Anatomy Project: Structural Analyses of Breakpoints and Genomes”
The DECIPHER Symposium, The Sanger Center, Hinxton, England, May 16-18, 2007
“Finding Genes for Fibroids”
Reproductive Endocrinology and Infertility Seminar Series, Department of Obstetrics and Gynecology, Brigham and Women’s Hospital, Boston, MA, May 22, 2007
“Lessons from the Analysis of Apparently Balanced Chromosomal Rearrangements: the Developmental Genome Anatomy Project (DGAP) Experience”
Agilent Microarray CGH Symposium, Harvard Medical School, Boston, MA, May 29, 2007
“Human Genetics of Hearing and Deafness”
Biology of the Inner Ear, Marine Biological Laboratory, Woods Hole, MA, August 27, 2007
“The Developmental Genome Anatomy Project (DGAP): A Cytogenetic Approach to Gene Discovery in the Genome Era”
Seminar, Department of Human Genetics, Emory University, Atlanta, GA, December 10, 2007
2008
“The Developmental Genome Anatomy Project (DGAP): A Cytogenetic Approach to Gene Discovery in the Genome Era”
Reproductive Endocrine Lecture Series, Massachusetts General Hospital, Boston, MA, January 29, 2008
“Lessons from the Analysis of Apparently Balanced Chromosome Rearrangements: the Developmental Genome Anatomy Project (DGAP)”
American College of Medical Genetics March of Dimes Symposium, Phoenix, AZ, March 14, 2008
“Genetic Analysis of the Most Common Tumor on the Planet: The Story of Uterine Fibroids”
Alicia Showalter Reynolds Memorial Lectureship, Johns Hopkins University School of Medicine, Baltimore, MD, April 15, 2008
“The Developmental Genome Anatomy Project (DGAP): A Cytogenetic Approach to Gene Discovery in the Genome Era”
Genetics Rounds, Tufts Medical Center, Boston, MA, April 28, 2008
“Cloning Genes Involved in Hearing”
Visiting Scientist, Eaton-Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, MA, May 30, 2008
“Cloning Genes Involved in Hearing”
Visiting Scientist, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia, June 10, 2008
“Genetic Analysis of the Most Common Tumor on the Planet: The Story of Uterine Fibroids”
Visiting Professor Series, Department of Pathology, University of California Los Angeles, June 26, 2008
“The Developmental Genome Anatomy Project (DGAP): A Cytogenetic Approach to Gene Discovery in the Genome Era”
David L. Rimoin Lecture in Genetics Education, University of California Los Angeles Medical Genetics Graduation, June 27, 2008
“Genetic Analysis of the Most Common Tumor on the Planet: The Story of Uterine Fibroids”
Seminar, Wyeth, Collegeville, PA, July 15, 2008
“The Developmental Genome Anatomy Project (DGAP): A Cytogenetic Approach to Gene Discovery in the Genome Era”
International Conference on Frontiers of Dental and Craniofacial Research, Beijing, China, November 1, 2008
“The Developmental Genome Anatomy Project (DGAP): A Cytogenetic Approach to Gene Discovery in the Genome Era”
The Raphael Recanati Genetic Institute, Rabin Medical Center, Petach Tikva, Israel, November 20, 2008
“The Developmental Genome Anatomy Project (DGAP): A Cytogenetic Approach to Gene Discovery in the Genome Era”
Renal Division Seminar Series, Brigham and Women’s Hospital, Boston, MA, December 16, 2008
2009
“Personalized Medicine and Genetics”
Ob/Gyn Resident Seminar Series, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women’s Hospital, Boston, MA, January28, 2009
“Genetic Analysis of the Most Common Tumor on the Planet: The Story of Uterine Fibroids”
Pathology Seminar Series, Department of Pathology, Beth Israel Deaconness Hospital, Boston, MA, February 20, 2009
“Genetic Analysis of the Most Common Tumor on the Planet: The Story of Uterine Fibroids”
Reproductive Endocrinology and Infertility Seminar Series, Department of Obstetrics and Gynecology, Brigham and Women’s Hospital, Boston, MA, February 24, 2009
“Tuning into Personalized Medicine”
HST Seminar Series on Biomarkers, Massachusetts Institute of Technology, Cambridge, MA, February 26, 2009
“The Developmental Genome Anatomy Project (DGAP): A Cytogenetic Approach to Gene Discovery in the Genome Era”
Department of Pathology, Boston University School of Medicine, Boston, MA, April 10, 2009
“Genetic Analysis of the Most Common Tumor on the Planet: The Story of Uterine Fibroids”
GeneMappers 2009, Katoomba, Australia, April 14, 2009
“Historical Perspective on Human Gene Mapping Workshops”
GeneMappers 2009, Katoomba, Australia, April 16, 2009
“The Tumor Genome Anatomy Project (TGAP): A Cytogenetic Approach to Gene Discovery in the Genome Era”
Cancer Cytogenetics Conference 2009, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia, May 27, 2009
“Genetic Analysis of the Most Common Tumor on the Planet: The Story of Uterine Fibroids”
Cancer Cytogenetics Conference 2009, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia, May 27, 2009
BIBLIOGRAPHY:
Original Reports:
1. Casamassima AC, Morton CC, Caldwell RJ, Kelley TE, Kodroff MB, Nance WE, Wolf B: Spondylothoracic dysplasia with anal and urogenital anomalies in a Mennonite sibship. Amer. J. Med. Genet. 1981; 8:117-127.
2. Morton CC, Cantor RM, Corey LA, Nance WE: A genetic analysis of taste threshold for phenylthiocarbamide. Acta Genet. Med. Gemellol. 1981; 30:51-57.
3. Morton CC, Corey LA, Nance WE, Brown JA: Quinacrine mustard and nucleolar organizer region heteromorphisms in twins. Acta Genet. Med. Gemellol. 1981; 30:39-49.
4. Bieber FR, Nance WE, Morton CC, Brown JA, Redwine FO, Jordan RL, Mohanakumar T: Genetic studies of an acardiac monster: Evidence for polar body twinning in man. Science 1981; 213:775-777.
5. Kirsch IR, Morton CC, Nakahara K, Leder P: Human immunoglobulin heavy chain genes map to a region of translocation in malignant B lymphocytes. Science 1982; 216:301-303.
6. Taub R, Kirsch I, Morton C, Lenoir G, Swan D, Tronick S, Aaronson S, Leder P: Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells. Proc. Natl. Acad. Sci. USA 1982; 79:7837-7841.
7. Morton CC, Brown JA, Holmes WM, Nance WE, Wolf B: Stain intensity of human nucleolus organizer region reflects incorporation of uridine into mature ribosomal RNA. Exp. Cell Res. 1983; 145:405-413.
8. Bonner TI, O'Brien SJ, Nash WG, Rapp UR, Morton CC, Leder P: The human homologs of the raf(mil) oncogene are located on human chromosomes 3 and 4. Science 1984; 223:71-74.
9. Morton CC, Taub R, Diamond A, Lane M‑A, Cooper GM, Leder P: Mapping of the human Blym-1 transforming gene activated in Burkitt lymphomas to chromosome 1. Science 1984; 223:173-175.
10. Morton CC, Kirsch IR, Nance WE, Evans GA, Korman AJ, Strominger JL: Orientation of loci within the human major histocompatibility complex by chromosomal in situ hybridization. Proc. Natl. Acad. Sci. USA 1984; 81:2816-2820.
11. Kurnit DM, Neve RL, Morton CC, Bruns GAP, Ma NSF, Cox DM, Klinger HP: Recent evolution of non-ribosomal DNA sequence homology in the pericentromeric regions of human acrocentric chromosomes. Cytogenet. Cell Genet. 1984; 38:99-105.
12. Morton CC, Kirsch IR, Taub RA, Orkin SH, Brown JA: Localization of the beta-globin gene by chromosomal in situ hybridization. Am. J. Hum. Genet. 1984; 36:576-585.
13. Latt SA, Kurnit DM, Bruns GP, Schreck RR, Morton CC, Kunkel LM, Lalande M, Aldridge J, Neve R, Tantravahi U, Kanda N, Lindner G, Meryash D: Molecular genetic approaches to human diseases involving mental retardation. Am. J. Ment. Def. 1984; 88:561-571.
14. Kirsch IR, Brown JA, Lawrence J, Korsmeyer SJ, Morton CC: Translocations that highlight chromosomal regions of differentiated activity. Cancer Genet. Cytogenet. 1985; 18:159-171.
15. Morton CC, Duby AD, Eddy RL, Shows TB, Seidman JG: Genes for beta chain of human T-cell antigen receptor map to regions of chromosomal rearrangement in T-cells. Science 1985; 228:582-585.
16. Michelson AM, Bruns GAP, Morton CC, Orkin SH: The human phosphoglycerate kinase multigene family: HLA-associated sequences and an X-linked locus containing a processed pseudogene and its functional counterpart. J. Biol. Chem. 1985; 260:6982-6992.
17. Dryja TP, Morton CC: Mapping of seven polymorphic loci on human chromosome 13 by in situ hybridization. Hum. Genet. 1985; 71:192-195.
18. Murre C, Waldmann RA, Morton CC, Bongiovanni KF, Waldmann TA, Shows TB, Seidman JG: Human gamma chain genes are rearranged in leukemic T-cells and map to the short arm of chromosome 7. Nature 1985; 316:549-552.
19. Berliner N, Duby AD, Morton CC, Seidman JG, Leder P: Detection of a frequent restriction fragment length polymorphism in the human T-cell antigen receptor beta chain locus: a potential diagnostic tool. J. Clin. Invest. 1985; 76:1283-1285.
20. Morton CC, Brown JA, Kirsch IR, Evans GA, Mohanakumar K, Nance WE: Detection and localization of an extra HLA locus in a karyotypically normal male by chromosomal in situ hybridization. Clin. Genet. 1986; 29:62-72.
21. Morton CC, Byers MG, Nakai H, Bell GI, Shows TB: Human chromosome location of the genes for insulin-like growth factor 1, insulin-like growth factor 2, and epidermal growth factor. Cytogenet. Cell Genet. 1986; 41:245-249.
22. Max EE, McBride WO, Morton CC, Robinson MA: The human J chain gene: chromosomal localization and associated restriction fragment length polymorphisms. Proc. Natl. Acad. Sci. USA 1986; 83:5592-5596.
23. Harris P, Morton CC, Guglielmi P, Li F, Kelly K, Leder P, Latt SA: Mapping by chromosome sorting of several gene probes, including c-myc, to the derivative chromosomes of a 3;8 translocation associated with familial renal cancer. Cytometry 1986; 7:589-594.
24. Marlin SD, Morton CC, Anderson DC, Springer TA: LFA-1 immunodeficiency disease: Definition of the genetic defect and chromosomal mapping of alpha and beta subunits by complementation in hybrid cells. J. Exp. Med. 1987; 164:855-867.
25. Weis JH, Morton CC, Bruns GAP, Weis JJ, Klickstein LB, Wong WW, Fearon DT: Definition of a complement receptor locus: The genes encoding the C3b receptor and the C3d/Epstein Barr virus receptor map to human chromosome 1. J. Immunol. 1987; 138:312-315.
26. Glimcher LH, Polla BS, Morton CC, McKean DJ: Murine class II (Ia) molecules associate with human invariant chain. J. Immunol. 1987; 138:1519-1523.
27. Spies T, Morton CC, Nedospasov SA, Shakhov AN, Korobko VG, Fiers W, Pious D, Strominger JL: The tumor necrosis factor (TNF) alpha and beta genes are linked to the human major histocompatibility complex (MHC). Proc. Natl. Acad. Sci. USA 1986; 83:8699-8702.
28. Gold DP, Van Dongen JJM, Morton CC, Bruns GAP, Van Den Elsen P, Geurts Van Kessel AHM, Terhorst C: The gene encoding the epsilon subunit of the T3/T-cell receptor complex maps to chromosome 11 in humans and to chromosome 9 in mice. Proc. Natl. Acad. Sci. USA 1987; 84:1664-1668.
29. Ralph SJ, Thomas ML, Morton CC, Trowbridge IS: Structural variants of human T200 glycoprotein (leukocyte-common antigen). EMBO J. 1987; 6:1251-1257.
30. Arbiser JL, Morton CC, Bruns GAP, Majzoub JA: Human corticotropin releasing hormone gene is located on the long arm of chromosome 8. Cytogenet. Cell Genet. 1988; 47:113-116.
31. Bonthron DT, Morton CC, Orkin SH, Collins T: Platelet-derived growth factor A chain: Gene structure, chromosomal localization and basis for alternative mRNA splicing. Proc. Natl. Acad. Sci. USA 1988; 85:1492-1496.
32. Graninger W, Goldman PL, Morton CC, O'Brien SJ, Korsmeyer SJ: The kappa deleting element: Germline and rearranged, duplicated and dispersed forms. J. Exp. Med. 1988; 167:488-501.
33. Kwiatkowski DJ, Westbrook CA, Bruns GAP, Morton CC: Localization of gelsolin proximal to c-abl on chromosome 9. Am. J. Hum. Genet. 1988; 42:565-572.
34. Bloch DB, Bloch KD, Iannuzzi M, Collins FS, Neer EJ, Seidman JG, Morton CC: The gene for the alphai1 subunit of human guanine nucleotide binding protein maps near the cystic fibrosis locus. Am. J. Hum. Genet. 1988; 42:884-888.
35. Corbi AL, Larson RS, Kishimoto TK, Springer TA, Morton CC: Chromosomal location of the genes encoding the leukocyte adhesion receptors LFA-1, Mac-1 and p150,95. Identification of a gene cluster involved in cell adhesion. J. Exp. Med. 1988; 167:1597-1607.
36. Phelan MC, Morton CC, Stevenson RE, Watkins PC, Tanzi RE, Stewart GD, Gusella JF, Amos JA: Molecular and cytogenetic characterization of a de novo t(5p;21q) in a patient previously diagnosed as monosomy 21. Am. J. Hum. Genet. 1988; 43:511-519.
37. Shiang R, Murray JC, Morton CC, Buetow KH, Wasmuth JJ, Olney AH, Sanger WG, Goldberger G: Mapping of the human complement factor I gene to 4q25. Genomics 1989; 4:82-86.
38. Morton CC, Nussenzweig MC, Sousa R, Sorenson GD, Pettengill OS, Shows TB: Mapping and characterization of an X-linked processed gene related to MYCL1. Genomics 1989; 4:367-375.
39. Beier DR, Morton CC, Leder A, Wallace R, Leder P: Perinatal lethality (ple): a mutation caused by integration of a transgene into distal mouse chromosome 15. Genomics 1989; 4:498-504.
40. Fletcher JA, Aster JC, Morton CC: Association of trisomy 8 and squamous differentiation in an endometrial adenocarcinoma. Cancer Genet. Cytogenet. 1989; 39:185-189.
41. Tepler I, Morton CC, Shimizu A, Holcombe RF, Eddy R, Shows TB, Leder P: The gene for the human mast cell high-affinity IgE receptor alpha chain: chromosomal localization to 1q21-q23 and RFLP analysis. Am. J. Hum. Genet. 1989; 45:761-765.
42. Fletcher JA, Lipinski KK, Weidner N, Morton CC: Complex cytogenetic aberrations in a well-differentiated chondrosarcoma. Cancer Genet. Cytogenet. 1989; 41:115-121.
43. Band V, Zajchowski D, Stenman G, Morton CC, Kulesa V, Connolly J, Sager R: A newly established metastatic breast tumor cell line with integrated amplified copies of ERBB2 and double minute chromosomes. Genes Chromosomes Cancer 1989; 1:48-58.
44. Sastry K, Herman GA, Day L, Deignan E, Bruns G, Morton CC, Ezekowitz RAB: The human mannose binding protein gene. Exon structure reveals its evolutionary relationship to a human pulmonary surfactant gene and localization to chromosome 10. J. Exp. Med. 1989; 170:1175-1189.
45. Kwiatkowski DJ, Aklog L, Ledbetter DH, Morton CC: Identification of the functional profilin gene, its localization to chromosome subband 17p13.3, and demonstration of its deletion in some patients with Miller- Dieker syndrome. Am. J. Hum. Genet. 1990; 46:559-567.
46. Zutter M, Hockett RD, Roberts CWM, McGuire EA, Bloomstone J, Morton CC, Deaven LL, Crist WM, Carroll AJ, Korsmeyer SJ: The t(10;14)(q24;q11) of T‑cell acute lymphoblastic leukemia juxtaposes the delta T-cell receptor with TCL3, a conserved and activated locus at 10q24. Proc. Natl. Acad. Sci. USA 1990; 87:3161-3165.
47. Sabina RL, Morisaki T, Clarke P, Eddy R, Shows TB, Morton CC, Holmes EW: Characterization of the human and rat myoadenylate deaminase genes. J. Biol. Chem. 1990; 265:9423-9433.
48. Fletcher JA, Morton CC, Pavelka K, Lage JM: Chromosome aberrations in uterine smooth muscle tumors: Potential diagnostic relevance of cytogenetic instability. Cancer Res. 1990; 50:4092-4097.
49. Solomon SD, Geisterfer-Lowrance AAT, Vosberg H-P, Hiller G, Jarcho JA, Morton CC, McBride OW, Mitchell AL, Bale AE, McKenna W, Seidman JG, Seidman CE: A locus for familial hypertrophic cardiomyopathy is closely linked to the cardiac myosin heavy chain genes, CRI-L436 and CRI-L329 on chromosome 14 at q11-q12. Am. J. Hum. Genet. 1990; 47:389-394.
50. Irving SG, Zipfel PF, Balke J, McBride OW, Morton CC, Burd PR, Siebenlist U, Kelly K: Two inflammatory mediator cytokine genes are closely linked and variably amplified on chromosome 17q. Nucleic Acids Res. 1990; 18:3261-3270.
51. Weremowicz S, Fox EA, Morton CC, Vallee BL: The placental ribonuclease inhibitor (PRI) gene is located on chromosome sub-band 11p15.5. Genomics 1990; 8:717-721.
52. Weremowicz S, Fox EA, Morton CC, Vallee BL: Localization of the human angiogenin gene to chromosome band 14q11, proximal to the T cell receptor alpha/delta locus. Am. J. Hum. Genet. 1990; 47:973-981.
53. Ray RA, Morton CC, Lipinski KK, Corson JM, Fletcher JA: Cytogenetic evidence of clonality in a case of pigmented villonodular synovitis. Cancer 1991; 67:121-125.
54. Fletcher JA, Kozakewich HP, Pavelka K, Grier HE, Korf B, Morton CC: Consistent cytogenetic aberrations in hepatoblastoma: A common pathway of genetic alterations in embryonal liver and skeletal muscle malignancies? Genes Chromosomes Cancer 1991; 3:37-43.
55. Maas RL, Jepeal LI, Elfering SL, Holcombe RF, Morton CC, Eddy RL, Byers MG, Shows TB, Leder P: A human gene homologous to the formin gene residing at the murine limb deformity locus: chromosome localization and RFLPs. Am. J. Hum. Genet. 1991; 48:687-695.
56. Fletcher JA, Kozakewich HP, Hoffer FA, Lage JM, Weidner N, Tepper RI, Pinkus GS, Morton CC, Corson JM: Diagnostic relevance of clonal cytogenetic aberrations in malignant soft-tissue tumors. N. Engl. J. Med. 1991; 324:436-443.
57. Rein MS, Friedman AJ, Barbieri RL, Pavelka K, Fletcher JA, Morton CC: Cytogenetic abnormalities in uterine leiomyomata. Obstet. Gynecol. 1991; 77:923-926.
58. Fletcher JA, Gibas Z, Donovan K, Perez-Atayde A, Genest D, Morton CC, Lage JM: Ovarian granulosa-stromal cell tumors are characterized by trisomy 12. Am. J. Pathol. 1991; 138:515-520.
59. Fletcher JA, Pinkus GS, Weidner N, Morton CC: Lineage-restricted clonality in biphasic solid tumors: demonstration in pulmonary chondroid hamartoma and breast adenofibroma. Am. J. Pathol. 1991; 138:1199-1207.
60. Robertson NG, Pomponio RJ, Mutter GL, Morton CC: Testis-specific expression of the human MYCL2 gene. Nucleic Acids Res. 1991; 19:3129-3137.
61. White JJ, Ledbetter DB, Eddy RL, Shows TB, Stewart DA, Nuell MJ, Friedman V, Wood CM, Owens GA, McClung JK, Danner DB, Morton CC: Assignment of the human prohibitin gene to chromosome 17 and identification of a DNA polymorphism. Genomics 1991; 11:228-230.
62. Rollins BJ, Morton CC, Ledbetter DH, Eddy RL, Shows TB: Assignment of the human small inducible cytokine A2 gene, SCYA2 (Encoding JE or MCP-1), to 17q11.1-12: Evolutionary relatedness of cytokines clustered at the same locus. Genomics 1991; 10:489-492.
63. Fletcher JA, Henkle C, Atkins L, Rosenberg AE, Morton CC: Trisomy 5 and trisomy 7 are nonrandom aberrations in pigmented villonodular synovitis: Confirmation of trisomy 7 in uncultured cells. Genes Chromosomes Cancer 1991; 4:1-3.
64. Magovcevic I, Ang S-L, Seidman JG, Tolman CJ, Neer EJ, Morton CC: Regional localization of the human G protein ai2 (GNAI2) gene: Assignment to 3p21 and a related sequence (GNAI2L) to 12p12-p13. Genomics 1992; 12:125-129.
65. Albritton LM, Bowcock AM, Eddy RL, Morton CC, Tseng L, Farrer LA, Cavalli-Sforza LL, Shows TB, Cunningham JM: The human cationic amino acid transporter (ATRC1): Physical and genetic mapping to 13q12-q14. Genomics 1992; 12:430-434.
66. Davis TH, Morton CC, Miller-Cassman R, Balk SP, Kadin ME: Hodgkin's disease, lymphomatoid papulosis, and cutaneous T-cell lymphoma derived from a common T-cell clone. N. Engl. J. Med. 1992; 326:1115-1122.
67. Robertson NG, Morton CC: Mapping and characterization of a novel human myc-like (MYCLK1) sequence. Genomics 1992; 13:449-451.
68. Weremowicz S, Kupsky WJ, Morton CC, Fletcher JA: Cytogenetic evidence for a chromosome 22 tumor suppressor gene in ependymoma. Cancer Genet. Cytogenet. 1992; 61:193-196.
69. Fletcher JA, Pinkus JL, Lage JM, Morton CC, Pinkus GS: Clonal 6p21 rearrangement is restricted to the mesenchymal component of an endometrial polyp. Genes Chromosomes Cancer 1992; 5:260-263.
70. Reynolds JE, Fletcher JA, Lytle CH, Nie L, Morton CC, Diehl SR: Molecular characterization of a 17q11.2 translocation in a malignant schwannoma cell line. Hum. Genet. 1992; 90:450-456.
71. Fletcher JA, Kozakewich HP, Schoenberg ML, Morton CC: Cytogenetic findings in pediatric adipose tumors: Consistent rearrangement of chromosome 8 in lipoblastoma. Genes Chromosomes Cancer 1993; 6:24-29.
72. Tanigawa G, Watkins H, Jarcho JA, Morton CC, Seidman CE, Seidman JG: Absence of major deletions or rearrangements of cardiac myosin heavy chain genes in familial hypertrophic cardiomyopathy. Circulation 1993; 87[suppl VII]:VII-11-VII-13.
73. Ney PA, Andrews NC, Jane SM, Safer B, Purucker ME, Weremowicz S, Morton CC, Goff SC, Orkin SH, Nienhuis AW: Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic-specific subunit and evidence for an associated partner. Mol. Cell. Biol. 1993; 13:5604-5612.
74. Khetarpal U, Morton CC: COL1A2 and COL2A1 expression in temporal bone of lethal osteogenesis imperfecta. Arch. Otolaryngol. Head Neck Surg. 1993; 119:1305-1314.
75. Robinson LJ, Weremowicz S, Morton CC, Michel T: Isolation and chromosomal localization of the human endothelial nitric oxide synthase (NOS3) gene. Genomics 1994; 19:350-357.
76. Smith CP, Weremowicz S, Kanai Y, Stelzner M, Morton CC, Hediger MA: Assignment of the gene coding for the human high-affinity glutamate transporter EAAC1 to 9p24: Potential role in dicarboxylic aminoaciduria and neurodegenerative disorders. Genomics 1994; 20:335-336.
77. Weremowicz S, Kozakewich HP, Haber D, Park S, Morton CC, Fletcher JA: Identification of genetically aberrant cell lineages in Wilms' tumors. Genes Chromosomes Cancer 1994; 10:40-48.
78. Mashal RD, Schoenberg Fejzo ML, Friedman AJ, Mitchner N, Nowak RA, Rein MS, Morton CC, Sklar J: Analysis of androgen receptor DNA reveals the independent clonal origins of uterine leiomyomata and the secondary nature of cytogenetic aberrations in the development of leiomyomata. Genes Chromosomes Cancer 1994; 11:1-6.
79. Khetarpal U, Robertson NG, Yoo TJ, Morton CC: Expression and localization of COL2A1 mRNA and type II collagen in human fetal cochlea. Hear. Res. 1994; 79:59-73.
80. Robertson NG, Khetarpal U, Gutiérrez-Espeleta GA, Bieber FR, Morton CC: Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening. Genomics 1994; 23:42-50.
81. Sargent MS, Weremowicz S, Rein MS, Morton CC: Translocations in 7q22 define a critical region in uterine leiomyomata. Cancer Genet. Cytogenet. 1994; 77:65-68.
82. Cole H, Weremowicz S, Morton CC, Wolf B: Localization of serum biotinidase (BTD) to human chromosome 3 in band p25. Genomics 1994; 22:662-663.
83. Newton G, Weremowicz S, Morton CC, Copeland NG, Gilbert DJ, Jenkins NA, Lawler J: Characterization of human and mouse cartilage oligomeric matrix protein. Genomics 1994; 24:435-439.
84. Magovcevic I, Weremowicz S, Morton CC, Fong S-L, Berson EL, Dryja TP: Mapping of the human cone transducin a subunit (GNAT2) gene to 1p13 and negative mutation analysis in patients with Stargardt's disease. Genomics 1995; 25:288-290.
85. Wilkins-Haug L, Roberts DJ, Morton CC: Confined placental mosaicism and intrauterine growth retardation: A case/control analysis of placentas at delivery. Am. J. Obstet. Gynecol. 1995; 172:44-50.
86. Taketo M, Parker KL, Howard TA, Tsukiyama T, Wong M, Niwa O, Morton CC, Miron PM, Seldin MF: Homologs of Drosophila Fushi-Tarazu factor 1 map to mouse chromosome 2 and human chromosome 9q33. Genomics 1995; 25:565-567.
87. Schoenberg Fejzo M, Yoon S-J, Montgomery KT, Rein MS, Weremowicz S, Krauter KS, Dorman TE, Fletcher JA, Mao J, Moir DT, Kucherlapati RS, Morton CC: Identification of a YAC spanning the translocation breakpoints in uterine leiomyomata, pulmonary chondroid hamartoma and lipoma. Physical mapping of the 12q14-15 breakpoint region in uterine leiomyomata. Genomics 1995; 26:265-271.
88. Doria A, Caldwell JS, Ji L, Reynet C, Rich SS, Weremowicz S, Morton CC, Warram JH, Kahn CR, Krolewski AS: Trinucleotide repeats at the rad locus: Allele distributions in NIDDM and mapping to a 3-cM region on chromosome 16q. Diabetes 1995; 44:243-247.
89. Gorn AH, Rudolph SM, Flannery MR, Morton CC, Weremowicz S, Wang J-T, Krane SM, Goldring SR: Expression of two human skeletal calcitonin receptor isoforms cloned from a giant cell tumor of bone: The first intracellular domain modulates ligand binding and signal transduction. J. Clin. Invest. 1995; 95:2680-2691.
90. *Ashar H, *Schoenberg Fejzo M, Tkachenko A, Zhou X, Fletcher JA, Weremowicz S, Morton CC, Chada K: Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains. Cell 1995; 82:57-65. (*co-first authors)
91. Zhao Y, Bjørbæk C, Weremowicz S, Morton CC, Moller DE: RSK3 encodes a novel pp90rsk isoform with a unique N-terminal sequence: growth factor-stimulated kinase function and nuclear translocation. Mol. Cell. Bio. 1995; 15:4353-4363.
92. Yi H, Morton CC, Weremowicz S, McBride W, Kelly K: Genomic organization and chromosomal localization of the DUSP2 gene, encoding a MAP kinase phosphatase, to human chromosome 2p11.2-q11. Genomics 1995; 28:92-96.
93. Magovcevic I, Khetarpal U, Bieber FR, Morton CC: GNAZ in human fetal cochlea: Expression, localization and potential role in inner ear function. Hear. Res. 1995; 90:55-64.
94. Magovcevic I, Berson EL, Morton CC: Detection of cone alpha transducin mRNA in human fetal cochlea and negative mutation analysis in patients with Usher syndrome. Hear. Res. 1996; 99:7-12.
95. Elson A, Kozak CA, Morton CC, Weremowicz S, Leder P: The protein tyrosine phosphatase e gene maps to mouse chromosome 7 and human chromosome 10q26. Genomics 1996; 31:373-375.
96. Basson CT, MacRae CA, Schoenberg Fejzo M, Morton CC, Spinner NB, Genin A, Krug E, Seidman JG, Seidman CE: Identification, characterization, and chromosomal localization of the human homolog (hES) of ES/130. Genomics 1996; 35:628-631.
97. Schoenberg Fejzo M, Ashar HR, Krauter KS, Powell WL, Rein MS, Weremowicz S, Yoon S-J, Kucherlapati RS, Chada K, Morton CC: Translocation breakpoints upstream of the HMGIC gene in uterine leiomyomata suggest dysregulation of this gene by a mechanism different from that in lipomas. Genes Chromosomes Cancer 1996; 17:1-6.
98. Stewart AFR, Richard III CW, Suzow J, Stephan D, Weremowicz S, Morton CC, Adra CN: Cloning of human RTEF-1, a transcriptional enhancer factor-1- related gene preferentially expressed in skeletal muscle: Evidence for an ancient multigene family. Genomics 1996; 36:68-76.
99. Schneider MC, Rodriguez AM, Nomura H, Zhou J, Morton CC, Reeders ST, Weremowicz S: A gene similar to PKD1 maps to chromosome 4q22: A candidate gene for PKD2. Genomics 1996; 38:1-4.
100. Elson A, Wang Y, Daugherty CJ, Morton CC, Zhou F, Campos-Torres J, Leder P: Pleiotrophic defects in ataxia telangiectasia protein-deficient mice. Proc. Natl. Acad. Sci. USA 1996; 93:13084-13089.
101. Rehm HL, Gutiérrez-Espeleta GA, Garcia R, Jiménez G, Khetarpal U, Priest JM, Sims KB, Keats BJB, Morton CC: Norrie gene mutation in a large Costa Rican kindred with a novel phenotype including peripheral vascular disease. Hum. Mut. 1997; 9:402-408.
102. Xing YP, Powell WL, Morton CC: The del(7q) subgroup in uterine leiomyomata: Genetic and biologic characteristics. Further evidence for the secondary nature of cytogenetic abnormalities in the pathobiology of uterine leiomyomata. Cancer Genet. Cytogenet. 1997; 98:69-74.
103. Williams AJ, Powell WL, Collins T, Morton CC: HMGI(Y) expression in human uterine leiomyomata: Involvement of another HMG architectural factor in a benign neoplasm. Am. J. Pathol. 1997; 150:911-918.
104. Gelb BD, Shi GP, Heller M, Weremowicz S, Morton C, Desnick RJ, Chapman HA. Structure and chromosomal assignment of the human cathepsin K gene. Genomics 1997; 41:258-262.
105. Quade BJ, McLachlin CM, Soto-Wright V, Zuckerman J, Mutter GL, Morton CC: Disseminated peritoneal leiomyomatosis: Clonality analysis by X chromosome inactivation and cytogenetics of a clinically benign smooth muscle proliferation. Am. J. Pathol. 1997; 150:2153-2166.
106. Robinson WP, Horsthemke B, Leonard S, Malcolm S, Morton C, Nicholls RD, Ritchie RJ, Rogan P, Schultz R, Schwartz S, Sharp J, Trent R, Wevrick R, Williamson M, Knoll JHM: Report of the third international workshop on human chromosome 15 mapping 1996. Cytogenet. Cell Genet. 1997; 76:1-13.
107. Hsu LYF, Yu M-T, Neu RL, Van Dyke DL, Benn PA, Bradshaw CL, Shaffer LG, Higgins RR, Khodr GS, Morton CC, Wang H, Brothman AR, Chadwick D, Disteche CM, Jenkins LS, Kalousek DK, Pantzar TJ, Wyatt P: Rare trisomy mosaicism diagnosed in amniocytes, involving an autosome other than chromosomes 13, 18, 20, and 21: Karyotype/phenotype correlations. Prenat. Diagn. 1997; 3:201-242.
108. Garcia-Zepeda EA, Rothenberg ME, Weremowicz S, Sarafi MN, Morton CC, Luster AD: Genomic organization, complete sequence, and chromosomal location of the gene for human eotaxin (SCYA11), an eosinophil-specific chemokine. Genomics 1997; 41:471-476.
109. Rodriguez AM, Rodin D, Nomura H, Morton CC, Weremowicz S, Schneider MC: Identification, localization and expression of two novel human genes similar to deoxyribonuclease I. Genomics 1997; 42:507-513.
110. Avraham KB, Hasson T, Sobe T, Balsara B, Testa JR, Skvorak AB, Morton CC, Copeland NG, Jenkins NA: Characterization of unconventional MYO6, the human homologue of the gene responsible for deafness in Snell's waltzer mice. Hum. Mol. Genet. 1997; 6:1225-1231.
111. Khetarpal U, Morton CC: Inner ridge cells may be the main source of tectorial membrane type II collagen: Evidence from quantitative mRNA in situ hybridization. Acta Otolaryngol. 1998; 118:177-184.
112. Skvorak AB, Robertson NG, Yin Y, Weremowicz S, Her H, Bieber FR, Beisel KW, Lynch ED, Beier DR, Morton CC: An ancient conserved gene expressed in the human inner ear: Identification, expression analysis, and chromosomal mapping of human and mouse antiquitin (ATQ1). Genomics 1997; 46:191-199.
113. Robertson NG, Skvorak AB, Yin Y, Weremowicz S, Johnson KR, Kovatch KA, Battey JF, Bieber FR, Morton CC: Mapping and characterization of a novel cochlear gene in human and in mouse: A positional candidate gene for a deafness disorder, DFNA9. Genomics 1997; 46:345-354.
114. Rein MS, Powell WL, Walters FC, Weremowicz S, Cantor RM, Barbieri RL, Morton CC: Cytogenetic abnormalities in uterine myomas are associated with myoma size. Mol. Hum. Reprod. 1998; 4:83-86.
115. Greinwald JH, Jr., Scott DA, Marietta JR, Carmi R, Manaligod J, Ramesh A, Zbar RIS, Kraft ML, Elbedour K, Yairi Y, Musy M, Skvorak AB, Van Camp G, Srikumari Srisailapathy CR, Lovett M, Morton CC, Sheffield VC, Smith RJH: Construction of a P1-derived artificial chromosome and yeast artificial chromosome contigs encompassing the DFNB7 and DFNB11 region of chromosome 9q13-21. Genome Res. 1997; 7:879-886.
116. Guo N, Weremowicz S, Lynch N, Lim B-L, Schwaeble W, Peerschke EIB, Morton CC, Reid KBM, Ghebrehiwet B, Sastry KN: Assignment of C1QBP encoding the C1q globular domain binding protein (gC1q-R) to human chromosome 17 band p13.3 by in situ hybridization. Cytogenet. Cell Genet. 1997; 77:283-284.
117. Morton CC: Sounding out a novel sulphate transporter. Nature Genet. 1997; 17:370-371.
118. Vahava O, Morell R, Lynch ED, Weiss S, Kagan ME, Ahituv N, Morrow JE, Lee MK, Skvorak AB, Morton CC, Blumenfeld A, Frydman M, Friedman TB, King M-C, Avraham KB: Mutation in transcription factor POU4F3 causes inherited progressive hearing loss in humans. Science 1998; 279:1950-1954.
119. Wang A, Liang Y, Fridell RA, Probst FJ, Wilcox ER, Touchman JW, Morton CC, Morell RJ, Noben-Trauth K, Camper SA, Friedman TB: Mutations in a novel unconventional myosin MYO15 cause human non-syndromic hereditary deafness DFNB3. Science 1998; 280:1447-1451.
120. Eudy JD, Weston MD, Yao S, Hoover DM, Rehm HL, Ma-Edmonds M, Yan D, Ahmad I, Cheng JJ, Ayuso C, Cremers C, Davenport S, Moller C, Talmadge CB, Beisel KW, Tamayo M, Morton CC, Swaroop A, Kimberling WJ, Sumegi J: Mutation of a gene encoding a protein with extracellular matrix motifs in Usher syndrome type IIa. Science 1998; 280:1753-1757.
121. Morton CC: Many tumors and many genes: Genetics of uterine leiomyomata. Am. J. Pathol. 1998; 153:1015-1020.
122. Scott DA, Greinwald, Jr. JH, Marietta JR, Drury S, Swiderski RE, Vinas A, DeAngelis MM, Carmi R, Ramesh A, Kraft ML, Elbedour K, Skvorak AB, Friedman RA, Srikumari Srisailapathy CR, Verhoeven K, Van Camp G, Lovett M, Deininger PL, Batzer MA, Morton CC, Keats BJ, Smith RJH, Sheffield VC: Identification and mutation analysis of a cochlear-expressed, zinc finger protein gene at the DFNB7/11 and dn hearing-loss-loci on human chromosome 9q and mouse chromosome 19. Gene 1998; 215:461-469.
123. Nomura H, Turco AE, Pei Y, Kalaydjieva L, Weremowicz S, Ji W, Morton C, Meisler M, Reeders ST, Zhou J: Identification of PKDL, a novel polycystic kidney disease 2-like gene whose murine homologue is deleted in mice with kidney and retinal defects. J. Biol. Chem. 1998; 273:25967-25973.
124. Adra CN, Iyengar AR, Syed FA, Kanaan IN, Rilo HLR, Yu W, Kheraj R, Lin SR, Horiuchi T, Khan S, Weremowicz S, Lim B, Morton CC, Higgs DR: Human ARHGDIG, a GDP-dissociation inhibitor for Rho proteins: Genomic structure, sequence, expression analysis, and mapping to chromosome 16p13.3. Genomics 1998; 53:104-109.
125. Pedeutour F, Quade BJ, Weremowicz S, Dal Cin P, Ali S, Morton CC: Localization and expression of the human estrogen receptor beta gene in uterine leiomyomata. Genes Chromosomes Cancer 1998; 23:361-366.
126. Quintana DG, Hou Z, Thome KC, Hou Z, Ligon AH, Morton CC, Dutta A: ORC5L, a new member of the human origin recognition complex, is deleted in uterine leiomyomas and malignant myeloid diseases. J. Biol. Chem. 1998; 273:27137-27145.
127. Weremowicz S, Morton CC: Is HMGIC rearranged due to cryptic paracentric inversion of 12q in karyotypically normal uterine leiomyomas? Genes Chromosomes Cancer 1999; 24:172-173.
128. *Robertson NG, *Lu L, Heller S, Merchant SN, Eavey RD, McKenna M, Nadol, Jr. JB, Miyamoto RT, Linthicum, Jr. FH, Neto JFL, Hudspeth AJ, Seidman CE, **Morton CC, **Seidman JG: Mutations in a novel cochlear gene cause DFNA9, a human nonsyndromic deafness with vestibular dysfunction. Nature Genet. 1998; 20:299-303. (*co-first authors, **co-last authors)
129. Guo N, Mogues T, Weremowicz S, Morton CC, Sastry KN: The human ortholog of rhesus mannose-binding protein-A gene is an expressed pseudogene that localizes to chromosome 10. Mamm. Gen. 1998; 9:246-249.
130. Gattás GJF, Quade BJ, Nowak RA, Morton CC: HMGIC expression in human adult and fetal tissues and in uterine leiomyomata. Genes Chromosomes Cancer 1999; 25:316-322.
131. Karet FE, Finberg KE, Nelson RD, Nayir A, Mocan H, Sanjad SA, Rodriguez-Soriano J, Santos F, Cremers CWRJ, Di Pietro A, Hoffbrand BI, Winiarski J, Bakkalõglu A, Özen S, Dusunsel R, Goodyer P, Hulton SA, Wu DK, Skvorak AB, Morton CC, Cunningham MJ, Jha V, Lifton RP: Mutations in the B1 subunit of H+-ATPase cause renal tubular acidosis with sensorineural deafness. Nature Genet. 1999; 21:84-90.
132. de Kok YJM, Bom SJH, Brunt TM, Kemperman MH, van Beusekom E, van der Velde-Visser S, Robertson NG, Morton CC, Huygen PLM, Verhagen WIM, Brunner HG, Cremers CWRJ, Cremers FPM: A Pro51Ser mutation in the COCH gene is associated with late-onset autosomal dominant progressive sensorineural hearing loss with vestibular defects. Hum. Mol. Genet. 1999; 8:361-366.
133. Skvorak AB, Weng Z, Yee AJ, Robertson NG, Morton CC: Human cochlear expressed sequence tags provide insight into cochlear gene expression and identify candidate genes for deafness. Hum. Mol. Genet. 1999; 8:439-452.
134. Morton CC, Christian SL, Donlon TA, Driscoll DJ, Fink JK, Gabriel JM, Gotway G, Greally JM, Hitchins MP, Howard HC, Ji Y, Leonard S, Lerner T, Magenis E, Malcolm S, Ohta T, Rainier S, Rees M, Riley B, Robinson WP, Saitoh S, Schultz R, Sell S, Sharp JD, Talbot C, Trent R, Wevrick R, Nicholls RD: Report of the fourth international workshop on human chromosome 15 mapping 1997. Cytogenet. Cell Genet. 1999; 84:11-21.
135. Robertson NG, Morton CC: Beginning of a molecular era in hearing and deafness. Clin. Genet. 1999; 55:149-159.
136. Basson CT, Huang T, Lin RC, Bachinsky DR, Weremowicz S, Vaglio A, Bruzzone R, Quadrelli R, Lerone M, Romeo G, Silengo M, Pereira A, Krieger J, Mesquita SF, Kamisago M, Morton CC, Pierpont MEM, Müller CW, Seidman JG, Seidman CE: Different TBX5 interactions in heart and limb defined by Holt-Oram syndrome mutations. Proc. Natl. Acad. Sci. USA 1999; 96:2919-2924.
137. Ing PS, Van Dyke DL, Caudill SP, Reidy JA, Bice G, Bieber FR, Buchanan PD, Carroll AJ, Cheung SW, DeWald G, Donahue RP, Gardner HA, Higgins J, Hsu LYF, Jamehdor M, Keitges EA, Laundon CH, Luthardt FW, Mascarello J, May KM, Meck JM, Morton C, Patil S, Peakman D, Pettenati MJ, Rao N, Sanger WG, Saxe DF, Schwartz S, Sekhon GS, Vance GH, Wyandt HE, Yu CW, Zenger-Hain J, Chen ATL: Detection of mosaicism in amniotic fluid cultures: A CYTO2000 collaborative study. Genet. Med. 1999; 1:94-97.
138. Fransen E, Verstreken M, Verhagen WIM, Wuyts FL, Huygen PLM, D'Haese P, Robertson NG, Morton CC, McGuirt WT, Smith RJH, Declau F, Van de Heyning PH, Van Camp G: High prevalence of symptoms of Menière's disease in three families with a mutation in the COCH gene. Hum. Mol. Genet. 1999; 8:1425-1429.
139. Sornberger K, Weremowicz S, Williams AJ, Quade BJ, Ligon AH, Pedeutour F, Vanni R, Morton CC: Expression of HMGIY in three uterine leiomyomata with complex rearrangements of chromosome 6. Cancer Genet. Cytogenet. 1999; 114:9-16.
140. Dal Cin P, Quade BJ, Weremowicz S, Morton CC, Pauwels P, Van Den Berghe H: Primary parauterine leiomyoma with a t(6;14). Genes Chromosomes Cancer 1999; 26:383-384.
141. Skvorak Giersch AB, Morton CC: Genetic causes of nonsyndromic hearing loss. Curr. Opin. Pediatr. 1999; 11:551-557.
142. Pedeutour F, Ligon AH, Morton CC: Génétique des léiomyomes utérins. Bull. Cancer 1999; 86:920-928.
143. Veale M, Raab M, Li Z, da Silva AJ, Kraeft S-K, Weremowicz S, Morton CC, Rudd CE: Novel isoform of lymphoid adaptor FTN-T-binding protein (FYB-130) interacts with SLP-76 and up-regulates interleukin 2 production. J. Biol. Chem. 1999; 274:28427-28435.
144. Rehm HL, Morton CC: A new era in the genetics of hearing. Genet. Med. 1999; 1:295-302.
145. Tsukaguchi H, Weremowicz S, Morton CC, Hediger MA: Functional and molecular characterization of the human neutral solute channel aquaporin-9. Am. J. Physiol. 1999; 277:F685-696.
146. Dangond F, Foerznler D, Weremowicz S, Morton, CC, Beier DR. Gullans SR: Cloning and expression of a murine histone deacetylase (mHdac3) cDNA and mapping to a region of conserved synteny between murine chromosome 18 and human chromosome 5. Mol. Cell. Biol. Res. Commun. 1999; 2:91-96.
147. Faisal Ahmed S, Marsh DJ, Weremowicz S, Morton CC, Williams DM, Eng C: Balanced translocation of 10q and 13q, including the PTEN gene, in a boy with a human chorionic gonadotropin-secreting tumor and the Bannayan-Riley-Ruvalcaba syndrome. J Clin Endocrinol Metab 1999; 84:4665-4670.
148. Newton G, Weremowicz S, Morton CC, Jenkins NA, Gilbert DJ, Copeland NG, Lawler J: The thrombospondin-4 gene. Mamm. Gen. 1999; 10:1010-1016.
149. Pedeutour F, Quade BJ, Sornberger K, Tallini G, Ligon AH, Weremowicz S, Morton CC: Dysregulation of HMGIC in a uterine lipoleiomyoma with a complex rearrangement including chromosomes 7, 12, and 14. Genes Chromosomes Cancer 2000; 27:209-215.
150. Vaughan CJ, Weremowicz S, Goldstein MM, Casey M, Hart M, Hahn RT, Devereux RB, Girardi L, Schoen FJ, Fletcher JA, Morton CC, Basson CT: A t(2;19)(p13;p13.2) in a giant invasive cardiac lipoma from a patient with multiple lipomatosis. Genes Chromosomes Cancer 2000; 28:133-137.
151. Ligon AL, Morton CC: Genetics of uterine leiomyomata. Genes Chromosomes Cancer 2000; 28:235-245.
152. Wang Y, Mackenzie B, Tsukaguchi H, Weremowicz S, Morton CC, Hediger MA: Human vitamin C (L-ascorbic acid) transporter SVCT1. Biochem. Biophys. Res. Comm. 2000; 267:488-494.
153. Gattás GJF, Pedeutour F, Ligon AH, Morton CC: Genética do leiomioma de útero. Rev. Bras. Clin. Terap. 2000; 26:27-34.
154. Guo L, Schreiber TH, Weremowicz S, Morton CC, Lee C, Zhou J: Identification and characterization of a novel polycystin family member, polycystin-L2, in mouse and human: Sequence, expression, alternative splicing, and chromosomal localization. Genomics 2000; 64:241-251.
155. Robertson NG, Heller S, Lin JS, Resendes BL, Weremowicz S, Denis CS, Bell AM, Hudspeth AJ, Morton CC: A novel conserved cochlear gene, OTOR: Identification, expression analysis and chromosomal mapping. Genomics 2000; 66:242-248.
156. Casey M, Vaughan CJ, He J, Hatcher CJ, Winter JM, Weremowicz S, Montgomery K, Kucherlapati R, Morton CC, Basson CT: Mutations in the protein kinase A R1 regulatory subunit cause familial cardiac myxomas and Carney complex. J. Clin. Invest. 2000; 106:R31-38.
157. Ahituv N, Taggart RT, Sobe T, Robertson NG, Morton CC, Avraham KB: Genomic structure of the human unconventional myosin VI gene. Gene 2000; 261:269-275.
158. Peng JB, Chen XZ, Berger UV, Weremowicz S, Morton CC, Vassilev PM, Brown EM, Hediger MA: Human calcium transport protein CaT1. Biochem. Biophys. Res. Comm. 2000; 278:326-332.
159. Adra CN, Donato JL, Badovinac R, Syed F, Kheraj R, Cai H, Moran C, Kolker MT, Turner H, Weremowicz S, Shirakawa T, Morton CC, Schnipper LE, Drews R: SMARCAD1, a novel human helicase family-defining member associated with genetic instability: cloning, expression, and mapping to 4q22-q23, a band rich in breakpoints and deletion mutants involved in several human diseases. Genomics 2000; 69:162-173.
160. Dal Cin P, Atkins L, Ford C, Ariyanayagam S, Armstrong SA, George R, Cleary A, Morton CC: Multiple copies of AML1 in childhood acute lymphoblastic leukemias. Genes Chromosomes Cancer 2001; 30:407-409.
161. Lee C, Fowler DJ, Lemyre E, Sandstrom MMcH, Holmes LB, Morton CC: Prenatal diagnosis and molecular cytogenetics in a case of partial proximal trisomy 14 and monosomy 21. Am. J. Med. Genet. 2001; 100:246-250.
162. Weremowicz S, Sandstrom DJ, Morton CC, Niedzwiecki CA, Sandstrom MMcH, Bieber FR: FISH for rapid detection of aneuploidy: Experience in 911 prenatal cases. Prenat. Diagn. 2001; 21:262-269.
163. Qin X, Miwa T, Aktas H, Gao M, Lee C, Qian Y-M, Morton CC, Shahsafaei A, Song W-C, Halperin JA: Genomic structure, functional comparison, and tissue distribution of mouse Cd59a and Cd59b. Mamm. Gen. 2001; 12:582-589.
164. Wayne S, Robertson NG, DeClau F, Chen N, Verhoeven K, Prasad S, Tranebjärg L, Morton CC, Ryan AF, Van Camp G, Smith RJH: Mutations in the transcriptional activator EYA4 cause late-onset deafness at the DFNA10 locus. Hum. Mol. Genet. 2001; 10:195-200.
165. Cheung VG, Nowak N, Jang W, Kirsch IR, Zhao S, Chen X-N, Furey TS, Kim U-J, Kuo W-L, Olivier M, Conroy J, Kasprzyk A, Massa H, Yonescu R, Sait S, Thoreen C, Snijders A, Lemyre E, Bailey JA, Bruzel A, Burrill WD, Clegg SM, Collins S, Dhami P, Friedman C, Han CS, Herrick S, Lee J, Ligon AH, Lowry S, Morley M, Narasimhan S, Osoegawa K, Peng Z, Plajzer-Frick I, Quade BJ, Scott D, Sirotkin K, Thorpe AA, Gray JW, Hudson J, Pinkel D, Ried T, Rowen L, Shen-Ong GL, Strausberg RL, Birney E, Callen DF, Cheng J-F, Cox DR, Doggett NA, Carter NP, Eichler EE, Haussler D, Korenberg JR, Morton CC, Albertson D, Schuler G, de Jong P, Trask BJ: Integration of cytogenetic landmarks into the draft sequence of the human genome. Nature 2001; 409:953-958.
166. Lee C, Gisselsson D, Jin C, Nordgren A, Ferguson DO, Blennow E, Fletcher JA, Morton CC: Limitations of chromosome classification by multicolor karyotyping. Am. J. Hum. Genet. 2001; 68:1043-1047.
167. Lee C, Murray MF, Miron PM, Marsden D, Irons M, Wilkins-Haug LE, Morton CC: Clinical picture: Multicolor karyotyping. Lancet 2001; 357:1240.
168. Caldwell GM, Eddy RL, Day CD, Haley LH, Cooper PR, Sait SSJ, Hejtmancik F, Smith RJH, Morton CC, Higgins MJ, Shows TB: Mapping of genes and transcribed sequences in a gene rich 400-kb region on human chromosome 11p15.1->p14. Cytogenet. Cell Genet. 2001; 92:103-107.
169. Nucci MR, Weremowicz S, Tallini G, Sornberger K, Morton CC, Quade BJ: Chromosomal translocation t(8;12) induces aberrant HMGIC expression in aggressive angiomyxoma of the vulva. Genes Chromosomes Cancer 2001; 32:172-176.
170. Alagramam KN, Yuan H, Kuehn MH, Murcia CL, Wayne S, Srikumari Srisailpathy CR, Lowry RB, Knaus R, Van Laer L, Bernier FP, Schwartz S, Lee C, Morton CC, Mullins RF, Ramesh A, Van Camp G, Hageman GS, Woychik RP, Smith RJH: Mutations in the novel protocadherin PCDH15 cause Usher syndrome type 1F. Hum. Mol. Genet. 2001; 10:1709-1718.
171. Robertson NG, Resendes BL, Lin JS, Lee C, Aster JC, Adams JC, Morton CC: Inner ear localization of mRNA and protein products of COCH, mutated in the sensorineural deafness and vestibular disorder, DFNA9. Hum. Mol. Genet, 2001; 10:2493-2500.
172. Davids MS, Crawford E, Weremowicz S, Morton CC, Copeland NG, Gilbert DJ, Jenkins NA, Phelan MC, Comb MJ, Melnick MB: STK25 is a candidate gene for pseudopseudohypoparathyroidism. Genomics 2001; 77:2-4.
173. Resendes BL, Williamson RE, Morton CC: At the speed of sound: gene discovery in the auditory system. Am. J. Hum. Genet. 2001; 69:923-935.
174. Sharpless NE, Ferguson DO, O’Hagan RC, Castrillon DH, Lee C, Farazi PA, Alson S, Fleming J, Morton CC, Frank K, Chin L, Alt FW, DePinho RA: Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions. Mol. Cell 2001; 8:1187-1196.
175. Quade BJ, Dal Cin P, Neskey DM, Weremowicz S, Morton CC: Intravenous leiomyomatosis: Molecular and cytogenetic analysis of a case. Modern Pathol. 2002; 15:351-356.
176. Yuasa T, Bhuvarahamurthy V, Weremowicz S, Morton CC, Guo L, Zhou J: The sequence, expression, and chromosomal localization of a novel polycystic kidney disease 1-like gene, PKD1L1, in human. Genomics 2002; 79:376-386.
177. Resendes BL, Robertson NG, Szustakowski JD, Resendes RJ, Weng Z, Morton CC: Gene discovery in the auditory system: Characterization of additional cochlear expressed sequences. J. Assoc. Res. Otolaryngol. 2002; 3:45-54.
178. Ligon AH, Scott IC, Takahara K, Greenspan DS, Morton CC: PCOLCE deletion and expression analyses in uterine leiomyomata. Cancer Genet. Cytogenet. 2002; 137:133-137.
179. Rehm HL, Zhang D-S, Brown MC, Burgess B, Halpin C, Berger W, Morton CC, Corey DP, Chen Z-Y: Vascular defects and sensorineural deafness in a mouse model of Norrie disease. J. Neurosci. 2002; 22:4286-4292.
180. Picker JD, Fan Y-S, Fowler DJ, Weremowicz S, Cox GF, Morton CC, Lee C: Multicolor karyotypic interpretation of a heterochromatin-associated marker chromosome in a dysmorphic girl with developmental delay. Am. J. Med. Genet. 2002; 110:393-396.
181. Dal Cin P, Morton CC: 1q42-q44 is rarely involved cytogenetically in sporadic uterine leiomyomata. Cancer Genet. Cytogenet. 2002; 138:92-93.
182. Zhu C, Mills KD, Ferguson DO, Lee C, Manis J, Fleming J, Gao Y, Morton CC, Alt FW: Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations. Cell 2002; 109:811-821.
183. Stover EH, Borthwick KJ, Bavalia C, Eady N, Fritz DM, Rungroj N, Giersch ABS, Morton CC, Axon PR, Akil I, Al-Sabban EA, Baguley DM, Bianca S, Bakkaloglu A, Bircan Z, Chauveau D, Clermont M-J, Guala A, Hulton SA, Kroes H, Li Volti G, Mir S, Mocan H, Nayir A, Ozen S, Rodriguez Soriano J, Sanjad SA, Tasic V, Taylor CM, Topaloglu R, Smith AN, Karet FE: Novel ATP6V1B1 and ATP6V0A4 mutations in autosomal recessive distal renal tubular acidosis, with new evidence for hearing loss. J. Med. Genet. 2002; 39:796-803.
184. Enerback C, Porter DA, Seth P, Sgroi D, Gaudet J, Weremowicz S, Morton CC, Schnitt S, Pitts RL, Stampl J, Barnhart K, Polyak K: Psoriasin expression in mammary epithelial cells in vitro and in vivo. Cancer Res 2002; 62:43-47.
185. Dal Cin P, Quade BJ, Neskey DM, Kleinman MS, Weremowicz S, Morton CC: Intravenous leiomyomatosis is characterized by a der(14)t(12;14)(q15;q24). Genes Chromosomes Cancer 2003; 36:205-206.
186. Quade BJ, Weremowicz S, Neskey DM, Vanni R, Ladd C, Dal Cin P, Morton CC: Fusion transcripts involving HMGA2 are not a common molecular mechanism in uterine leiomyomata with rearrangements in 12q15. Cancer Res. 2003; 63:1351-1358.
187. Iannaccone A, Breuer DK, Wang X, Kuo SF, Normando EM, Filipova E, Baldi A, Hiriyanna S, MacDonald CB, Baldi F, Cosgrove D, Morton CC, Swaroop A, Jablonski MM: Clinical and immunohistochemical evidence for an X-linked retinitis pigmentosa syndrome with recurrent infections and hearing loss in association with an RPGR mutation. J. Med. Genet. 2003; 40:e118.
188. Mason HR, NowakRA, MortonCC, Castellot, Jr. JJ. Heparin inhibits the motility and proliferation of human myometrial and leiomyoma smooth muscle cells. Am. J. Pathol. 2003; 162:1895-1904.
189. Gross KL, NeskeyDM, ManchandaN, WeremowiczS, KleinmanMS, Nowak RA, Ligon AH, RogallaP, DrechslerK, BullerdiekJ, Morton CC. HMGA2 expression in uterine leiomyomata and myometrium: Quantitative analysis and tissue culture studies. Genes Chromosomes Cancer 2003; 38:68-79.
190. Robertson NG, Hamaker SA, Patriub V, Aster JC, Morton CC: Subcellular localization, secretion, and post-translational processing of normal cochlin, and of mutants causing the sensorineural deafness and vestibular disorder, DFNA9. J. Med. Genet. 2003: 40:479-486.
191. Scherer SW, Cheung J, MacDonald JR, Osbourne LR, Nakabayashi K, Herbrick J-A, Carson AR, Parker-Katiraee, Skaug J, Khaja R, Zhang J, Hudek AK, Li M, Haddad M, Duggan GE, Fernandez BA, Kanematsu E, Gentles S, Christopoulos CC, Choufani S, Kwasnicka D, Zheng XH, Nusskern D, Zhang Q, Gu Z, Lu F, Zeesman S, Teshima I, Chitayat D, Shuman C, Weksberg R, Zackai EH, Grebe TA, Cox SR, Kirkpatrick SJ, Rahman N, Friedman JM, Heng HHQ, Pelicci PG, Lococo F, Belloni E, Shaffer LG, Pober B, Morton CC, Gusella JF, Bruns GAP, Korf BR, Quade BJ, Ligon AH, Ferguson H, Higgins AW, Leach NT, Herrick SR, Lemyre E, Farra CG, Kim H-G, Summers AM, Gripp KW, Roberts W, Szatmari P, Winsor EJT, Grzeschik K-H, Teebi A, Minassian BA, Kere J, Armengol L, Pugana MA, Estivill X, Wilson MD, Koop BF, Tosi S, Moore GE, Boright AP, Zlotorynski E, Kerem B, Kroisel PM, Petek E, Oscier DG, Mould SJ, Döhner H, Döhner K, Rommens JM, Vincent JB, Venter JC, Li PW, Mural RJ, Adams MD, Tsui L-C: Human chromosome 7: DNA sequence and biology. Science 2003, 300:767-772.
192. Porter D, Weremowicz S, Chin K, Seth P, Keshaviah A, Lahti-Domenici J, Bae YK, Monitto CL, Merlos-Suarez A, Chan J, Hulette CM, Richardson A, Morton CC, Marks J, Duyao M, Hruban R, Gabrielson E, Gelman R, Polyak K: A neural survival factor is a candidate oncogene in breast cancer. Proc. Natl. Acad. Sci. USA 2003; 100:10931-10936.
193. Dettori T, Frau DV, Garcia JL, Pierantoni G, Lee C, Hernandez JM, Fusco A, Morton CC, Vanni R: Comprehensive conventional and molecular cytogenetic characterization of B-CPAP, a human papillary thyroid carcinoma-derived cell line. Cancer Genet. Cytogenet. 2004; 151:171-177.
194. Resendes BL, Kuo SF, Robertson NG, Giersch ABS, Honrubia D, Ohara O, Adams JC, Morton CC: Isolation from cochlea of a novel human intronless gene with predominant fetal expression. J. Assoc. Res. Otolaryngol. 2004; 5:185-202.
195. Cowan CA, Klimanskaya I, McMahon, Atienza J, Witmyer J, Zucker JP, Wang S, Morton CC, McMahon AP, Powers D, Melton DA: Derivation of embryonic stem cell lines from human blastocysts. N. Engl. J. Med. 2004; 350:1353-1356.
196. Quade BJ, Tao-Yeuan Wang T-Y, Sornberger K, Dal Cin P, Mutter GL, Morton CC: Molecular pathogenesis of uterine smooth muscle tumors from transcriptional profiling. Genes Chromosomes Cancer 2004; 40:97-108.
197. Roberts AE, Irons MB, Kimonis VE, Mulliken JB, Morton CC, Lee C, Listewnik M: Description of a case of distal 2p trisomy by array-based comparative genomic hybridization: a high resolution genome-wide investigation for chromosomal aneuploidy in a single assay. Am. J. Med. Genet. 2004; 130:204-207.
198. Iannaccone A, Wang X, Jablonski MM, Kuo SF, Baldi A, Cosgrove D, Morton CC, Swaroop A: Increasing evidence for syndromic phenotypes associated with RPGR mutations. Am. J. Ophthalmol. 2004; 137:785-786.
199. Gross KL, Panhuysen CIM, Kleinman MS, Goldhammer H, Jones ES, Nassery N, Stewart EA, Morton CC: Involvement of fumarate hydratase in nonsyndromic uterine leiomyomata: Genetic linkage analysis and FISH studies. Genes Chromosomes Cancer 2004; 41:183-190.
200. Veugelers M, Bressan M, McDermott DA, Weremowicz S, Morton CC, Mabry CC, Lefaivre J-F, Zunamon A, Destree A, Chaudron J-M, Basson CT: Mutation of perinatal myosin heavy chain associated with a Carney complex variant. N. Engl. J. Med. 2004, 351:460-469.
201. Moore SDP, Herrick SR, Ince TA, Kleinman MS, Dal Cin P, Morton CC, Quade BJ: Uterine leiomyomata with t(10;17) disrupt the histone acetyltransferase MORF. Cancer Res. 2004; 64:5570-5577.
202. Hida K, Hida Y, Amin DN, Flint AF, Panigrahy D, Morton CC, Klagsbrun M: Tumor-associated endothelial cells with cytogenetic abnormalities. Cancer Res.2004; 64:8249-8255.
203. Bhattacharya SK, Rockwood EJ, Smith S, Bonilha V, Crabb JS, Peachey N, Kuchtey R, Robertson NG, Morton CC, Crabb JW: Proteomics reveals cochlin deposits in glaucomatous trabecular meshwork. J. Biol. Chem. 2005; 280:6080-6084.
204. *Ligon AH, *Moore SDP, Parisi MA, Mealiffe ME, Harris DJ, Ferguson HL, Quade BJ, Morton CC: Constitutional rearrangement of the architectural factor HMGA2: A novel human phenotype including overgrowth and lipomas. Am. J. Hum. Genet. 2005; 76:340-348. (*co-first authors)
205. Kim H-G, Herrick SR, Lemyre E, Kishikawa S, Salisz JA, Seminara S, MacDonald ME, Bruns GAP, Morton CC, Quade BJ, Gusella JF: Hypogonadotropic hypogonadism and cleft lip and palate due to a balanced translocation producing haploinsufficiency for FGFR1. J. Med. Genet. 2005; 42:666-672.
206. Makishima T, Rodriguez CI, Robertson NG, Morton CC, Stewart CL, Griffith AJ: Targeted disruption of mouse Coch provides functional evidence that DFNA9 hearing loss is not a COCH haploinsufficiency disorder. Hum. Genet. 2005; 118:29-34.
207. Street VA, Kallman, JC, Robertson NG, Kuo SF, Morton CC, Phillips JO: A novel DFNA9 mutation in the vWFA2 domain of COCH alters a conserved cysteine residue and intrachain disulfide bond formation resulting in progressive hearing loss and site-specific vestibular and central oculomotor dysfunction. Am. J. Med. Genet. 2005; 139:86-95.
208. Morton CC, Nance WE: Newborn hearing screening: A silent revolution. N. Engl. J. Med. 2006; 354:2151-2164.
209. Moore SDP, Offor O, Ferry JA, Amrein PC, Morton CC, Dal Cin P: ELF4 is fused to ERG in a case of acute myeloid leukemia with a t(X;21)(q25-26;q22). Leuk. Res. 2006; 30:1037-1042.
210. *Christacos NC, *Quade BJ, +Dal Cin P, +Morton CC: Uterine leiomyomata with deletions of 1p represent a distinct cytogenetic subgroup associated with unusual histologic features. Genes Chromosomes Cancer 2006; 45:304-312. (*co-first authors, +co-last authors)
211. Kemperman MH, De Leenheer EMR, Huygen PLM, van Duijnhoven G, Morton CC, Robertson NG, Cremers FPM, Kremer H, Cremers CWRJ: Audiometric, vestibular, and genetic aspects of a DFNA9 family with a G88E COCH mutation. Otol. Neurotol. 2005; 26:926-933.
212. Treon SP, Hunter ZR, Aggarwal A, Ewen EP, Masota S, Lee C, Santos DD, Hatjiharissi E, Xu L, Leleu X, Tournilhac O, Patterson CJ, Manning R, Branagan AR, Morton CC: Characterization of familial Waldenstrom's macroglobulinemia. Ann. Onc. 2006; 17:488-494.
213. Stewart EA, Morton CC: The genetics of uterine leiomyomas: What clinicians need to know. Obstet. Gynecol. 2006; 107:917-921.
214. Robertson NG, Cremers CWRJ, Huygen PLM, Ikezono T, Krastins B, Kremer H, Kuo SF, Liberman MC, Merchant SN, Miller CE, Nadol, Jr. JB, Sarracino DA, Verhagen WI, Morton CC: Cochlin immunostaining of inner ear pathologic deposits and proteomic analysis in DFNA9 deafness and vestibular dysfunction. Hum. Mol. Genet. 2006; 15:1071-1085.
215. Wilkins-Haug L, Quade B, Morton CC: Confined placental mosaicism as a risk factor among newborns with fetal growth restriction. Prenat. Diagn. 2006; 26:428-432.
216. Weremowicz S, Sandstrom DJ, Morton CC, Miron PM: Validation of DNA probes for preimplantation genetic diagnosis (PGD) by fluorescence in situ hybridization (FISH). Prenat. Diagn. 2006; 26:1042-1050.
217. Sivakumaran TA, Resendes BL, Robertson NG, Giersch ABS, Morton CC: Characterization of an abundant COL9A1 transcript in the cochlea with a novel 3’ UTR: expression studies and detection of miRNA target sequence. J. Assoc. Res. Otolaryngol. 2006; 7:160-172.
218. Baek M-J, Park H-M, Johnson JM, Altuntas CZ, Jaini R, Thomas DM, Ball EJ, Robertson NG, Morton CC, Hughes GB, Tuohy VK: Increased frequencies of cochlin specific T cells in patients with autoimmune sensorineural hearing loss. J. Immunol. 2006; 177:4203-4210.
219. Alkuraya FS, Saadi I, Lund JJ, Turbe-Doan A, Morton CC, Maas RL: SUMO1 haploinsufficiency leads to cleft lip and palate. Science 2006; 313:1751.
220. Kim H-G, Higgins AW, Herrick SR, Kishikawa S, Nicholson L, Kutsche K, Ligon AH, Harris DJ, MacDonald ME, Bruns GAP, Morton CC, Quade BJ, Gusella JF: Candidate loci for Zimmermann-Laband syndrome at 3p14.3. Am. J. Med. Genet. A 2007; 143A:107-111.
221. Lu W, van Eerde AM, Fan X, Quintero-Rivera F, Kulkarni S, Ferguson H, Kim H-G, Fan Y, Xi Q, Li Q, Sanlaville D, Andrews W, Sundaresan V, Bi W, Yan J, Giltay JC, Wijmenga C, de Jong TPVM, Feather SA, Woolf AS, Rao Y, Lupski JR, Eccles MR, Quade BJ, Gusella JF, Morton CC, Maas RL: Disruption of ROBO2 is associated with urinary tract anomalies and confers risk of vesicoureteral reflux. Am. J. Hum. Genet. 2007; 80:616-632.
222. Leach NT, Sun Y, Michaud S, Zheng Y, Ligon KL, Ligon AH, Sander T, Korf BR, Lu W, Harris DJ, Gusella JF, Maas RL, Quade BJ, Cole AJ, Kelz MB, Morton CC: Disruption of diacylglycerol kinase delta(DGKD)associated with seizures in humans and mice. Am. J. Hum. Genet. 2007; 80:792-799.
223. Williamson RE, Darrow KN, Michaud S, Jacobs JS, Jones MC, Eberl DF, Maas RL, Liberman MC, Morton CC: Methylthioadenosine phosphorylase (MTAP) in hearing: Gene disruption by chromosomal rearrangement in a hearing impaired individual and model organism analysis. Am. J. Med. Genet. A 2007; 143A:1630-1639.
224. Hodge JC, Morton CC: Genetic heterogeneity among uterine leiomyomata: Insights into malignant progression. Hum. Mol. Genet. 2007; 16:R7-R13.
225. Quintero-Rivera F, Leach NT, de la Chapelle A, Gusella JF, Morton CC, Harris DJ: Is the disruption of an N-myristoyltransferase (NMT2) associated with hypoplastic testes? Am. J. Med. Genet. A 2007; 143:1796-1798.
226. Lu W, Quintero-Rivera F, Fan Y, Alkuraya F, Donovan DJ, Xi Q, Turbe-Doan A, Li Q-G, Campbell CG, Shanske AL, Sherr EH, Ahmad A, Peters R, Rilliet B, Parvex P, Bassuk AG, Harris DJ, Ferguson H, Kelly C, Walsh CA, Gronostajski RM, Devriendt K, Higgins A, Ligon AH, Quade BJ, Morton CC, Gusella JF, Maas RL: NFIA haploinsufficiency is associated with a CNS malformation syndrome and urinary tract defects. PLoS Genet. 2007; 3:830-843.
227. Gabashvili IS, Sokolowski B, Morton CC, Giersch ABS: Ion channel gene expression in the inner ear. J. Assoc. Res. Otolaryngol. 2007; 8:305-328.
228. Chanock S, Manolio T, Boehnke M, Boerwinkle E, Hunter D, Thomas G, Abecasis G, Altshuler D, Bailey-Wilson JE, Brooks LD, Cardon LR, Daly M, Donnelly P, Fraumeni , Jr. JF, Freimer NB, Gerhard DS, Gunter C, Guttmacher AE, Guyer MS, Harris EL, Hirschhorn J, Hoh J, Hoover R, Kong CA, Merikangas KR, Morton CC, Palmer LJ, Phimister EG, Rice JP, Roberts J, Rotimi C, Tucker MA, Vogan K, Wacholder S, Wijsman EM, Winn DM, Collins FS: What constitutes replication of a genotype-phenotype sssociation? Summary of an NCI-NHGRI Working Group. Nature 2007; 447:655-660.
229. Picciani R, Desai K, Guduric-Fuchs J, Cogliati T, Morton CC, Bhattacharya SK: Cochlin in the eye: functional implications. Prog. Retin. Eye Res. 2007; 26:453-469.
230. Huyck KL, Panhuysen CIM, T.Cuenco K, Zhang J, Goldhammer H, Jones ES, Somasundaram P, Lynch AM, Harlow BL, Lee H, Stewart EA, Morton CC: The impact of race as a risk factor for symptom severity and age at diagnosis of uterine leiomyomata among affected sisters. Amer. J. Obstet. Gynecol. 2008; 168.e1-168.e9.
231. Kim H-G, Kishikawa S, Higgins AW, Seong I-S, Donovan DJ, Shen Y, Lally E, Weiss LA, Najm J, Kutsche K, Descartes M, Holt L, Braddock S, Troxell R, Kaplan L, Volkmar F, Klin A, Tsatsanis K, Harris DJ, Noens I, Pauls DL, Daly MJ, MacDonald ME, Morton CC, Quade BJ, Gusella JF: Disruption of neurexin 1 associated with autism spectrum disorder. Am. J. Hum. Genet. 2008; 82:199-207.
232. Williamson RE, Darrow KN, Giersch ABS, Resendes BL, Liberman MC, Tasheva ES, Morton CC: Expression studies of osteoglycin/mimecan (OGN) in the cochlea and auditory phenotype of Ogn-deficient mice. Hear. Res. 2008; 237:57-65.
233. Higgins AW, Alkuraya FS, Bosco AF, Brown KK, Bruns GAP, Donovan DJ, Eisenman R, Fan Y, Farra CG, Ferguson HL, Gusella JF, Harris DJ, Herrick SR, Kelly C, Kim H-G, Kishikawa S, Korf BR, Kulkarni S, Lally E, Leach NT, Lemyre E, Lewis J, Ligon AH, Lu W, Maas RL, MacDonald ME, Moore SDP, Peters RE, Quade BJ, Quintero-Rivera F, Saadi I, Shen Y, Shendure J, Williamson RE, Morton CC: Characterization of apparently balanced chromosomal rearrangements from the Developmental Genome Anatomy Project. Am. J. Hum. Genet. 2008; 82:712-722.
234. Hodge JC, Quade BJ, Rubin MA, Stewart EA, Dal Cin P, Morton CC: Molecular and cytogenetic characterization of plexiform leiomyomata provide further evidence for genetic heterogeneity underlying uterine fibroids. Am. J. Pathol. 2008; 172:1403-1410.
235. Lee C, Morton CC: Structural genomic variation and personalized medicine. N. Engl. J. Med. 2008; 358:740-741.
236. Poitras J, Dal Cin P, Aster JC, DeAngelo DJ, Morton CC: Novel SSBP2-JAK2 fusion gene resulting from a t(5;9)(q14.1;p24.1) in pre-B acute lymphocytic leukemia. Genes Chromosomes Cancer 2008; 47:884-889.
237. Robertson NG, Jones SM, Sivakumaran TA, Giersch ABS, Jurado SA, Call LM, Miller CE, Maison SF, Liberman MC, Morton CC: A targeted Coch missense mutation: a knock-in mouse model for DFNA9 late-onset hearing loss and vestibular dysfunction. Hum. Mol. Genet. 2008; 17:3426-3434.
238. Hodge JC, T.Cuenco K, Huyck KL, Somasundaram P, Panhuysen CIM, Stewart EA, Morton CC: Uterine leiomyomata and decreased height: A common HMGA2 predisposition allele. Hum. Genet., 2009, 125:257-263.
239. Brown KK, Alkuraya FS, Matos M, Robertson RL, Kimonis VE, Morton CC: NR2F1 deletion in a patient with a de novo paracentric inversion, inv(5)(q15q33.2), and syndromic deafness. Am. J. Med. Genet. 2009; 149A:931-938.
240. Hodge JC, Park PJ, Dreyfuss JM, Assil-Kishawi I, Somasundaram P, Semere LG, Stewart EA, Quade BJ, Lynch AM, Morton CC: Identifying the molecular signature of del(7)(q22q32) uterine leiomyomata using a paired analysis. Genes Chromosomes Cancer 2009, in press.
241. Brown KK, Reiss JA, Crow K, Ferguson HL, Kelly C, Fritzch B, Morton CC: Deletion of an enhancer near DLX5 and DLX6 in a family with hearing loss, craniofacial defects, and an inv(7)(q21.3q35). Hum. Genet. 2009, in press.
242. Kuo SF, Whitney C, Malicki J, Morton CC: Functional characterization of KCTD12. Mech. Dev., under revision.
Books and Other Monographs:
Editor:
1. Donlon TA, Morton CC. Report of the committee on the genetic constitution of chromosome 15. In: Cuticchia AJ, Pearson PL, editors. Human Gene Mapping 1993: A Compendium. Baltimore: The Johns Hopkins University Press, 1994:493-505.
2. 2. Dracopoli NC, Haines JL, Korf BR, Moir DT, Morton CC, Seidman CE, Seidman JG, Smith DR, editors. Current Protocols in Human Genetics. New York: Greene Publishing Associates/Wiley-Interscience, 1994.
3. Donlon TA, Morton CC. Report of the committee on the genetic constitution of chromosome 15. In: Cuticchia AJ, editor. Human Gene Mapping 1994: A Compendium. Baltimore: The Johns Hopkins University Press, 1995:582-598.
4. Donlon TA, Morton CC. Report of the committee on the genetic constitution of chromosome 15. In: Cuticchia AJ, editor. Human Gene Mapping 1995: A Compendium. Baltimore: The Johns Hopkins University Press, 1996:862-886.
Book Chapters:
1. Holt J, Morton CC, Nienhuis AW, Leder P. Molecular mechanisms of hematological neoplasms. In: Stamatoyannopoulos G, Nienhuis AW, Leder P, Majerus PW, editors. Molecular Basis of Blood Diseases. Philadelphia: W.B. Saunders; 1987. pp. 347‑76.
2. Morton CC. Cytogenetics for the hematologist. In: Handin RI, Lux SE, Stossel TP, editors. Blood: Principles and Practice of Hematology. Philadelphia: J.B. Lippincott; 1995. pp. 93-124.
3. Morton CC, Miron P. Cytogenetics in reproduction. In: Yen SSC, Jaffe RB, Barbieri, R.L. editors. Reproductive Endocrinology. Fourth Edition. Philadelphia: W.B. Saunders; 1999, pp. 323-344.
4. Giersch ABS, Morton CC: Cytogenetics and cochlear ESTs for identification of genes involved in hearing and deafness. In: Keats BJB, Popper AN, Fay RR, editors. Genetics and Auditory Disorders, Springer Handbook of Auditory Research. Springer-Verlag, New York, Inc., 2001, pp. 92-120.
5. Gross KL, Morton CC. Uterine Leiomyoma, Cellular and Genetic Characteristics. In: Schwab M, editor. Encyclopedic Reference of Cancer. Berlin: Springer, 2001, pp 945-948.
6. Dal Cin P, Morton CC. Cytogenetics for the hematologist. In: Handin RI, Lux SE, Stossel TP, editors. Blood: Principles and Practice of Hematology. Philadelphia: J.B. Lippincott; 2003, pp. 95-122.
7. Giersch ABS, Morton CC: Genetic hearing loss associated with chromosome disorders. In: Toriello HV, Reardon W, Gorlin RJ, editors: Hereditary Hearing Loss and its Syndromes. New York: Oxford University Press, 2004, pp. 462-476.
8. Morton CC, Miron P. Cytogenetics in reproduction. In: Strauss, J.F., Barbieri, R.L. editors. Yen and Jaffe’s Reproductive Endocrinology. Fifth Edition. Philadelphia: W.B. Saunders; 2004, pp.813-837.
9. Robertson NR, Morton CC. COCH. In: Willems PJ, editor. Genetic Hearing Loss. New York: Marcel Dekker, Inc., 2004, pp. 329-349.
10. Dal Cin P, Morton CC. Cytogenetic and other genetic insights into the pathogenesis of uterine leiomyomata. In: Brosens I, editor. Uterine Leiomyomata: Pathogenesis and Management. Chapter 2: Cytogenetic and other genetic insights into the pathogenesis of uterine leiomyomata. Milton Park, Oxon: Taylor and Francis, 2005, pp. 11-23.
11. Hodge JC, Morton CC. Uterine leiomyomata: Aspects in reproduction, susceptibility, and tumor cytogenetics. In: Wells D, editor. Cytogenetics in Reproductive Medicine. Landes Bioscience http://eurekah.com/abstract.php?chapid=2932&bookid=184&catid=70.
12. Huyck KL, Morton CC. Uterine Leiomyoma, Cellular and Genetic Characteristics. In: Schwab M, editor. Encyclopedic Reference of Cancer. Berlin: Springer, 2007.
Conference Proceedings:
1. Morton CC, Brown JA, Nance WE, Woods DE, Kirsch IR, Evans GA, Korman AJ, Strominger JL. Gene localization and chromosome rearrangement studied by in situ hybridization with DNA clones derived from human histocompatibility antigen genes. In: Sasazuki T, Tada T, editors. Immunogenetics: Its Application to Clinical Medicine. Proceedings of the Fifth International Congress of Immunology, Tokyo, 1983. Tokyo: Academic Press, 1984:239-251.
2. Kirsch IR, Brown JA, Laurence J, Korsmeyer SJ, Morton CC, Hollis GF. Regions of cell specific transcriptional activity are targets for chromosomal translocation. In: Bishop JM, Rowley JD, Greaves M, editors. Genes and Cancer. Proceedings of the Cetus/UCLA Symposia on Molecular and Cellular Biology. New York: Alan R. Liss, Inc., 1984:583-587.
3. Morton CC, Gross KL, Powell WL, Sornberger K, Quade BJ. HMGIC and HMGIY rearrangements as secondary events in the genesis of uterine leiomyomas: Evidence for the genetic basis of fibroids. Proceedings of the First International Workshop on the Role of High Mobility Group Proteins in Human Disorders, Bremen, 1998. Berlin: Springer-Verlag, in press.
4. Morton CC. Genetic approaches to the study of uterine leiomyomata. In: Advances in Uterine Leiomyoma Research. Environ. Health Perspect. 2000; 108 (suppl 5):775-778.
5. Morton CC: Gene discovery in the auditory system using a tissue specific approach. Ann. Otol. Rhin. Laryn., in press.
6. Morton CC: Gene discovery in the auditory system using a tissue specific approach. Am. J. Med. Genet., 2004; 130A:26-28. Proceedings of the 34th annual March of Dimes Clinical Genetics Conference, San Diego, CA, 2003.
Monograph in a Series:
1. Ligon AH, Morton CC. Genetics of uterine leiomyomata. In: Sciarra JJ, editor. Gynecology and Obstetrics. Philadelphia: Lippincott Williams & Wilkins, 1999, Chapter 96, pp. 1-11.
2. Lee C, Morton CC. Advances in the genetics of hearing and deafness. In: Orloff L, editor. CONTACT. Washington: Cochlear Implant Club International, Inc., 1999; 13:35-38.
3. Ligon AH, Morton CC. Leiomyomata: Heritability and cytogenetic studies. Oxford Press: Human Reproduction Update Symposium, 2001; 7:1-7.
4. Gross KL, Morton CC. Genetics and the development of fibroids. Clin. Obstet. Gynecol. 2001; 44:335-349.
5. Lee C, Lemyre E, Miron PM, Morton CC. Multicolor fluorescence in situ hybridization in clinical cytogenetic diagnostics. Curr. Opin. Pediatr.2001; 13:550-555.
6. Gross KL, Morton CC. The genetics of fibroids: cytogenetics and inheritance. Infert. Reprod. Med. Clin. N. Am. 2002; 13:283-302.
7. Nassery N, Gross KL, Morton CC: Leiomyomata. Fert. Steril., in press.
8. Call LM, Morton CC: Continuing to break the sound barrier: genes in hearing. Curr. Opin. Genet. Dev. 2002; 12:343-348.
9. Morton CC: Genetics, genomics and gene discovery in the auditory system. Hum. Mol. Genet. 2002; 11:1229-1240.
10. Farra C, Morton CC: Chromosome 15. In: Encyclopedia of the Human Genome. Nature Publishing Group. http://ehg.naturereference.com/.
11. Christacos NC, Ligon AH, Morton CC. Genetics of uterine leiomyomas. In: Sciarra JJ, editor. Gynecology and Obstetrics. Philadelphia: Lippincott Williams & Wilkins, 2004.
12. Lobel MK, Somasundaram P, Morton CC: The genetic heterogeneity of uterine leiomyomata. In: Arici A, editor: Obstet. Gynecol. Clin. N. Am. 2006; 33:13-39.
13. Farra C, Morton CC: Chromosome 15. In: Encyclopedia of Life Sciences. John Wiley & Sons, Ltd: Chichester http://www.els.net/ [DOI: 10.1002/9780470015902.a0005824.pub2], 2007.
14. Lynch AM, Morton CC: Fumarate hydratase. In: Atlas of Genetics and Cytogenetics in Oncology and Haematology. http://atlasgeneticsoncology.org/Genes/FHID40573ch1q42.html, 2007.
15. Lynch AM, Morton CC: Uterine leiomyomata. In: Atlas of Genetics and Cytogenetics in Oncology and Haematology. http://atlasgeneticsoncology.org/Tumors/leiomyomID5031.html, 2007.
Book Reviews:
1. Morton CC: The Chromosomes and Their Disorders: An Introduction for Clinicians. Fourth edition. By G.H. Valentine. 223 pp., illustrated. London, William Heinemann Medical Books, 1986. N. Engl. J. Med. 1987; 316:1350.
Letters:
1. Iannaccone A, Wang XF, Kuo SF, Baldi A, Cosgrove D, Morton CC, Swaroop A, Jablonski MM: X-linked pseudo-Usher syndrome due to mutations in the RPGR gene: A newly recognized clinical entity. [e-publication] J. Med. Genet. 2003 http://jmg.bmjjournals.com/cgi/eletters/40/8/609#29.
Patents
1. Robertson N, Morton C, Van Camp G, Fransen E, Van de Heyning P, inventors; The Brigham & Women’s Hospital and University of Antwerp assignees. Methods of diagnosis and treatment of meniere disease. US patent 6,730,475. 2006 May 4.
2. Morton CC, Robertson N, inventors; The Brigham & Women’s Hospital assignee. Compositions to detect lesions associated with hearing loss in the cochlear gene, COCH5B2. US patent 7,030,235. 2006 Apr 18.
Abstracts:
1. Casson CR, Brown JA: Observations on NORs, QM heteromorphisms and satellite associations in twins: An MZ twin pair with a 14;21 translocation. Va. J. Sci. 1979; 29(2). Presented at the Annual Meeting of the Virginia Academy of Science, Richmond, VA, May 8-11, 1979.
2. Casamassima AC, Casson CR, Kelley TE, Kodroff MB, Landenburger G, Nance WE, Wolf B: Spondylothoracic dysplasia with anal and urogenital anomalies in a Mennonite sibship. Presented at the 1979 Birth Defects Conference, Chicago, IL, June 24-27, 1979.
3. Casson CR, Corey LA, Nance WE, Winter PM, Brown JA: Usefulness of nucleolar organizer regions (NOR) in twin zygosity determination. Am. J. Hum. Genet. 1979; 31:90A. Presented at the 30th Annual Meeting of the American Society of Human Genetics, Minneapolis, MN, October 3-6, 1979.
4. Bieber FR, Nance WE, Brown JA, Casson CR, Jordan RL, Mohanakumar T, Redwine FO: Genetic evidence of polar body twinning in man. Am. J. Hum. Genet. 1979; 31:118A. Presented at the 30th Annual Meeting of the American Society of Human Genetics, Minneapolis, MN, October 3-6, 1979.
5. Cantor RM, Casson CR, Chiu CY, Golden WL, Corey LA, Nance WE: A genetic analysis of taste threshold for PTC. Proceedings of the 3rd International Congress on Twin Studies 1980; 3:52. Presented at the 3rd International Congress on Twin Studies, Jerusalem, Israel, June 16-20, 1980.
6. Casson CR, Corey LA, Nance WE, Brown JA: Quinacrine mustard (QM) and nucleolar organizer region (NOR) heteromorphisms in twins. Proceedings of the 3rd International Congress on Twin Studies 1980; 3:31. Presented at the 3rd International Congress on Twin Studies, Jerusalem, Israel, June 16-20, 1980.
7. Phelan MC, Morton CC, Swenson BA, Winter PM, Nance WE: Evidence for Lyonization of G6PD in a monozygotic twin pair. Am. J. Hum. Genet. 1980; 32:123A. Presented at the 31st Annual Meeting of the American Society of Human Genetics, New York, NY, September 24-27, 1980.
8. Morton CC, Bieber FR, Mohanakumar T, Nance WE, Redwine FO, Brown JA: Codominant expression of major histocompatibility complex (MHC) in a case of partial trisomy 6p resulting from an insertion and inversion involving heterologous chromosomes. Am. J. Hum. Genet. 1980; 32:81A. Presented at the 31st Annual Meeting of the American Society of Human Genetics, New York, NY, September 24-27, 1980.
9. Morton CC, Mohanakumar T, Nance WE, Brown JA: Trisomic codominant expression of the major histocompatibility complex (MHC) due to meiotic recombination. Abstracts of the 6th International Congress of Human Genetics 1981; 119. Presented at the 6th International Congress of Human Genetics, Jerusalem, Israel, September 13-17, 1981.
10. Morton CC, Brown JA, Holmes WM, Wolf B: Stain intensity of the nucleolus organizer region (NOR) reflects incorporation of uridine into mature ribosomal RNA (rRNA). Am. J. Hum. Genet. 1981; 33:112A. Presented at the 32nd Annual Meeting of the American Society of Human Genetics, Dallas, TX, October 28-31, 1981.
11. Morton CC, Brown JA, Nance WE, Schmickel RD, Holmes WM: Analysis of human BamH1 ribosomal DNA (rDNA) restriction heteromorphisms in twins. Am. J. Hum. Genet. 1982; 34:165A. Presented at the 33rd Annual Meeting of the American Society of Human Genetics, Detroit, MI, September 29-October 2, 1982.
12. Morton CC, Brown JA, Evans GA, Nance WE, Mohanakumar T, Kirsch IR: Detection and localization of an extra HLA locus in a karyotypically normal male by chromosomal in situ hybridization. Am. J. Hum. Genet. 1982; 34:136A. Presented at the 33rd Annual Meeting of the American Society of Human Genetics, Detroit, MI, September 29-October 2, 1982.
13. Morton CC, Kirsch IR, Taub RA, Orkin SH, Brown JA: Localization of the beta‑globin gene by chromosomal in situ hybridization in a normal male and an individual with erythroleukemia. Cytogenet. Cell Genet. 1984; 37:544. Presented at the 7th International Workshop on Human Gene Mapping, Los Angeles, CA, August 21-26, 1983.
14. Dryja T, Rapaport JM, Albert DM, Morton CC, Gusella JF, Bruns G: Restriction fragment length polymorphisms from 13q. Cytogenet. Cell Genet. 1984; 37:457. Presented at the 7th International Workshop on Human Gene Mapping, Los Angeles, CA, August 21-26, 1983.
15. Michelson AM, Bruns GAP, Morton CC, Orkin SH: Characterization of the human phosphoglycerate kinase multigene family. Am. J. Hum. Genet. 1983; 35:180A. Presented at the 34th Annual Meeting of the American Society of Human Genetics, Norfolk, VA, October 30-November 2, 1983.
16. Morton CC, Neve RL, Bruns GAP, Ma NSF, Cox D, Klinger HP, Kurnit DM: Recent evolution of non-ribosomal DNA sequence homology in the pericentromeric regions of human acrocentric chromosomes. Am. J. Hum. Genet. 1983; 35:145A. Presented at the 34th Annual Meeting of the American Society of Human Genetics, Norfolk, VA, October 30-November 2, 1983.
17. Kurnit DM, Wright TC, Morton CC, Schwaber J, Orkin R, Destrempes M, Aldridge J, Van Praagh R, Matthysse S: Down syndrome: Increased adhesiveness of fetal lung and endocardial cushion fibroblasts in vitro. Am. J. Hum. Genet. 1983; 35:102A. Presented at the 34th Annual Meeting of the American Society of Human Genetics, Norfolk, VA, October 30-November 2, 1983.
18. Kirsch IR, Brown J, Morton C, Korsmeyer S, Hollis G: Translocations that highlight chromosomal regions of differentiated activity. J. Cell Biochem. Suppl. 1984; 8A:88. Presented at the Cetus/UCLA Symposia on Molecular and Cellular Biology, Steamboat Springs, CO, February 11-17, 1984.
19. Chung JH, Siebenlist U, Morton CC, Leder P: Mapping and characterization of a transposed human immunoglobulin D gene segment. Fed. Proc. 1984; 43:1486.
20. Morton CC, Duby AD, Eddy RL, Murre C, Waldmann RA, Shows TB, Seidman JG: The human T‑cell receptor beta chain and the T‑cell gamma gene are assigned to chromosome 7. Cytogenet. Cell Genet. 1985; 40:703. Presented at the 8th International Workshop on Human Gene Mapping, Helsinki, Finland, August 4-10, 1985.
21. Morton C, Bell G, Shows T: Epidermal growth factor (EGF) is located at q25‑27 on human chromosome 4. Cytogenet. Cell Genet. 1985; 40:702. Presented at the 8th International Workshop on Human Gene Mapping, Helsinki, Finland, August 4-10, 1985.
22. Morton C, Rall L, Bell G, Shows T: Human insulin‑like growth factor‑1 (IGF1) is encoded at 12q22‑24.1, and insulin‑like growth factor‑2 (IGF2) is at 11p15. Cytogenet. Cell Genet. 1985; 40:703. Presented at the 8th International Workshop on Human Gene Mapping, Helsinki, Finland, August 4-10, 1985.
23. Duby AD, Morton CC, Murre C, Klein KA, Quertermous T, Waldmann RA, Eddy RL, Shows TB, Bongiovanni KF, Waldmann TA, Seidman JG: Arrangement and rearrangement of human T-cell receptor beta and gamma chain genes. Presented at the meeting on T‑Cell Receptors, Given Institute of Pathobiology, Aspen, CO, July 5-7, 1985.
24. Amos J, Morton C, Phelan M, Watkins P, Tanzi R, Schweig E, Miller W, Gusella J: Molecular approaches to chromosome 21 abnormalities. Am. J. Hum. Genet. 1985; 37:85A. Accepted for presentation at the 36th Annual Meeting of the American Society of Human Genetics, Salt Lake City, UT, October 9-12, 1985.
25. Klickstein LB, Wong WW, Smith JA, Morton C, Fearon DT, Weis JH: Identification of long homologous repeats in human CR1. Presented at the XIth International Complement Workshop, Miami, FL, November 3-5, 1985.
26. Harris P, Morton CC, Gugliemi P, Li F, Kelly K, Leder P, Latt SA: Mapping by chromosome sorting of gene probes, including c-myc, to the derivative chromosomes of 3;8 translocation with familial renal cancer. Presented at Analytical Cytometry XI, Hilton Head, SC, November 17-22, 1985.
27. Morton CC, Nussenzweig MC, Pettengill OS, Shows TB, Sorenson GD, Leder P: Isolation and characterization of myc-related sequences. Submitted to the International Conference on Hormones, Growth Factors and Oncogenes in Pulmonary Carcinoma, Dartmouth-Hitchcock Medical Center, Hanover, NH, August 30-September 2, 1987.
28. Morton CC, Bonthron DT, Collins T: Platelet‑derived growth factor A chain is assigned to 7p22-p21. Cytogenet. Cell Genet. 1987; 46:664. Presented at the 9th International Meeting on Human Gene Mapping, Paris, France, September 6-11, 1987.
29. Beier DR, Morton CC, Leder A, Leder P: A transgene maps very close to the microcytic anemia locus on mouse chromosome 15. Am. J. Hum. Genet. 1987; 41:A207. Presented at the 38th Annual Meeting of the American Society of Human Genetics, San Diego, CA, October 7-10, 1987.
30. Sandstrom MMcH, Stryker JM, Frigoletto FD, Morton CC: Early amniocentesis for chromosome analysis: a preliminary experience. Am. J. Hum. Genet. 1987; 41:A285.
31. Kadin ME, Sako D, Morton C, Newcom SR, Su IJ: Characterization of a neoplastic T-cell line from a patient with cutaneous T-cell lymphoma and regressing T-cell skin lesions. Laboratory Investigation, in press. Accepted for presentation to the 1988 meeting of the International Academy of Pathology.
32. Fletcher JA, Morton CC: Basal cell nevus syndrome: cytogenetic evidence for a genetic origin in common with familial adenomatous polyposis. Am. J. Hum. Genet. 1988; 43:A23. Presented at the 39th Annual Meeting of the American Society of Human Genetics, New Orleans, LA, October 12-15, 1988.
33. Petersen E, Wyler B, Morton C, Clevers H, Bruns G, Handin RI: The gene encoding GpIb-alpha is intron-depleted and is only expressed in cells of megakaryocytic lineage. Presented at the 30th Annual Meeting of the American Society of Hematology, San Antonio, TX, December 3-6, 1988.
34. Fletcher JA, Lipinski KK, Corson JM, Morton CC: Cytogenetics of peripheral nerve sheath tumors. Cancer Genet. Cytogenet. 1989; 41:224A. Presented at the 3rd International Workshop on Chromosomes in Solid Tumors, Tuscon, AZ, February 26-28, 1989.
35. Morton CC, Eddy RL, Shows TB, Clark PRH, Sabina RL, Holmes EW: Human AMP deaminase-1 gene (AMPD1) is mapped to chromosome 1. Presented at the 10th International Workshop on Human Gene Mapping, New Haven, CT, June 4-10, 1989.
36. Weremowicz S, Fox EA, Morton CC: Assignment of the human angiogenin gene to chromosome 14q11‑q13. Presented at the 10th International Workshop on Human Gene Mapping, New Haven, CT, June 4‑10, 1989.
37. Krauss CM, Richkind K, Robertson NG, Morton CC: Use of anonymous DNA sequences previously mapped to 17p to confirm a deletion of 17p13. Presented at the 21st Annual March of Dimes Clinical Genetics Conference, Boston, MA, July 9-12, 1989.
38. Fletcher JA, Pinkus GS, Morton CC: Combined immunohistochemical/cytogenetic (IH/C) approach reveals lineage specificity of chromosomal aberrations: application to solid tumors. Am. J. Hum. Genet. 1989; 45:A21. Presented at the 40th Annual Meeting of the American Society of Human Genetics, Baltimore, MD, November 11-15, 1989.
39. McAfee MW, Arnos KS, Toomey KE, Morton CC: t(2;13) in a deaf individual: implications for mapping genes involved in hearing. Am. J. Hum. Genet. 1989; 45:A82. Presented at the 40th Annual Meeting of the American Society of Human Genetics, Baltimore, MD, November 11‑15, 1989.
40. Fletcher JA, Morton CC, Pavelka K, Weidner N, Pinkus GS, Tepper RI, Lage J, Kozakewich HP, Corson JM: Chromosome aberrations in virtually all soft tissue sarcomas (STS): diagnostic role of cytogenetic analyses. Presented at the 1990 meeting of the International Academy of Pathology, Boston, MA, March 1990.
41. Fletcher JA, Pinkus GS, Weidner N, Morton CC: Lineage‑restricted chromosome aberrations in benign breast tumors. Presented at the 1990 meeting of the International Academy of Pathology, Boston, MA, March 1990.
42. Fletcher JA, Lipinski KK, Kozakewich HP, Morton CC: Consistent rearrangement of chromosome 8 in lipoblastoma. Presented at the 1990 meeting of the International Academy of Pathology, Boston, MA, March 1990.
43. Fletcher J, Morton C, Pavelka K, Weidner N, Pinkus G, Tepper R, Lage J, Kozakewich H, Corson J: Diagnostic relevance of chromosome rearrangements and genetic instability in malignant soft tissue tumors (STT). Presented at the annual meeting of the American Society for Clinical Oncology, Washington, D.C., May 20-22, 1990.
44. Kadin ME, Su IJ, Cavaille-Coll M, Morton CC, Fletcher JA, Newcom SR, Said J: Ki-1+ lymphoma cell lines in cutaneous T-cell lymphoma. Submitted for presentation at the 4th International Conference on Malignant Lymphoma: Current Status and Prospects, Lugano, Switzerland, June 6-9, 1990.
45. Rein MS, Fletcher JA, Pavelka K, Morton CC, Friedman AJ: Cytogenetic abnormalities associated with uterine leiomyomata. Submitted for presentation at the 46th annual meeting of the American Fertility Society, October 13-18, 1990.
46. Fletcher JA, Morton CC: Diagnostic relevance of cytogenetic aberrations in malignant soft tissue tumors (STT). Am. J. Hum. Genet. 1990; 47:A7. Submitted for presentation at the 41st annual meeting of the American Society of Human Genetics, Cincinnati, OH, October 16-20, 1990.
47. Robertson NG, Pomponio RJ, Mutter GL, Morton CC: MYCL2: An intronless X-linked gene expressed in adult testis. Am. J. Hum. Genet. 1990; 47:A116. Presented at the 41st annual meeting of the American Society of Human Genetics, Cincinnati, OH, October 16-20, 1990.
48. Kadin ME, Cavaille-Coll MW, Sioutos N, Fletcher JA, Morton CC, Pastuszak W, Rezuke W, Altman AJ: Childhood Ki-1+ anaplastic large cell lymphoma: Establishment and characterization of a new tumor cell line transplantable to SCID mice. Presented at the 32nd annual meeting of the American Society of Hematology, Boston, MA, November 28-December 4, 1990.
49. Kadin ME, Cavaille-Coll MW, Morton CC: Tumor progression in Ki-1+ cutaneous T-cell lymphomas is related to escape from inhibition by transforming growth factor-beta. Presented at the 32nd annual meeting of the American Society of Hematology, Boston, MA, November 28-December 4, 1990.
50. Fletcher J, Cibas E, Granados R, Joste N, Donovan K, Morton C, Corson J: Consistent chromosome aberrations and genetic stability in malignant mesotheliomas (MM): Diagnostic relevance. Presented at the 1991 meeting of the International Academy of Pathology, Chicago, IL, March 1991.
51. Fletcher J, Morton C, Corson J, Kozakewich H: Genetic instability in malignant soft tissue tumors (MSTT). Presented at the 1991 meeting of the International Academy of Pathology, Chicago, IL, March 1991.
52. Joste NE, Morton CC, Corson JM, Fletcher JA: Cytogenetic complexity and genetic instability in non-small cell lung cancers. Presented at the Fourth International Workshop on Chromosomes in Solid Tumors, Tuscon, AZ, February 24-26, 1991.
53. Fletcher JA, Corson JM, Kozakewich HP, Morton CC: Genetic instability (GI): biologic relevance in 185 bone and soft tissue (B&ST) tumors. Presented at the Fourth International Workshop on Chromosomes in Solid Tumors, Tuscon, AZ, February 24-26, 1991.
54. Morton CC, Robertson NG: Isolation and characterization of a novel myc-like (MYCLK1) sequence. Presented at the 11th International Workshop on Human Gene Mapping, London, England, August 18-22, 1991.
55. White JJ, Ledbetter DH, Eddy RL, Shows TB, Stewart DA, Nuell MJ, Friedman V, Wood CM, Owens GA, McClung JK, Danner DB, Morton CC: Assignment of the human prohibitin gene (PHB) to chromosome 17q21. Presented at the 11th International Workshop on Human Gene Mapping, London, England, August 18-22, 1991.
56. Magovcevic I, Bieber FR, Morton CC: Characterization of G proteins in human cochlea. Am. J. Hum. Genet. (Supplement) 1991; 49:413. Presented at the 8th International Congress of Human Genetics, Washington, DC, October 6-11, 1991.
57. Morton CC, McAfee MW, Robertson NG, Bieber FR: Cloning genes involved in hearing from auditory tissues. Am. J. Hum. Genet. (Supplement) 1991; 49:6. Presented at the 8th International Congress of Human Genetics, Washington, DC, October 6-11, 1991.
58. Robertson NG, Morton CC: Isolation and physical mapping of a novel myc‑related sequence. Am. J. Hum. Genet. (Supplement) 1991; 49:387. Presented at the 8th International Congress of Human Genetics, Washington, DC, October 6-11, 1991.
59. Schoenberg ML, Coyle H, Rein MS, Fletcher JA, Morton CC: Molecular cytogenetic characterization of a chromosome aberration in a uterine leiomyoma: application of FISH and PCR techniques. Am. J. Hum. Genet. (Supplement) 1991; 49:249. Presented at the 8th International Congress of Human Genetics, Washington, DC, October 6-11, 1991.
60. Weremowicz S, Kupsky W, Morton CC, Fletcher JA: Evidence for a chromosome 22 tumor suppressor gene in ependymoma. Am. J. Hum. Genet. (Supplement) 1991; 49:253. Presented at the 8th International Congress of Human Genetics, Washington, DC, October 6-11, 1991.
61. Wilkins‑Haug L, Neish AS, Aggarwal A, Roberts DJ, Morton CC: Placental mosaicism in intrauterine growth retardation: confirmation of cytogenetic findings by Fluorescence In Situ Hybridization (FISH). Am. J. Hum. Genet. (Supplement) 1991; 49:178. Presented at the 8th International Congress of Human Genetics, Washington, DC, October 6-11, 1991.
62. Klein KA, Fletcher JA, Morton CC, Corey LA, Ren S, Yu RK, DeVries GH: Characterization of a cell line derived from a malignant schwannoma in a patient with neurofibromatosis type I. Am. J. Hum. Genet. (Supplement) 1991; 49:395. Presented at the 8th International Congress of Human Genetics, Washington, DC, October 6-11, 1991.
63. Wood CM, White JJ, Stewart DA, Nuell MJ, Ledbetter DH, Eddy, Jr. RL, Shows TB, Morton CC, Danner DB: A novel intracellular antiproliferative protein, prohibitin, is the mammalian equivalent of the D. melanogaster gene product, Cc, essential for development. Am. J. Hum. Genet. (Supplement) 1991; 49:423. Presented at the 8th International Congress of Human Genetics, Washington, DC, October 6-11, 1991.
64. Morton CC, Weremowicz S, Schoenberg ML, Fletcher JA: Applications of fluorescence in situ hybridization (FISH) to problems in solid tumor cytogenetics. Presented at the International Symposium on Molecular Cytogenetics, Lake Tahoe, CA, February 5-8, 1992.
65. Sanak M, M'Rad R, Deschenes G, Zhou J, Morton CC, Robertson NG, Heuertz S, Bonaiti-Pellié C, Holvoet-Vermaut L, Antignac C, Gubler M-C, Broyer M, Grunfeld J-P, Tryggvason K, Hors-Cayla M-C: Alport syndrome: Genetic study of 31 families. Submitted for presentation at the 3rd X Chromosome Workshop, Amalfi, Italy, April 3-4, 1992.
66. Morton CC, Bieber FR, Gutiérrez-Espeleta GA, Khetarpal U, Robertson NG: Cloning genes involved in hearing from a human fetal cochlear cDNA library. Presented at The Molecular Biology of Hearing and Deafness, University of California, San Diego, School of Medicine, San Diego, CA, May 1-4, 1992.
67. Khetarpal U, Robertson NG, Bieber FR, Morton CC: Expression of COL1A2 and COL2A1 in second trimester human fetal cochlea. Am. J. Hum. Genet. (Supplement) 1992; 51:A130. Presented at the 42nd Annual Meeting of the American Society of Human Genetics, San Francisco, CA, November 9-13, 1992.
68. Schoenberg ML, Morton CC: Microdissection cloning of 12q14-q15, a chromosomal region consistently rearranged in uterine leiomyomata. Am. J. Hum. Genet. (Supplement) 1992; 51:A117. Presented at the 42nd Annual Meeting of the American Society of Human Genetics, San Francisco, CA, November 9-13, 1992.
69. Magovcevic I, Bieber FR, Morton CC: In search of an auditory-specific G protein. Am. J. Hum. Genet. (Supplement) 1992; 51:A132. Presented at the 42nd Annual Meeting of the American Society of Human Genetics, San Francisco, CA, November 9-13, 1992.
70. Wilkins-Haug L, Roberts DJ, Morton CC: Confined placental mosaicism and intrauterine growth retardation: an analysis of 12 cases and 24 matched controls. Am. J. Hum. Genet. (Supplement) 1992; 51:A11. Presented at the 42nd Annual Meeting of the American Society of Human Genetics, San Francisco, CA, November 9-13, 1992.
71. Weremowicz S, Kozakewich HP, Morton CC, Fletcher JA: Genetic relationship of Wilms' tumor cell populations. Am. J. Hum. Genet. (Supplement) 1992; 51:A322. Published in the proceedings of the 42nd Annual Meeting of the American Society of Human Genetics, San Francisco, CA, November 9-13, 1992.
72. Hediger MA, Stelzner M, Smith CP, Morton CC, Lee LR, Kanai Y: Cloning, characterization and chromosomal localization of the human high affinity glutamate transporter EAAC1. Submitted for presentation at the annual meeting of the Society for Neuroscience, Washington, D.C., November 7-12, 1993.
73. Robertson NG, Bieber FR, Morton CC: Isolation of genes involved in hearing from a human fetal cochlear cDNA library using subtractive hybridization and differential screening. Am. J. Hum. Genet. (Supplement) 1993; 53:A652. Presented at the 43rd Annual Meeting of the American Society of Human Genetics, New Orleans, LA, October 5-9, 1993.
74. Sargent MS, Schoenberg ML, Weremowicz, S, Rein MS, Morton CC: Translocations in 7q indicate critical region for one uterine leiomyoma gene. Am. J. Hum. Genet. (Supplement) 1993; 53:358. Presented at the 43rd Annual Meeting of the American Society of Human Genetics, New Orleans, LA, October 5-9, 1993.
75. Weremowicz S, Kozakewich HP, Haber D, Park S, Morton CC, Fletcher JA: Identification of genetically aberrant cell lineages in Wilms tumors. Am. J. Hum. Genet. (Supplement) 1993; 53:387. Presented at the 43rd Annual Meeting of the American Society of Human Genetics, New Orleans, LA, October 5-9, 1993.
76. Magovcevic I, Bieber FR, Morton CC: Expression of GNAZ in second trimester human fetal cochlea. Am. J. Hum. Genet. (Supplement) 1993; 53:645. Presented at the 43rd Annual Meeting of the American Society of Human Genetics, New Orleans, LA, October 5-9, 1993.
77. Schoenberg ML, Sargent MS, Weremowicz S, Rein MS, Morton CC: Molecular cytogenetic characterization of a chromosome aberration in a uterine leiomyoma: mapping of cosmids with respect to the 12q14-q15 breakpoint. Am. J. Hum. Genet. (Supplement) 1993; 53:361. Presented at the 43rd Annual Meeting of the American Society of Human Genetics, New Orleans, LA, October 5-9, 1993.
78. Weremowicz S, Andrews NC, Orkin SH, Morton CC: Mapping the p45 subunit of human NFE2 to 12q13. Presented at the Human Genome Mapping Workshop 93, Kobe, Japan, November 14-17, 1993.
79. Robertson NG, Khetarpal U, Gutiérrez-Espeleta GA, Bieber FR, Morton CC: Isolation of genes involved in hearing from a human fetal cochlear cDNA library using subtractive hybridization and differential screening. Presented at The Third Biennial Mammalian Developmental Genetics Workshop, The Jackson Laboratory, Bar Harbor, ME, September 8-12, 1993.
80. Magovcevic I, Bieber FR, Morton CC: Characterization of G proteins in second trimester human fetal cochlea. Presented at The Third Biennial Mammalian Developmental Genetics Workshop, The Jackson Laboratory, Bar Harbor, ME, September 8-12, 1993.
81. Mashal RD, Rein MS, Friedman AJ, Mitchner N, Nowak RA, Schoenberg ML, Morton CC, Sklar J: Monoclonal proliferation precedes cytogenetic rearrangements in the pathogenesis of uterine leiomyomata. Presented at the Society for Gynecologic Investigation, March 1994.
82. Quade BJ, Sargent MS, Soto-Wright V, Mutter GL, Morton CC: Disseminated peritoneal leiomyomatosis: Molecular and cytogenetic evidence for a pathogenetic mechanism in common with uterine leiomyomata. Lab. Invest. 1994; 70:143a. Presented at the annual meeting of the United States and Canadian Academy of Pathology, San Francisco, CA, March 12-18, 1994.
83. Zhu J, Reynet C, Caldwell JS, Morton CC, Kahn CR: Characterization of Rad, a new diabetes-related gene expressed in muscle of type II diabetic humans. Submitted for presentation at the American Diabetes Association.
84. Frosch MP, Weremowicz S, Morton CC, Collins T: A novel cadherin-like molecule from endothelial cells. Submitted for presentation at the XIIth International Congress of Neuropathology, Toronto, Canada, September 18-23, 1994.
85. Morton CC, Schoenberg Fejzo ML, Friedman AJ, Mashal RD, Quade BJ, Rein MS, Sklar J, Walters FC, Weremowicz S, Xing YP: Molecular and cytogenetic studies of uterine leiomyomata. Presented at the NICHD Workshop, Alternatives to Hysterectomy: Bench to Bedside, Bethesda, MD, May 23-24, 1994.
86. Schoenberg Fejzo ML, Montgomery KT, Yoon S-J, Krauter KS, Kucherlapati R, Morton CC: Characterization of the t(12;14) breakpoint region in uterine leiomyomata. Presented at the Second International Workshop on Chromosome 12, New Haven, CT, June 20-22, 1994.
87. Gorn AH, Rudolph SM, Flannery MR, Morton CC, Weremowicz S, Wang J-T, Krane SM, Goldring SR: Cloning, characterization and in situ localization of the two human calcitonin receptor (CTR) isoforms from giant cell tumor of bone (GCT) and chromosomal localization of the human CTR gene. Presented at the Sixteenth Annual Meeting of the American Society for Bone and Mineral Research, Kansas City, MO, September 9-13, 1994.
88. Xing YP, Scherer SW, Tsui L-C, Morton CC: Identification of YACs flanking the 7q breakpoint region in uterine leiomyomata. Presented at the Chromosome 7 Workshop '94, Toronto, Ontario, Canada, October 14-17, 1994.
89. Robertson NG, Weremowicz S, Johnson KR, Kovatch KA, Morton CC: Mapping of the first preferentially expressed cDNA in human fetal cochlea to human 14q11.2-12 and to a region of homologous synteny on mouse chromosome 12. Am. J. Hum. Genet. (Supplement) 1994; 55:A268. Presented at the 44th Annual Meeting of the American Society of Human Genetics, Montreal, Quebec, Canada, October 18-22, 1994.
90. Schoenberg Fejzo ML, Montgomery KT, Yoon S-J, Krauter KS, Dorman T, Mao J, Moir DT, Kucherlapati R, Morton CC: Physical mapping of the t(12;14) region in uterine leiomyomata: identification of a YAC spanning the translocation breakpoint. Am. J. Hum. Genet. (Supplement) 1994; 55:A269. Presented at the 44th Annual Meeting of the American Society of Human Genetics, Montreal, Quebec, Canada, October 18-22, 1994.
91. Kovatch KA, Robertson NG, Brody TH, Morton CC: Cloning and characterization of the mouse homolog (D12H14S564E) of a novel human cochlear gene (D14S564E). Am. J. Hum. Genet. (Supplement) 1994; 55:A134. Presented at the 44th Annual Meeting of the American Society of Human Genetics, Montreal, Quebec, Canada, October 18-22, 1994.
92. Weremowicz S, Sandstrom MMcH, Walsh KA, Piecewicz AT, Morton CC: FISH of uncultured amniocytes for prenatal diagnosis: Experience in 24 cases using commercially available probes. Am. J. Hum. Genet. (Supplement) 1994; 55:A289. Presented at the 44th Annual Meeting of the American Society of Human Genetics, Montreal, Quebec, Canada, October 18-22, 1994.
93. Magovcevic I, Weremowicz S, Morton CC, Fong S-L, Berson EL, Dryja TP: Mapping of the human cone transducin a subunit (GNAT2) gene to 1p13 and mutation analysis in patients with Stargardt's disease. Am. J. Hum. Genet. (Supplement) 1994; 55:A230. Presented at the 44th Annual Meeting of the American Society of Human Genetics, Montreal, Quebec, Canada, October 18-22, 1994.
94. Morton CC, Bieber FR, Gutiérrez-Espeleta G, Johnson KR, Kovatch KA, Khetarpal U, Weremowicz S, Robertson NG: Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening. Presented at the annual meeting of the Association for Research in Otolaryngology, Tampa, FL, February 5-9, 1995.
95. Rein MS, Walters F, Weremowicz S, Morton CC: Cytogenetic abnormalities in uterine leiomyomata are associated with leiomyomata size. Presented at the Society for Gynecologic Investigation, Chicago, IL, March 15-18, 1995.
96. Zhao Y, Bjørbæk C, Weremowicz S, Morton CC, Moller DE: Cloning and functional characterization of RSK3: A novel pp90rsk isoform. Presented at the 77th annual meeting of The Endocrine Society, Washington, D.C., June 14-17, 1995.
97. Morton CC, Skvorak A, Yin Y, Weremowicz S, Bieber FR, Robertson NG: Cloning genes involved in hearing: A tissue specific library approach. Presented at the second conference on The Molecular Biology of Hearing and Deafness, Bethesda, MD, October 6-8, 1995.
98. Rehm H, Gutiérrez-Espeleta G, Sims KB, Garcia R, Priest JM, Keats BJB, Morton CC: Norrie gene mutation in a Costa Rican kindred with a novel phenotype including peripheral vascular disease. Presented at the second conference on The Molecular Biology of Hearing and Deafness, Bethesda, MD, October 6-8, 1995.
99. Khetarpal U, Morton CC: Dystrophin, cochlea and hearing loss. Presented at the second conference on The Molecular Biology of Hearing and Deafness, Bethesda, MD, October 6-8, 1995.
100. Khetarpal U, Morton CC: Tissue-specific alternative splicing of type II procollagen mRNAs during human fetal development and their role in inner ear morphogenesis and chondrogenesis. Presented at the second conference on The Molecular Biology of Hearing and Deafness, Bethesda, MD, October 6-8, 1995.
101. Rehm H, Gutiérrez-Espeleta G, Sims KB, Garcia R, Jimenez G, Priest JM, Keats BJB, Morton CC: Norrie gene mutation in a Costa Rican kindred with a novel phenotype including peripheral vascular disease. Am. J. Hum. Genet. (Supplement) 1995; 57:A249. Presented at the 45th Annual Meeting of the American Society of Human Genetics, Minneapolis, MN, October 24-28, 1995.
102. Schoenberg Fejzo M, Ashar H, Tkachenko A, Fletcher JA, Weremowicz S, Yoon S-J, Krauter KS, Kucherlapati R, Chada K, Morton CC: HMGI-C: An architectural factor at 12q14-15 involved in frequent chromosomal rearrangement in benign tumors. Am. J. Hum. Genet. (Supplement) 1995; 57:A4. Presented at the 45th Annual Meeting of the American Society of Human Genetics, Minneapolis, MN, October 24-28, 1995.
103. Skvorak A, Robertson NG, Yin Y, Weremowicz S, Bieber FR, Morton CC: Identification and characterization of genes expressed in the human fetal cochlea. Am. J. Hum. Genet. (Supplement) 1995; 57:A151. Presented at the 45th Annual Meeting of the American Society of Human Genetics, Minneapolis, MN, October 24-28, 1995.
104. Xing YP, Scherer SW, Tsui L-C, Morton CC: Identification of cosmids flanking the 7q breakpoint region in uterine leiomyomata. Am. J. Hum. Genet. (Supplement) 1995; 57:A80. Presented at the 45th Annual Meeting of the American Society of Human Genetics, Minneapolis, MN, October 24-28, 1995.
105. Basson CT, Schoenberg Fejzo M, MacRae CA, Morton CC, Seidman JG, Seidman CE: Identification, chromosomal localization and developmental cardiac expression of human ES/130. Presented at the 68th scientific sessions of the American Heart Association, Anaheim, CA, November 13-16, 1995.
106. Khetarpal U, Morton CC: Microanatomy of human fetal cochlea and genetic investigations in cochlear development. Submitted for presentation at the annual meeting of The American Laryngological, Rhinological and Otological Society, Inc. (The Trilogical Society).
107. Schoenberg Fejzo M, Ashar HR, Fletcher JA, Ishikawa M, Krauter KS, Nowak RA, Powell WL, Rein MS, Tkachenko A, Weremowicz S, Yoon S-J, Kucherlapati RS, Chada K, Morton CC: Architectural factor HMGI-C translocated in uterine leiomyomata and other benign tumors. Presented at the Chromosome 12 Workshop, University of Leuven, Leuven, Belgium, November 16-17, 1995 and the Symposium on Chromosome 12 Genes in Cancer, November 18, 1995.
108. Ashar H, Zhou X, Fejzo M, Tkachenko A, Benson K, Morton C, Chada K: The architectural factor HMGI-C and the multiple tumors whose breakpoints map to 12q14-15. Presented at the Symposium on Chromosome 12 Genes in Cancer, University of Leuven, Leuven, Belgium, November 16-17, 1995.
109. Morton CC: Many tumors and many genes: Genetics of uterine leiomyomata. Presented at the AAAS Annual Meeting and Science Innovation Exposition, Baltimore, MD, February 8-13, 1996.
110. Ashar H, Tkachenko A, Zhou X, Fejzo M, Benson K, Morton C, Chada K: Architectural factor HMGI-C and multiple tumors whose breakpoints map to 12q14-15. Submitted to HGM'96, Heidelberg, Germany, March 22-24, 1996.
111. Hsu LYF, Yu M, Neu RL, Van Dyke DL, Benn PA, Bradshaw CL, Shaffer LG, Higgins RR, Khodr GS, Morton CC, Wang H, Brothman AR, Chadwick D, Disteche CM, Jenkins LS, Kalousek DK, Pantzar TJ, Wyatt P: Rare trisomy mosaicism involving an autosome other than chromosome 13, 18, 20 and 21 diagnosed in amniocytes: karyotype/phenotype correlations. Am. J. Hum. Genet. (Supplement) 1996; 59:A40. Presented at the 46th annual meeting of the American Society of Human Genetics, San Francisco, CA, October 29-November 2, 1996.
112. Skvorak AB, Robertson NG, Yin Y, Weremowicz S, Bieber FR, Beier DR, Beisel KW, Morton CC: Characterization and fine mapping of antiquitin, a gene highly expressed in human fetal cochlea. Am. J. Hum. Genet. (Supplement) 1996; 59:A160. Presented at the 46th annual meeting of the American Society of Human Genetics, San Francisco, CA, October 29-November 2, 1996.
113. Morton CC, Robertson NG, Lennon GG, Skvorak AB: Human fetal cochlea expressed sequence tags: identification of possible positional candidate genes. Am. J. Hum. Genet. (Supplement) 1996; 59:A54. Presented at the 46th annual meeting of the American Society of Human Genetics, San Francisco, CA, October 29-November 2, 1996.
114. Rehm H, Gutiérrez-Espeleta G, Chen Z-Y, Corey DP, Halpin C, Sims KB, Morton CC: Further evaluation of a Costa Rican kindred with a novel phenotype including venous insufficiency: Expression of NDP mRNA. Am. J. Hum. Genet. (Supplement) 1996; 59:A281. Presented at the 46th annual meeting of the American Society of Human Genetics, San Francisco, CA, October 29-November 2, 1996.
115. Weremowicz S, Sandstrom M McH, Sandstrom DJ, Morton CC: Rapid prenatal diagnosis of aneuploidy by FISH of uncultured amniocytes: Experience with 154 cases using commercially available probes. Am. J. Hum. Genet. (Supplement) 1996; 59:A332. Presented at the 46th annual meeting of the American Society of Human Genetics, San Francisco, CA, October 29-November 2, 1996.
116. Khetarpal U, Morton CC: Investigations into the role of aggrecan and its alternatively spliced products in human fetal and cochlear development. Presented at the 1997 meeting of the Association for Research in Otolaryngology, St. Petersburg, FL, February 2-6, 1997.
117. Morton CC, Williams AJ, Collins T, Nowak RA: HMGI-C and HMGI(Y) expression in uterine leiomyomata: Dysregulation of architectural factors in a benign neoplasm. Presented at the seventh International Workshop on Chromosomes in Solid Tumors, Tucson, AZ, January 20-22, 1997.
118. Williams AJ, Powell WL, Collins T, Morton CC: HMGI(Y) expression in human uterine leiomyoma. Presented at the third annual Student Achievement Day, Boston University School of Medicine, Boston, MA, April 18, 1997.
119. Morton CC, Williams AJ, Quade BJ, Collins T, Nowak RA: HMGI-C and HMGI(Y) expression in uterine leiomyomata: Dysregulation of architectural factors in a benign neoplasm. Presented at the Fourth International Workshop on Chromosome 12, Nice, France, April 24-27, 1997.
120. Robertson NG, Skvorak AB, Heller S, Yin Y, Nguyen T, Weremowicz S, Kovatch KA, Battey JF, Bieber FR, Hudspeth AJ, Morton CC: Characterization of a novel cochlear gene in human, mouse and chicken: a positional candidate gene for the human deafness disorder, DFNA9. Am. J. Hum. Genet. (Supplement) 1997; 61:A181. Presented at the 47th annual meeting of the American Society of Human Genetics, Baltimore, MD, October 28-November 1, 1997.
121. Weremowicz S, Sandstrom MMcH, Sandstrom DJ, Miller WA, Gasparini RP, Morton CC: Prenatal diagnosis of aneuploidy by FISH of uncultured amniocytes: Advantages and diagnostic dilemmas. Am. J. Hum. Genet. (Supplement) 1997; 61:A143. Presented at the 47th annual meeting of the American Society of Human Genetics, Baltimore, MD, October 28-November 1, 1997.
122. Skvorak AB, Robertson NG, Weremowicz S, Lynch ED, Morton CC: An ancient conserved gene expressed in the human inner ear: Mapping of antiquitin and four antiquitin-like loci. Am. J. Hum. Genet. (Supplement) 1997; 61:A183. Presented at the 47th annual meeting of the American Society of Human Genetics, Baltimore, MD, October 28-November 1, 1997.
123. Quade BJ, Williams AJ, Collins T, Nowak RA, Morton CC: HMGIC and HMGIY expression in uterine leiomyomata: Dysregulation of architectural factors in a benign neoplasm. Am. J. Hum. Genet. (Supplement) 1997; 61:A79. Presented at the 47th annual meeting of the American Society of Human Genetics, Baltimore, MD, October 28-November 1, 1997.
124. den Hollander A, van Driel M, van Limpt V, de Kok Y, van de Pol D, Hoyng C, Deutman A, Morton C, Cremers F: Isolation of novel retina-, retinal pigment epithelium- and cochlea-specific cDNAs through suppression subtractive hybridization. Am. J. Hum. Genet. (Supplement) 1997; 61:A234. Presented at the 47th annual meeting of the American Society of Human Genetics, Baltimore, MD, October 28-November 1, 1997.
125. Higgs DR, Ko JL, Syed FA, Kheraj R, Horiuchi T, Khan S, Yu W, Lim B, Weremowicz S, Morton CC, Adra CN: Human RhoGDIg, novel GDP-dissociation inhibitor for Rho proteins: Function, expression, complete sequence, genomic organization and chromosomal localization. Am. J. Hum. Genet. (Supplement) 1997; 61:A174. Presented at the 47th annual meeting of the American Society of Human Genetics, Baltimore, MD, October 28-November 1, 1997.
126. Scott DA, Greinwald JH, Jr., Marietta JR, Swiderski RE, Carmi R, Ramesh A, Kraft ML, Elbedour K, Yairi Y, Skvorak AB, Srikumari Srisailapathy CR, Morton CC, Smith RJH, Sheffield VC: Identification and mutation analysis of two cochlear expressed genes at the DFNB7/11 locus on chromosome 9q. Am. J. Hum. Genet. (Supplement) 1997; 61:A293. Presented at the 47th annual meeting of the American Society of Human Genetics, Baltimore, MD, October 28-November 1, 1997.
127. Quade BJ, Weremowicz S, Nowak R, Vanni R, Dal Cin P, Morton CC: HMGI-C dysregulation by translocation t(12;14) in uterine leiomyoma (UL) is not mediated by chimeric gene product formation. Submitted for presentation at the annual meeting of the United States and Canadian Academy of Pathology, Boston, MA, March 2-4, 1998.
128. Vaughan CJ, Hahn RT, Girardi LN, Lee H, Goldstein MM, Morton CC, Basson CT: Clinical and genetic analysis of cardiac lipoma and systemic lipomatosis. Submitted for presentation at the 71st Scientific Sessions of the American Heart Association.
129. Morton CC, Gross KL: HMGIC and HMGIY rearrangements as secondary events in the genesis of uterine leiomyomas: evidence for the genetic basis of fibroids. Presented at the First International Workshop on the Role of High Mobility Group Proteins in Human Disease, Bremen, Germany, June 14-16, 1998.
130. Nomura H, Turco AE, Pei Y, Kalaydjieva L, Weremowicz S, Ji W, Morton CC, Meisler MH, Reeders ST, Zhou J: Identification of polycystin-2B, a novel polycystin family member. Submitted for presentation at the American Society of Nephrology.
131. Robertson NG, Lu L, Heller S, Merchant SN, Eavey RD, McKenna M, Nadol, JB Jr., Miyamoto RT, Linthicum FH Jr., Lubianca Neto JF, Hudspeth AJ, Seidman CE, Seidman JG, Morton CC: Mutations in a novel cochlear gene COCH5B2 cause DFNA9, a human nonsyndromic sensorineural deafness with vestibular dysfunction. Presented at The Molecular Biology of Hearing and Deafness, Bethesda, MD, Oct. 8-11, 1998.
132. Skvorak AB, Weng Z, Yee AJ, Robertson NG, Morton CC: Human cochlear expressed sequence tags provide insight into cochlear gene expression and identify candidate genes for deafness. Presented at The Molecular Biology of Hearing and Deafness, Bethesda, MD, Oct. 8-11, 1998.
133. Rehm HL, Morton CC: Localization of the norrin receptor using a fusion protein of norrin, the protein responsible for Norrie disease. Presented at The Molecular Biology of Hearing and Deafness, Bethesda, MD, Oct. 8-11, 1998.
134. Weremowicz S, Sornberger K, Dal Cin P, Vanni R, Morton CC: Characterization of HMGIC gene rearrangements in uterine leiomyomas by fluorescence in situ hybridization (FISH). Am. J. Hum. Genet. (Supplement) 1998; 63:A499. Presented at the 48th annual meeting of the American Society of Human Genetics, Denver, CO, Oct. 27-31, 1998.
135. Pedeutour F, Quade BJ, Sornberger KS, Ligon AH, Weremowicz S, Morton CC: Ring chromosome and complex rearrangement involving chromosomes 7, 8, 10, 11, 12 and 14 in a case of uterine lipoleiomyoma. Am. J. Hum. Genet. (Supplement) 1998; 63:A445. Presented at the 48th annual meeting of the American Society of Human Genetics, Denver, CO, Oct. 27-31, 1998.
136. Robertson NG, Lu L, Heller S, Merchant SN, Eavey RD, McKenna M, Nadol, JB Jr., Miyamoto RT, Linthicum FH Jr., Lubianca Neto JF, Hudspeth AJ, Seidman CE, Seidman JG, Morton CC: Mutations in a novel cochlear gene COCH5B2 cause DFNA9, a human nonsyndromic sensorineural deafness with vestibular dysfunction. Am. J. Hum. Genet. (Supplement) 1998; 63:A272. Presented at the 48th annual meeting of the American Society of Human Genetics, Denver, CO, Oct. 27-31, 1998.
137. Gattás GJF, Quade BJ, Nowak RA, Morton CC: HMGIC expression in human tissues and in uterine leiomyomata. Am. J. Hum. Genet. (Supplement) 1998; 63:A370. Presented at the 48th annual meeting of the American Society of Human Genetics, Denver, CO, Oct. 27-31, 1998.
138. Rehm HL, Morton CC: An expression cloning approach to identify a receptor for norrin, the protein responsible for Norrie disease. Am. J. Hum. Genet. (Supplement) 1998; 63:A1085. Presented at the 48th annual meeting of the American Society of Human Genetics, Denver, CO, Oct. 27-31, 1998.
139. Nucci MR, Weremowicz S, Sornberger KS, Morton CC, Quade BJ: Chromosomal translocation t(8;12) induces aberrant HMGIC expression in vulvar aggressive angiomyxoma. Presented at the 88th annual meeting of the United States and Canadian Academy of Pathology, San Francisco, CA, March 20-26, 1999.
140. Quade BJ, Pedeutour F, Weremowicz S, Sornberger KS, Ligon AH, Morton CC: Ring chromosome and complex rearrangement involving chromosomes 7, 8, 10, 11, 12 and 14 in uterine lipoleiomyoma. Presented at the 88th annual meeting of the United States and Canadian Academy of Pathology, San Francisco, CA, March 20-26, 1999.
141. Hampton LL, Morell RJ, Morton CC, Battey JF: Identification of novel sequences expressed in the human fetal cochlea. Presented at the annual meeting of the Association for Research in Otolaryngology, St. Petersburg Beach, FL, Feb. 14-18, 1999.
142. Dangond F, Foernzler D, Weremowicz S, Morton CC, Beier DR, Gullans SR: Cloning and chromosomal mapping of murine histone deacetylase 3 (mHDAC3). Accepted for presentation at the Experimental Biology meeting, Washington, DC, April 18, 1999.
143. Gross KL, Morton CC, Stewart EA: Finding genes for uterine fibroids. Submitted for presentation at the 55th annual meeting of the American Society for Reproductive Medicine, Toronto, Ontario, Canada, September 25-30, 1999.
144. Ligon AH, Bruns GAP, Gusella JF, Korf BR, Maas RL, MacDonald ME, Michelson AM, Quade BJ, Morton CC: DGAP: Developmental genome anatomy project. Am. J. Hum. Genet. (Supplement) 1999; 65:A366. Presented at the 49th annual meeting of the American Society of Human Genetics, San Francisco, CA, Oct. 19-23, 1999.
145. Robertson NG, Lin JS, Lee C, Rehm HL, Shahsafaei A, Aster JC, Morton CC: Protein expression of COCH, the DFNA9 sensorineural deafness gene, in human fetal cochlea and vestibule. Am. J. Hum. Genet. (Supplement) 1999; 65:A487. Presented at the 49th annual meeting of the American Society of Human Genetics, San Francisco, CA, Oct. 19-23, 1999.
146. Quade BJ, Getman M, Wang T-Y, Weremowicz S, Dal Cin P, Morton CC: Exploring the dysregulation of HMGIC in uterine leiomyomata with t(12;14). Am. J. Hum. Genet. (Supplement) 1999; 65:A317. Presented at the 49th annual meeting of the American Society of Human Genetics, San Francisco, CA, Oct. 19-23, 1999.
147. Nucci MR, Weremowicz S, Tallini G, Sornberger K, Morton CC, Quade BJ: t(8;12) induces aberrant HMGIC expression in aggressive angiomyomam of the vulva. Am. J. Hum. Genet. (Supplement) 1999; 65:A313. Presented at the 49th annual meeting of the American Society of Human Genetics, San Francisco, CA, Oct. 19-23, 1999.
148. Caldwell GM, Day CD, Cooper PR, Eddy RL, Hejtmancik F, Evans GA, Smith RJH, Morton CC, Higgins MJ, Shows TB: Transcript map of the Usher syndrome 1C gene locus on chromosome 11p14-15.1. Am. J. Hum. Genet. (Supplement) 1999; 65:A223. Presented at the 49th annual meeting of the American Society of Human Genetics, San Francisco, CA, Oct. 19-23, 1999.
149. Morton CC, Mutter GL, Fitzgerald J, Sornberger K, Quade BJ: Gene expression analysis of uterine leiomyomata and myometrium using oligonucleotide microarrays: A model system for the evaluation of genetic effects on gene expression. Presented at the International Workshop on Chromosomes in Solid Tumors, Tucson, AZ, Jan. 30-Feb. 1, 2000.
150. Robertson N, Lin J, Lee C, Rehm H, Aster J, Adams J, Morton C: Localization in human cochlea and vestibule of the cochlin protein, mutated in DFNA9 sensorineural deafness. Presented at the 23rd midwinter research meeting of the Association for Research in Otolaryngology, St. Petersburg Beach, FL, Feb. 20-24, 2000.
151. Morton CC, Mutter GL, Fitzgerald J, Sornberger K, Quade BJ: Gene expression analysis of uterine leiomyomata and myometrium using oligonucleotide microarrays: A model system for the evaluation of genetic effects on gene expression. Presented at the Workshop on The Role of HMG Proteins in Chromatin Structure, Gene Expression and Neoplasia, National Institutes of Health, Bethesda, MD, May 1-2, 2000.
152. Lemyre E, LigonAH, Bruns GAP, Gusella JF, Herrick SR, Korf BR, Lewis J, Maas RL, MacDonald ME, Michelson AM, Quade BJ, Morton CC: “Developmental genome anatomy project”: Nouvelle stratégie d’identification de gènes impliqués dans le développement humain. Presented at Reseau de Medecine Génétiques Applique, Troisièmes Journées Génétiques, Montréal, Canada, May 18-19, 2000.
153. Gross K, Morton C, Stewart E: Finding genes for uterine fibroids. Presented at the 48th annual clinical meeting of The American College of Obstetricians and Gynecologists, San Francisco, CA, May 20-24, 2000.
154. Robertson NG, Lin JS, Heller S, Resendes BL, Weremowicz S, Denis CS, Bell AM, Adams JC, Hudspeth AJ, Morton CC: Identification and characterization of a novel cochlear gene, OTOR, and localization of its encoded protein, otoraplin. Am. J. Hum. Genet. (Supplement) 2000; 67:A928. Presented at the 50th annual meeting of the American Society of Human Genetics, Philadelphia, PA, October 3-7, 2000.
155. Weremowicz S, Sandstrom DJ, Thomas A, Sandstrom MMcH, Morton CC: Chromosome analysis on fetal tissues: A revised protocol employing interphase FISH improves the success rate. Am. J. Hum. Genet. (Supplement) 2000; 67:A835. Presented at the 50th annual meeting of the American Society of Human Genetics, Philadelphia, PA, October 3-7, 2000.
156. Lemyre E, Bruns GAP, Gusella JF, Korf BR, Herrick SR, Ligon AH, Lewis J, Maas RL, MacDonald ME, Michelson AM, Quade BJ, Morton CC: Developmental genome anatomy project: Two breakpoints localized in BAC clones. Am. J. Hum. Genet. (Supplement) 2000; 67:A1413. Presented at the 50th annual meeting of the American Society of Human Genetics, Philadelphia, PA, October 3-7, 2000.
157. Resendes BL, Robertson NG, Szustakowski JD, Resendes RJ, Weng Z, Morton CC: Characterization of cochlear ESTs for gene discovery in the auditory system. Am. J. Hum. Genet. (Supplement) 2000; 67:A2154. Presented at the 50th annual meeting of the American Society of Human Genetics, Philadelphia, PA, October 3-7, 2000.
158. Dal Cin P, Neskey DM, Weremowicz S, Morton CC, Quade B: Intravenous leiomyomatosis: Is there a genetic link with uterine leiomyoma? Presented at the annual meeting of the United States and Canadian Academy of Pathology, Atlanta, GA, March 3-9, 2001.
159. Rehm HL, Zhang D-S, Chen Z-Y, Morton CC, Corey DP: Fluorescent imaging of blood vessels in the Norrie disease mouse model reveals defects in the vascular structures of the cochlea and retina. Presented at the 24th midwinter research meeting of the Association for Research in Otolaryngology, St. Petersburg Beach, FL, Feb. 3-8, 2001.
160. Robertson NG, Lin JS, Heller S, Resendes BL, Weremowicz S, Kristiansen AG, McKenna MJ, Adams JC, Morton CC: Characterization of a novel cochlear gene, OTOR, homologous to CDRAP/MIA, and localization of its encoded protein, otoraplin. Presented at the 24th midwinter research meeting of the Association for Research in Otolaryngology, St. Petersburg Beach, FL, Feb. 3-8, 2001.
161. Wayne S, Robertson N, DeClau F, Chen N, Verhoeven K, Prasad S, Morton C, Ryan A, Van Camp G, Smith R: Mutations in the transcriptional activator EYA4 cause late-onset deafness at the DFNA10 locus. Presented at the 24th midwinter research meeting of the Association for Research in Otolaryngology, St. Petersburg Beach, FL, Feb. 3-8, 2001.
162. Robertson NG, Resendes BL, Lin JS, Lee C, Aster JC, Adams JC, Morton CC: Inner ear localization of mRNA and protein products of COCH, mutated in the sensorineural deafness and vestibular disorder, DFNA9. Presented at the conference on Molecular Biology of Hearing and Deafness, Bethesda, MD, Oct. 4-7, 2001.
163. Resendes BL, Robertson NG, Szustakowski JD, Resendes RJ, Weng Z, Morton CC: Gene discovery in the auditory system: Characterization of additional cochlear expressed sequences. Presented at the conference on Molecular Biology of Hearing and Deafness, Bethesda, MD, Oct. 4-7, 2001.
164. Rehm HL, Chen ZY, Zhang DS, Brown MC, Morton CC, Corey DP: Mouse model of Norrie disease suggests involvement of the Ndp gene in function of the stria vascularis and spiral ganglion of the cochlea. Presented at the conference on Molecular Biology of Hearing and Deafness, Bethesda, MD, Oct. 4-7, 2001.
165. Giersch ABS, Hamaker S, Quade BJ, Kuo FC, Morton CC: Development of an inner ear cDNA microarray. Presented at the conference on Molecular Biology of Hearing and Deafness, Bethesda, MD, Oct. 4-7, 2001.
166. Alagramam KN, Yuan H, Kuehn MH, Murcia CL, Wayne S, Srisailpathy CRS, Lowry RB, Knaus R, Laer LV, Bernier FP, Schwartz S, Lee C, Morton CC, Mullins RF, Ramesh A, van Camp G, Hagemen GS, Smith RJH: Mutations in the protocadherin PCDH15 cause Usher syndrome type 1F. Presented at the conference on Molecular Biology of Hearing and Deafness, Bethesda, MD, Oct. 4-7, 2001.
167. Wayne S, Robertson NG, DeClau F, Chen N, Verhoeven K, Prasad S, Morton CC, Ryan AF, Van Camp G, Smith RJH: Mutations in the transcriptional activators EYA1 and EYA4 cause syndromic and nonsyndromic hearing loss. Presented at the conference on Molecular Biology of Hearing and Deafness, Bethesda, MD, Oct. 4-7, 2001.
168. Robertson NG, Resendes BL, Lin JS, Lee C, Aster JC, Adams JC, Morton CC: Inner ear localization of mRNA and protein products of COCH, mutated in the sensorineural deafness and vestibular disorder, DFNA9. Am. J. Hum. Genet. (Supplement) 2001; 69:348. Presented at the 51st annual meeting of the American Society of Human Genetics, San Diego, CA, Oct. 12-16, 2001.
169. Higgins AW, Lemyre E, Bruns GAP, Farra C, Gusella JF, Korf BR, Herrick SR, Ligon AH, Lewis J, Maas RL, MacDonald ME, Michelson AM, Quade BJ, Rooryck C, Tihys F, Morton CC: Developmental Genome Anatomy Project: Breakpoint localization updates. Am. J. Hum. Genet. (Supplement) 2001; 69:334. Presented at the 51st annual meeting of the American Society of Human Genetics, San Diego, CA, Oct. 12-16, 2001.
170. Neskey DM, Ligon AH, Quade BJ, MortonCC: Polyomavirus large T antigen/MMTV transgenic mice as a model of uterine leiomyomata. Am. J. Hum. Genet. (Supplement) 2001; 69:267. Presented at the 51st annual meeting of the American Society of Human Genetics, San Diego, CA, Oct. 12-16, 2001.
171. Lee C, Murray MF, Miron PM, Irons M, Wilkins-Haug LE, Morton CC: Sequential M-FISH and Rx-FISH in delineating the origin of ambiguous chromosome regions/fragments. Am. J. Hum. Genet. (Supplement) 2001; 69:331. Presented at the 51st annual meeting of the American Society of Human Genetics, San Diego, CA, Oct. 12-16, 2001.
172. Greinwald JH, Pilipenko V, Guo Y, Choo DI, Ramesh A, Giersch AB, Morton CC, Nichols WC, Smith RJ: Identification and characterization of cochlear expressed genes in the DFNB17 interval. Am. J. Hum. Genet. (Supplement) 2001; 69:543. Presented at the 51st annual meeting of the American Society of Human Genetics, San Diego, CA, Oct. 12-16, 2001.
173. Huang T, Weremowicz S, Cox G, Lin AE, Golden W, Feldman GL, Vermeulen S, Moog U, Schrander-Stumpel C, Morton CC, Seidman JG, Seidman CE: Variable cardiac phenotypes in chromosome 4p- syndroome with dHAND deletion. Am. J. Hum. Genet. (Supplement) 2001; 69:553. Presented at the 51st annual meeting of the American Society of Human Genetics, San Diego, CA, Oct. 12-16, 2001.
174. Higgins AW, Lemyre E, Bruns GAP, Farra C, Gusella JF, Korf BR, Herrick SR, Leach NT, Ligon AH, Lewis J, Maas RL, MacDonald ME, Michelson AM, Quade BJ, Rooryck C, Tihy F, Williamson RE, Morton CC: Developmental Genome Anatomy Project: Six breakpoints localized in BAC clones. Genet. Med. 2002;3(3). Presented at the annual meeting of the American College of Medical Genetics, New Orleans, LA, Mar. 14-17, 2002.
175. Morton CC, Dal Cin P, Neskey DM, Weremowicz S, Quade BJ: Are fusion transcripts involving HMGA2 a common molecular mechanism in uterine leiomyomata with rearrangements in 12q15? Presented at the Third International Workshop on HMGA Proteins in Cell Differentiation and Transformation, Napoli, Italy, May 23-24, 2002
176. Neskey DM, Dal Cin P, Weremowicz S, Quade BJ, Morton CC: Understanding the molecular mechanism of dysregulated HMGA2 expression in uterine leiomyomata with 12q15 rearrangements. Am. J. Hum. Genet. (Supplement) 2002; 71:200. Presented at the 52nd annual meeting of the American Society of Human Genetics, Baltimore, MD, Oct. 15-19, 2002.
177. Herrick SR, Bosco AF, Bruns GAP, Eisenman R, Farra C, Ferguson HL, Gusella JF, Higgins AW, Korf BR, Ligon AH, Leach NT, Lemyre E, Kim HG, Maas RL, MacDonald ME, Michaud S, Michelson AM, Quade BJ, Williamson RE, Morton CC: Developmental genome anatomy project (DGAP): Mapping genes that cause congenital anomalies. Am. J. Hum. Genet. (Supplement) 2002; 71:297. Presented at the 52nd annual meeting of the American Society of Human Genetics, Baltimore, MD, Oct. 15-19, 2002.
178. Leach NT, Michaud S, Quade BJ, Ligon AH, Michelson AM, Maas RL, Korf BR, Herrick SR, Ferguson HL, Morton CC: Characterization of a t(X;2)(p11.2;q37)de novo associated with congenital anomalies: Positional identification of disrupted genes. Am. J. Hum. Genet. (Supplement) 2002; 71:199. Presented at the 52nd annual meeting of the American Society of Human Genetics, Baltimore, MD, Oct. 15-19, 2002.
179. Giersch ABS, Lyall K, Hamaker S, Quade BJ, Morton CC: Development of an inner ear cDNA microarray. Am. J. Hum. Genet. (Supplement) 2002; 71:390. Presented at the 52nd annual meeting of the American Society of Human Genetics, Baltimore, MD, Oct. 15-19, 2002.
180. Williamson RE, Morton CC: Cytogenetic approaches to finding auditory genes. Am. J. Hum. Genet. (Supplement) 2002; 71:289. Presented at the 52nd annual meeting of the American Society of Human Genetics, Baltimore, MD, Oct. 15-19, 2002.
181. Miron PM, Herrick S, Morton CC, Stoler J, Wilkins-Haug L, Weremowicz S: Custom probes for PGD of acrocentric chromosome rearrangements: Use of the BAC Resource Consortium. Am. J. Hum. Genet. (Supplement) 2002; 71:309. Presented at the 52nd annual meeting of the American Society of Human Genetics, Baltimore, MD, Oct. 15-19, 2002.
182. Chen ZY, Morton CC, Corey DP: Expression profile of the human inner ear genes and the identification of candidate genes for genetic deafness. Am. J. Hum. Genet. (Supplement) 2002; 71:311. Presented at the 52nd annual meeting of the American Society of Human Genetics, Baltimore, MD, Oct. 15-19, 2002.
183. Robertson NG, Patriub V, Hanmaker SA, Aster JA, Morton CC: Secretion and subcellular localization of wild-type cochlin, and of mutants causing the sensorineural deafness and vestibular disorder, DFNA9. Am. J. Hum. Genet. (Supplement) 2002; 71:512. Presented at the 52nd annual meeting of the American Society of Human Genetics, Baltimore, MD, Oct. 15-19, 2002.
184. Robertson NG, Hamaker SA, Patriub V, Aster JC, Morton CC: Processing and secretion of normal and mutated cochlin, the affected protein in the sensorineural deafness and vestibular disorder, DFNA9. ARO abstracts 26:58, 2003. Presented at the 25th midwinter research meeting of the Association for Research in Otolaryngology, Daytona Beach, FL, Feb. 23-27, 2003.
185. Chen, Z-Y, Morton CC, Corey DP: Expression profile of the human inner ear genes and the identification of candidate genes for genetic deafness. Presented at the 25th midwinter research meeting of the Association for Research in Otolaryngology, Daytona Beach, FL, Feb. 23-27, 2003.
186. Morton CC, Robertson NG, Resendes BL, Giersch ABS: Gene discovery in the auditory system using a tissue specific approach. Genet. Med. 5:254, 2003. Presented at the 34th annual March of Dimes Clinical Genetics Conference, San Diego, CA, Mar. 14, 2003.
187. Morton CC, Herrick SR, Korf BR, Leach NT, Ligon AH, Michaud S, Williamson RE, DGAP Investigators: Developmental genome anatomy project (DGAP): Identification of critical developmental genes by breakpoint mapping. Genet. Med. 5:201, 2003. Presented at the annual meeting of American College of Medical Genetics, San Diego, CA, Mar. 13-16, 2003.
188. Dal Cin P, Christacos NC, Morton CC, Quade BJ: Cellular leiomyoma: a genetically distinct entity among benign uterine tumors. Mod. Pathol. 2002; 16:197A. Presented at the annual meeting of the United States and Canadian Academy of Pathology, Washington, DC, Mar. 22-27, 2003.
189. Iannaconne A, Breuerr DK, Wang XF, Kuo SF, Normando EM, Cosgrove D, Baldi A, Morton CC, Swaroop A, Jablonski MM: Clinical and immunohistochemical evidence for an X-linked retinitis pigmentosa syndrome with recurrent infections and hearing loss in association with an RPGR mutation. Presented at the annual meeting of the Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, May 4-9, 2003.
190. Dettori T, Frau DV, Lee C, Morton CC, Vanni R: CGH and array based CGH on B-CPAP human papillary thyroid carcinoma derived cell line. Presented at the annual meeting of the European Cytogeneticists Association, 2003.
191. Moore SDP, Herrick SR, Ince T, Dal Cin P, Kleinman M, Morton CC, Quade BJ: Cytogenetic characterization of uterine leiomyomata with t(10;17) involve the histone acetyltransferase MORF. Am. J. Hum. Genet. (Supplement) 2003; 73:223. Presented at the 53rd annual meeting of the American Society of Human Genetics, Los Angeles, CA, Nov. 4-8, 2003.
192. Leach NT, Bruns GAP, Eisenman R, Ferguson HL, Gusella JF, Harris DJ, Herrick SR, Higgins AW, Ligon AH, Kim HG, Lu W, Maas RL, Michaud S, Michelson AM, Moore SD, Peters RE, Quade BJ, Qunitero-Rivera F, Williamson RE, Morton CC: Developmental Genome Anatomy Project (DGAP): Identification of genes involved in human development. Am. J. Hum. Genet. (Supplement) 2003; 73:306. Presented at the 53rd annual meeting of the American Society of Human Genetics, Los Angeles, CA, Nov. 4-8, 2003.
193. Christacos N, Dal Cin P, Morton CC, Quade BJ: Cellular leiomyoma: A genetically distinct entity among benign uterine tumors. Am. J. Hum. Genet. (Supplement) 2003; 73:220. Presented at the 53rd annual meeting of the American Society of Human Genetics, Los Angeles, CA, Nov. 4-8, 2003.
194. Weremowicz S, Racowsky C, Sandstrom DJ, Nureddin A, Jackson KV, Wilkins-Haug LE, Morton CC, Miron PM: Preimplantation genetic diagnosis (PGD) for couples at risk of X-linked disease and for balanced translocation carriers. Am. J. Hum. Genet. (Supplement) 2003; 73:596. Presented at the 53rd annual meeting of the American Society of Human Genetics, Los Angeles, CA, Nov. 4-8, 2003.
195. Williamson RE, Lu W, Michaud S, Peters RE, Quade BJ, Michelson AM, Maas RL, Morton CC: Cytogenetic approaches to finding auditory genes. Am. J. Hum. Genet. (Supplement) 2003; 73:298. Presented at the 53rd annual meeting of the American Society of Human Genetics, Los Angeles, CA, Nov. 4-8, 2003.
196. Treon SP, Braverman E, Branagan AR, Masotta S, Listewnik M, Morton C, Lee C: Deletions in 6q21-22 are commonly present in patients with familial and non-familial Waldenstrom’s macroglobulinemia and IgM monoclonal gammopathy of unknown signficance (MGUS). Presented at the annual meeting of the American Society of Hematology, San Diego, CA, Dec. 5-8, 2003.
197. Ferguson HL, Harris, DJ, Bruns GAP, Eisenman R, Gusella JF, Herrick SR, Higgins AW, Leach NT, Ligon AH, Kim HG, Lu W, Maas RL, Michaud S, Michelson AM, Moore SD, Peters RE, Quade BJ, Qunitero-Rivera F, Williamson RE, Morton CC: Developmental Genome Anatomy Project (DGAP): In search of genes critical for human development. Presented at the 2003 Annual Meeting of NERGG, Durham, NH, December 2003.
198. Resendes BL, Kuo SF, Robertson NG, Giersch ABS, Honrubia D, Ohara O, Adams JC, Morton CC: Isolation from cochlea of a novel human intronless gene with predominant fetal expression. Presented at the 26th midwinter research meeting of the Association for Research in Otolaryngology, Daytona Beach, FL, Feb. 22-26, 2004.
199. Giersch ABS, O’Donovan AB, Lyall K, Hamaker S, Quade BJ, Morton CC: Development of an inner ear cDNA microarray. Presented at the 26th midwinter research meeting of the Association for Research in Otolaryngology, Daytona Beach, FL, Feb. 22-26, 2004.
200. Makishima T, Rodriguez CI, Robertson NG, Morton CC, Stewart CL, Griffith AJ: Normal auditory function associated with a partial genomic deletion of mouse Coch. Presented at the 26th midwinter research meeting of the Association for Research in Otolaryngology, Daytona Beach, FL, Feb. 22-26, 2004.
201. Moore SDP, Herrick SR, Ince T, Dal Cin P, Kleinman M, Morton CC, Quade BJ: Chromosome 10 rearrangements in uterine leiomyomata involve the histone acetyltransferase MORF. Presented at the annual meeting of the United States and Canadian Academy of Pathology, Inc., Vancouver, BC, Mar. 8, 2004.
202. Veugelers M, Bressan M, McDermott DA, Weremowicz S, Morton CC, Mabry CC, Lefaivre J-F, Zunamon A, Chaudron J-M, Basson CT: Human mutation of perinatal myosin causes a Carney complex variant. Submitted for presentation at the 2004 annual meeting of the American Heart Association.
203. Lewis J, Ferguson HL, Bruns GAP, Donovan DJ, Eisenman RE, Gusella JF, Harris DJ, Herrick SR, Higgins AW, Leach NT, Ligon AH, Kim H-G, Lu W, Maas RL, Michaud S, Michelson AM, Moore SD, Peters RE, Quade BJ, Qunitero-Rivera F, Williamson RE, Morton CC: The Developmental Genome Anatomy Project (DGAP): In search of genes critical for human development. Presented at the National Center on Birth Defects and Developmental Disabilities Conference, Washington, DC, July 26-28, 2004.
204. Robertson NG, Sivakumaran TA, Hamaker SA, Morton CC: Development of a COCH "knock-in" mouse model for DFNA9. Presented at the Molecular Biology of Hearing and Deafness, Bethesda, MD, Sept. 29-Oct. 3, 2004.
205. Williamson RE, Lu W, Morton CC: Cytogenetic approaches to finding auditory genes. Presented at the Molecular Biology of Hearing and Deafness, Bethesda, MD, Sept. 29-Oct. 3, 2004.
206. Kocher K, Morton CC: Syndromic hearing loss associated with a familial paracentric inversion of the long arm of chromosome 7. Presented at the Molecular Biology of Hearing and Deafness, Bethesda, MD, Sept. 29-Oct. 3, 2004.
207. Sivakumaran TA, Resendes BL, Robertson NG, Giersch ABS, Morton CC: Characterization of a novel 3' end COL9A1 expressed sequence in cochlea and other tissues. Presented at the Molecular Biology of Hearing and Deafness, Bethesda, MD, Sept. 29-Oct. 3, 2004.
208. Giersch ABS, Kasper AB, Lyall K, Hamaker S, Quade BJ, Morton CC: Development of an inner ear cDNA microarray. Presented at the Molecular Biology of Hearing and Deafness, Bethesda, MD, Sept. 29-Oct. 3, 2004.
209. Ferguson H, Gusella J, Harris D, Ligon A, Kim H, Lu W, Maas R, Quade B, Morton C: The Developmental Genome Anatomy Project (DGAP): In search of genes critical for human development. Presented at the 23rd Annual Education Conference 2004, National Society of Genetic Counselors, Washington, DC, Oct. 7-11, 2004.
210. Williamson RE, Lu W, Morton CC: Cytogenetic approaches to finding auditory genes. Am. J. Hum. Genet. (Supplement) 2004; 75:74. Presented at the 54th annual meeting of the American Society of Human Genetics, Toronto, Ontario, Oct. 26-30, 2004.
211. Moore SDP, Dal Cin P, Quade BJ, Herrick SR, Ince T, Parisi M, Mealiffe M, Harris DJ, Ferguson HL, Strehl S, Ligon AH, Kleinman M, Kucherlapati R, Morton CC: Tumor Genome Anatomy Project (TGAP): Gene discovery in tumors in the genome era. Am. J. Hum. Genet. (Supplement) 2004; 75:79. Presented at the 54th annual meeting of the American Society of Human Genetics, Toronto, Ontario, Oct. 26-30, 2004.
212. Kocher K, Morton CC: Syndromic hearing loss associated with a familial paracentric inversion of the long arm of chromosome 7. Am. J. Hum. Genet. (Supplement) 2004; 75:179. Presented at the 54th annual meeting of the American Society of Human Genetics, Toronto, Ontario, Oct. 26-30, 2004.
213. Lu W, Peters RE, Ferguson HL, Quintero-Rivera F, Eisenman R, Sanlaville D, Feather SA, Woolf AS, Eccles MR, Harris DJ, Ligon AH, Quade BJ, Bruns GAP, Gusella J, Morton CC, Maas RL: Disruption of ROBO2 in a patient with vesicoureteral reflux (VUR). Am. J. Hum. Genet. (Supplement) 2004; 75:180. Presented at the 54th annual meeting of the American Society of Human Genetics, Toronto, Ontario, Oct. 26-30, 2004.
214. Quintero-Rivera F, Bruns GAP, Donovan DJ, Eisenman R, Ferguson HL, Harris DJ, Higgins AW, Ligon AH, Kim HG, Kocher KM, Lu W, Maas RL, Moore SD, Leach NT, Peters R, Quade BJ, Saadi I, Williamson RE, Morton CC, Gusella JF: Developmental Genome Anatomy Project (DGAP): In search of genes critical for human development. Am. J. Hum. Genet. (Supplement) 2004; 75:197. Presented at the 54th annual meeting of the American Society of Human Genetics, Toronto, Ontario, Oct. 26-30, 2004.
215. Lu W, Peters R, Ferguson H, Quintero F, Sanlaville D, Feather S, Woolf A, Harris D, Quade B, Gusella J, Morton C, Maas R. Disruption of ROBO2 is associated with Vesicoureteral Reflux. J. Am. Soc. Nephrol. 2004; 15:SA-FC051. Presented at the annual meeting of the American Society of Nephrology, St. Louis, MO, Oct. 29-Nov. 1, 2004.
216. Kuo SF, Lu W, Pandya A, Ukomadu C, Adams JC, Morton CC: Genetic and functional characterization of PFET1, an abundantly expressed fetal cochlear transcript with high GC-content. Presented at the 28th Midwinter Research Meeting of the Association for Research in Otolaryngology, New Orleans, LA, Feb. 19-24, 2004.
217. Robertson NG, Sivakumaran T, Hamaker S, Morton CC: Development of a COCH “knock-in” mouse model for DFNA9. Presented at the 28th Midwinter Research Meeting of the Association for Research in Otolaryngology, New Orleans, LA, Feb. 19-24, 2004.
218. Moore SDP, Herrick SR, Ince TA, Kleinman MS, Dal Cin P, Morton CC, Quade BJ: Uterine leiomyomata with t(10;17) disrupt the histone acetyltransferase MYST4. Presented at Advances in Uterine Leiomyoma Research: 2nd NIH International Congress, Bethesda, MD, Feb. 24-25, 2005.
219. Morton CC: Cytogenetic approaches to gene discovery in the genome era. Presented at the DECIPHER Symposium, The Sanger Center, Hinxton Cambridge, UK, June 23-25, 2005.
220. Robertson NG, Sivakumaran TA, Hamaker SA, Morton CC: A Coch “knock-in” mouse model for DFNA9 deafness. Presented at the conference “The Mouse as an Instrument for Ear Research II”, The Jackson Laboratory, Bar Harbor, ME, Oct. 1-4, 2005.
221. Giersch ABS, Kasper AO, Lyall K, Hamaker S, Quade BJ, Morton CC: Development of an inner ear cDNA microarray. Presented at the conference “The Mouse as an Instrument for Ear Research II”, The Jackson Laboratory, Bar Harbor, ME, Oct. 1-4, 2005.
222. Robertson NG, Sivakumaran TA, Hamaker SA, Morton CC: A Coch “knock-in” mouse model for DFNA9 deafness. Am. J. Hum. Genet. (Supplement) 2005; 77:360. Presented at the 55th annual meeting of the American Society of Human Genetics, Salt Lake City, UT, Oct. 25-29, 2005.
223. Kocher K, Morton CC: Cytogenetic approaches to identifying auditory genes. Am. J. Hum. Genet. (Supplement) 2005; 77:156. Presented at the 55th annual meeting of the American Society of Human Genetics, Salt Lake City, UT, Oct. 25-29, 2005.
224. Nance WE, Pandya A, Arnos KS, Lim BG, Morton CC: Estimating age related changes in the causes of deafness by sentinel phenotype analysis. Am. J. Hum. Genet. (Supplement) 2005; 77:43. Presented at the 55th annual meeting of the American Society of Human Genetics, Salt Lake City, UT, Oct. 25-29, 2005.
225. Lu W, Quintero-Rivera F, Fan Y, Ferguson HL, Alkuraya F, Higgins AW, Peters RE, Gronostajski RM, Campbell CG, Rilliet B, Parvex P, Harris DL, Ligon AH, Quade BJ, Bruns GAP, Gusella JF, Morton CC, Maas RL: Disruption of NFIA is associated with neural tube defects and CAKUT. Am. J. Hum. Genet. (Supplement) 2005; 77:178. Presented at the 55th annual meeting of the American Society of Human Genetics, Salt Lake City, UT, Oct. 25-29, 2005.
226. Donovan DJ, Alkuraya FS, Bruns GA, Eisenman R, Gusella JF, Harris DJ, Higgins AW, Kim H-G, Kocher KM, Kulkarni S, Leach NT, Ligon AH, Lu W, Maas RL, Moore SD, Quintero-Rivera F, Saadi I, Williamson RE, Quade BJ, Morton CC: Developmental Genome Anatomy Project (DGAP): Characterization of genes critical to specific developmental pathways Am. J. Hum. Genet. (Supplement) 2005; 77:165. Presented at the 55th annual meeting of the American Society of Human Genetics, Salt Lake City, UT, Oct. 25-29, 2005.
227. Street VA, Kallman JC, Robertson NG, Kuo SF, Morton CC, Phillips JO: A novel DFNA9 mutation in the vWFA2 domain of COCH alters a conserved cysteine residue and intrachain disulfide bond formation resulting in progressive hearing loss and site-specific vestibular and central oculomotor dysfunction. Am. J. Hum. Genet. (Supplement) 2005; 77:208. Presented at the 55th annual meeting of the American Society of Human Genetics, Salt Lake City, UT, Oct. 25-29, 2005.
228. Moore SDP, Offor O, Feryi J, Amrein P, Dal Cin P, Morton CC: Tumor genome anatomy project (TGAP): Gene discovery in tumors in the genome era. Am. J. Hum. Genet. (Supplement) 2005; 77:80. Presented at the 55th annual meeting of the American Society of Human Genetics, Salt Lake City, UT, Oct. 25-29, 2005.
229. Lu W, Quintero-Rivera F, Fan Y, Ferguson HL, Alkuraya F, Higgins AW, Peters RE, Gronostajski RM, Campbell CG, Rilliet B, Parvex P, Harris DJ, Ligon AH, Quade BJ, Bruns GAP, Gusella JF, Morton CC, Maas RL. Disruption of NFIA is associated with neural tube defects and CAKUT. Presented at the annual meeting of the American Society of Nephrology, Philadelphia, PA, Nov. 10-13, 2005.
230. Ferguson H, Kelly C, Bruns G, Gusella J, Harris D, Ligon A, Lu W, Maas R, Quade B, Morton C: Developmental Genome Anatomy Project (DGAP): A resource for patients with balanced chromosomal rearrangements and abnormal phenotypes. Presented at the 24th Annual Education Conference 2005, National Society of Genetic Counselors, Los Angeles, CA, Nov. 12-15, 2005.
231. Giersch ABS, Kasper AO, Morton CC: A mouse organ of Corti cDNA microarray. Presented at the Midwinter Meeting of the Association for Research in Otolaryngology, Baltimore, MD, Feb. 5-9, 2006.
232. Lee C, Stoler JM, Morton CC: What is the final answer? Experience with genome-wide aCGH testing at the Brigham and Women’s and Massachusetts General Hospitals. Presented at the DECIPHER Symposium, The Sanger Center, Hinxton, England, June 18-20, 2006.
233. Alkuraya FS, Saadi I, Lund JL, Turbe-Doan A, Morton C, Maas RL: SUMO1 haploinsufficiency leads to cleft lip and palate. Presented at the 27th annual David W. Smith Workshop on Malformation and Morphogenesis, UCLA Lake Arrowhead Conference Center, Lake Arrowhead, CA, Sept. 8-13, 2006.
234. Robertson NG, Sivakumaran TA, Hamaker SA, Giersch ABS, Morton CC: A Coch knock-in mouse model for late-onset DFNA9 deafness. Am. J. Hum. Genet. (Supplement) 2006; 79:342. Presented at the 56th annual meeting of the American Society of Human Genetics, New Orleans, LA, Oct. 9-13, 2006.
235. Cordero DR, Kim H, Donovan DJ, Morton CC, Quade BJ: The genetics of lateral fusion defects during female reproductive tract development. Am. J. Hum. Genet. (Supplement) 2006; 79:177. Presented at the 56th annual meeting of the American Society of Human Genetics, New Orleans, LA, Oct. 9-13, 2006.
236. Saadi I, Alkuraya FS, Lund JJ, Turbe-Doan A, Morton CC, Maas RL: SUMO1 haploinsufficiency can cause cleft lip and palate. Am. J. Hum. Genet. (Supplement) 2006; 79:20. Presented at the 56th annual meeting of the American Society of Human Genetics, New Orleans, LA, Oct. 9-13, 2006.
237. Williamson R, Alkuraya F, Fan Y, Ferguson H, Gusella J, Harris D, Kelly C, Kocher K, Ligon A, Lu W, Maas R, Quade B, Qunitero-Rivera F, Saadi I, Morton C: The Developmental Genome Anatomy Project (DGAP): Finding genes critical in human development. Am. J. Hum. Genet. (Supplement) 2006; 79:343. Presented at the 56th annual meeting of the American Society of Human Genetics, New Orleans, LA, Oct. 9-13, 2006.
238. Kelly C, Alkuraya F, Fan Y, Ferguson H, Gusella J, Harris D, Kocher K, Ligon A, Lu W, Maas R, Quade B, Quintero-Rivera F, Saadi I, Williamson R, Morton CC: The Developmental Genome Anatomy Project (DGAP): Finding genes critical to human development. Presented at the 25th Annual Education Conference 2006, National Society of Genetic Counselors, Nashville, TN, Nov. 10-14, 2006.
239. Somasundaram P, Huyck KL, Panhuysen CIM, Cuenco KT, Zhang J, Goldhammer H, Jones ES, Lynch AM, Harlow BL, Lee H, Stewart EA, Morton CC: The impact of race as a risk factor for symptom severity and age at diagnosis of uterine leiomyomata among affected sisters. Presented at the Third Annual Junior Investigators' Health Disparities Research Poster Session, Dana Farber/Harvard Cancer Center Cancer Disparities Program-in-Development in partnership with the Harvard Medical School Office of Diversity and Community Partnership, Boston, MA, May 3, 2007.
240. Morton CC, Lee C, Stoler J: The Developmental Genome Anatomy Project: Structural analyses of breakpoints and genomes. Presented at the annual meeting of the DECIPHER, Wellcome Trust Sanger Canter, Hinxton, England, May 16-18, 2007.
241. Jones SM, Mock BE, Robertson N, Morton C: Auditory and vestibular function in a mouse model for DFNA9. Presented at the annual meeting of the American Speech and Language Hearing Association, Boston, MA, Nov. 15-17, 2007.
242. Robertson NG, Jones SM, Sivakumaran TA, Giersch ABS, Hamaker SA, Liberman MC, Maison SF, Miller CE, Morton CC: A targeted Coch missense mutation: a knock-in mouse model for DFNA9 late-onset hearing loss and vestibular dysfunction. Presented at the Molecular Biology of Hearing and Deafness meeting, Wellcome Trust Sanger Center, Hinxton, England, July 11-14, 2007.
243. Brown KK, Williamson R, Arnos K, Reiss J, Crow K, Morton CC: Cytogenetic approaches for identifying novel genes and regulatory elements associated with hearing loss. Presented at the Molecular Biology of Hearing and Deafness meeting, Wellcome Trust Sanger Center, Hinxton, England, July 11-14, 2007.
244. Gabashvili IS, Sokolowski BHA, Morton CC, Giersch ABS: Ion channel gene expression in the inner ear. Presented at the Molecular Biology of Hearing and Deafness meeting, Wellcome Trust Sanger Center, Hinxton, England, July 11-14, 2007.
245. Huyck KL, Panhuysen CIM, T.Cuenco K, Zhang J, Goldhammer H, Jones ES, Somasundaram P, Lynch AM, Harlow BL, Lee H, Stewart EA, Morton CC: The impact of race as a risk factor for symptom severity and age at diagnosis of uterine leiomyomata among affected sisters. Presented at the NICHD Uterine Fibroid Research Update Meeting, Rockville, MD, Sept. 18-19, 2007.
246. Quintero-Rivera F, Higgins AW, Roberts A, Raju Kucherlapati R, Bruns G, Seong IS, Gelb BD, Ferguson H, Maas R, Morton CC, Gusella JF: Disruption of MATR3 and AHDC1 in Noonan-like syndrome. Presented at the 57th annual meeting of the American Society of Human Genetics, San Diego, CA, Oct. 23-27, 2007.
247. Robertson NG, Jones SM, Sivakumaran TA, Giersch ABS, Hamaker SA, Liberman MC, Maison SF, Miller CE, Morton CC: A targeted Coch missense mutation: a knock-in mouse model for DFNA9 late-onset hearing loss and vestibular dysfunction. Presented at the 57th annual meeting of the American Society of Human Genetics, San Diego, CA, Oct. 23-27, 2007.
248. Brown KK, Williamson R, Arnos K, Crow K, Reiss J, Morton CC: Cytogenetic approaches for identifying novel genes and regulatory elements associated with hearing loss. Presented at the 57th annual meeting of the American Society of Human Genetics, San Diego, CA, Oct. 23-27, 2007.
249. Robertson NG, Jones SM, Sivakumaran TA, Giersch ABS, Jurado SA, Call LM, Miller CE, Maison SF, Liberman MC, Morton CC: A targeted Coch missense mutation: a knock-in mouse model for DFNA9 late-onset hearing loss and vestibular dysfunction. Presented at theMidwinter Meeting of the Association for Research in Otolaryngology, Phoenix, AZ, Feb. 16-21, 2008.
MacKenzie JJ, McKenzie K, Brown KK, Morton CC, Harrison KJ: X-linked deafness type 3 (DFN3) phenotype associated with a paracentric inversion. Accepted for presentation at the annual meeting of the European Human Genetics Conference 2008, Barcelona, Spain, May 31-June 3, 2008. |
